PhosphoNET

           
Protein Info 
   
Short Name:  PGI receptor
Full Name:  Prostacyclin receptor
Alias:  Prostaglandin I2 receptor;Prostanoid IP receptor
Type:  G protein-coupled 7TM receptor
Mass (Da):  40956
Number AA:  386
UniProt ID:  P43119
International Prot ID:  IPI00016317
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0004930     PhosphoSite+ KinaseNET
Biological Process:  GO:0007187  GO:0007267   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9ADSCRNLTYVRGSVG
Site 2Y10DSCRNLTYVRGSVGP
Site 3S14NLTYVRGSVGPATST
Site 4Y127ALSHPYLYAQLDGPR
Site 5Y214TLSLCRMYRQQKRHQ
Site 6T230SLGPRPRTGEDEVDH
Site 7S268TQAVAPDSSSEMGDL
Site 8S319LGPAHGDSQTPLSQL
Site 9T321PAHGDSQTPLSQLAS
Site 10S324GDSQTPLSQLASGRR
Site 11S328TPLSQLASGRRDPRA
Site 12S337RRDPRAPSAPVGKEG
Site 13S350EGSCVPLSAWGEGQV
Site 14T363QVEPLPPTQQSSGSA
Site 15S367LPPTQQSSGSAVGTS
Site 16S369PTQQSSGSAVGTSSK
Site 17T373SSGSAVGTSSKAEAS
Site 18S375GSAVGTSSKAEASVA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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