PhosphoNET

           
Protein Info 
   
Short Name:  ECE1
Full Name:  Endothelin-converting enzyme 1
Alias:  ECE; ECE-1; Endothelin converting enzyme 1
Type:  EC 3.4.24.71; Protease; Cell surface; Vesicle protein
Mass (Da):  87164
Number AA:  770
UniProt ID:  P42892
International Prot ID:  IPI00216758
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0033093  GO:0005769 Uniprot OncoNet
Molecular Function:  GO:0004222  GO:0017046  GO:0042803 PhosphoSite+ KinaseNET
Biological Process:  GO:0010815  GO:0010816  GO:0043583 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19LLSALGMSTYKRATL
Site 2Y21SALGMSTYKRATLDE
Site 3T25MSTYKRATLDEEDLV
Site 4S34DEEDLVDSLSEGDAY
Site 5S36EDLVDSLSEGDAYPN
Site 6Y41SLSEGDAYPNGLQVN
Site 7S51GLQVNFHSPRSGQRC
Site 8S759HFRCPPGSPMNPPHK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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