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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCC
Full Name:
Netrin receptor DCC
Alias:
colorectal cancer suppressor; deleted in colorectal carcinoma; IGDCC1; immunoglobulin superfamily, DCC subclass, member 1; netrin receptor DCC; tumor suppressor protein DCC
Type:
Receptor, misc.; Immunoglobulin superfamily
Mass (Da):
158457
Number AA:
1447
UniProt ID:
P43146
International Prot ID:
IPI00016422
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006917
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S247
L
Y
F
L
Q
R
P
S
N
V
V
A
I
E
G
Site 2
T479
N
R
E
R
A
L
N
T
T
Q
P
G
S
L
Q
Site 3
T488
Q
P
G
S
L
Q
L
T
V
G
N
L
K
P
E
Site 4
Y809
A
G
E
G
V
P
L
Y
E
S
A
T
T
R
S
Site 5
S811
E
G
V
P
L
Y
E
S
A
T
T
R
S
I
T
Site 6
T813
V
P
L
Y
E
S
A
T
T
R
S
I
T
D
P
Site 7
T814
P
L
Y
E
S
A
T
T
R
S
I
T
D
P
T
Site 8
Y881
K
T
S
E
V
R
L
Y
T
V
R
W
R
T
S
Site 9
S1073
D
T
N
L
I
D
R
S
T
L
N
E
P
P
I
Site 10
T1074
T
N
L
I
D
R
S
T
L
N
E
P
P
I
G
Site 11
S1125
A
V
I
C
T
R
R
S
S
A
Q
Q
R
K
K
Site 12
S1126
V
I
C
T
R
R
S
S
A
Q
Q
R
K
K
R
Site 13
T1135
Q
Q
R
K
K
R
A
T
H
S
A
G
K
R
K
Site 14
S1144
S
A
G
K
R
K
G
S
Q
K
D
L
R
P
P
Site 15
S1178
T
D
P
A
G
R
D
S
P
I
Q
S
C
Q
D
Site 16
S1182
G
R
D
S
P
I
Q
S
C
Q
D
L
T
P
V
Site 17
T1187
I
Q
S
C
Q
D
L
T
P
V
S
H
S
Q
S
Site 18
S1190
C
Q
D
L
T
P
V
S
H
S
Q
S
E
T
Q
Site 19
S1192
D
L
T
P
V
S
H
S
Q
S
E
T
Q
L
G
Site 20
S1194
T
P
V
S
H
S
Q
S
E
T
Q
L
G
S
K
Site 21
T1196
V
S
H
S
Q
S
E
T
Q
L
G
S
K
S
T
Site 22
S1200
Q
S
E
T
Q
L
G
S
K
S
T
S
H
S
G
Site 23
S1202
E
T
Q
L
G
S
K
S
T
S
H
S
G
Q
D
Site 24
S1204
Q
L
G
S
K
S
T
S
H
S
G
Q
D
T
E
Site 25
S1206
G
S
K
S
T
S
H
S
G
Q
D
T
E
E
A
Site 26
T1210
T
S
H
S
G
Q
D
T
E
E
A
G
S
S
M
Site 27
S1215
Q
D
T
E
E
A
G
S
S
M
S
T
L
E
R
Site 28
S1216
D
T
E
E
A
G
S
S
M
S
T
L
E
R
S
Site 29
T1219
E
A
G
S
S
M
S
T
L
E
R
S
L
A
A
Site 30
S1223
S
M
S
T
L
E
R
S
L
A
A
R
R
A
P
Site 31
S1242
M
I
P
M
D
A
Q
S
N
N
P
A
V
V
S
Site 32
Y1261
P
T
L
E
S
A
Q
Y
P
G
I
L
P
S
P
Site 33
S1267
Q
Y
P
G
I
L
P
S
P
T
C
G
Y
P
H
Site 34
T1269
P
G
I
L
P
S
P
T
C
G
Y
P
H
P
Q
Site 35
Y1272
L
P
S
P
T
C
G
Y
P
H
P
Q
F
T
L
Site 36
T1278
G
Y
P
H
P
Q
F
T
L
R
P
V
P
F
P
Site 37
S1298
R
G
F
G
A
G
R
S
Q
S
V
S
E
G
P
Site 38
S1300
F
G
A
G
R
S
Q
S
V
S
E
G
P
T
T
Site 39
S1302
A
G
R
S
Q
S
V
S
E
G
P
T
T
Q
Q
Site 40
T1306
Q
S
V
S
E
G
P
T
T
Q
Q
P
P
M
L
Site 41
T1307
S
V
S
E
G
P
T
T
Q
Q
P
P
M
L
P
Site 42
S1316
Q
P
P
M
L
P
P
S
Q
P
E
H
S
S
S
Site 43
S1321
P
P
S
Q
P
E
H
S
S
S
E
E
A
P
S
Site 44
S1322
P
S
Q
P
E
H
S
S
S
E
E
A
P
S
R
Site 45
S1323
S
Q
P
E
H
S
S
S
E
E
A
P
S
R
T
Site 46
S1328
S
S
S
E
E
A
P
S
R
T
I
P
T
A
C
Site 47
T1333
A
P
S
R
T
I
P
T
A
C
V
R
P
T
H
Site 48
T1339
P
T
A
C
V
R
P
T
H
P
L
R
S
F
A
Site 49
S1344
R
P
T
H
P
L
R
S
F
A
N
P
L
L
P
Site 50
Y1363
A
I
E
P
K
V
P
Y
T
P
L
L
S
Q
P
Site 51
T1364
I
E
P
K
V
P
Y
T
P
L
L
S
Q
P
G
Site 52
S1368
V
P
Y
T
P
L
L
S
Q
P
G
P
T
L
P
Site 53
T1377
P
G
P
T
L
P
K
T
H
V
K
T
A
S
L
Site 54
T1413
S
E
E
S
H
K
P
T
E
D
S
A
N
V
Y
Site 55
S1416
S
H
K
P
T
E
D
S
A
N
V
Y
E
Q
D
Site 56
Y1420
T
E
D
S
A
N
V
Y
E
Q
D
D
L
S
E
Site 57
S1426
V
Y
E
Q
D
D
L
S
E
Q
M
A
S
L
E
Site 58
S1431
D
L
S
E
Q
M
A
S
L
E
G
L
M
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation