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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Peripherin
Full Name:
Peripherin
Alias:
NEF4; PERI; PRPH; PRPH1
Type:
Cytoskeletal protein
Mass (Da):
53651
Number AA:
470
UniProt ID:
P41219
International Prot ID:
IPI00013164
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
H
H
P
S
G
L
R
A
G
F
S
Site 2
S13
S
G
L
R
A
G
F
S
S
T
S
Y
R
R
T
Site 3
S14
G
L
R
A
G
F
S
S
T
S
Y
R
R
T
F
Site 4
S16
R
A
G
F
S
S
T
S
Y
R
R
T
F
G
P
Site 5
Y17
A
G
F
S
S
T
S
Y
R
R
T
F
G
P
P
Site 6
T20
S
S
T
S
Y
R
R
T
F
G
P
P
P
S
L
Site 7
S26
R
T
F
G
P
P
P
S
L
S
P
G
A
F
S
Site 8
S28
F
G
P
P
P
S
L
S
P
G
A
F
S
Y
S
Site 9
S33
S
L
S
P
G
A
F
S
Y
S
S
S
S
R
F
Site 10
Y34
L
S
P
G
A
F
S
Y
S
S
S
S
R
F
S
Site 11
S35
S
P
G
A
F
S
Y
S
S
S
S
R
F
S
S
Site 12
S36
P
G
A
F
S
Y
S
S
S
S
R
F
S
S
S
Site 13
S37
G
A
F
S
Y
S
S
S
S
R
F
S
S
S
R
Site 14
S38
A
F
S
Y
S
S
S
S
R
F
S
S
S
R
L
Site 15
S41
Y
S
S
S
S
R
F
S
S
S
R
L
L
G
S
Site 16
S42
S
S
S
S
R
F
S
S
S
R
L
L
G
S
A
Site 17
S43
S
S
S
R
F
S
S
S
R
L
L
G
S
A
S
Site 18
S48
S
S
S
R
L
L
G
S
A
S
P
S
S
S
V
Site 19
S50
S
R
L
L
G
S
A
S
P
S
S
S
V
R
L
Site 20
S53
L
G
S
A
S
P
S
S
S
V
R
L
G
S
F
Site 21
S54
G
S
A
S
P
S
S
S
V
R
L
G
S
F
R
Site 22
S59
S
S
S
V
R
L
G
S
F
R
S
P
R
A
G
Site 23
S62
V
R
L
G
S
F
R
S
P
R
A
G
A
G
A
Site 24
S75
G
A
L
L
R
L
P
S
E
R
L
D
F
S
M
Site 25
S81
P
S
E
R
L
D
F
S
M
A
E
A
L
N
Q
Site 26
T93
L
N
Q
E
F
L
A
T
R
S
N
E
K
Q
E
Site 27
S130
A
A
L
R
G
E
L
S
Q
A
R
G
Q
E
P
Site 28
T208
R
K
D
V
D
D
A
T
L
S
R
L
E
L
E
Site 29
S210
D
V
D
D
A
T
L
S
R
L
E
L
E
R
K
Site 30
S242
E
L
R
D
L
Q
V
S
V
E
S
Q
Q
V
Q
Site 31
T256
Q
Q
V
E
V
E
A
T
V
K
P
E
L
T
A
Site 32
Y272
L
R
D
I
R
A
Q
Y
E
S
I
A
A
K
N
Site 33
S274
D
I
R
A
Q
Y
E
S
I
A
A
K
N
L
Q
Site 34
Y287
L
Q
E
A
E
E
W
Y
K
S
K
Y
A
D
L
Site 35
S289
E
A
E
E
W
Y
K
S
K
Y
A
D
L
S
D
Site 36
Y291
E
E
W
Y
K
S
K
Y
A
D
L
S
D
A
A
Site 37
S295
K
S
K
Y
A
D
L
S
D
A
A
N
R
N
H
Site 38
S315
A
K
Q
E
M
N
E
S
R
R
Q
I
Q
S
L
Site 39
S321
E
S
R
R
Q
I
Q
S
L
T
C
E
V
D
G
Site 40
T323
R
R
Q
I
Q
S
L
T
C
E
V
D
G
L
R
Site 41
T332
E
V
D
G
L
R
G
T
N
E
A
L
L
R
Q
Site 42
Y379
M
A
R
H
L
R
E
Y
Q
E
L
L
N
V
K
Site 43
Y396
L
D
I
E
I
A
T
Y
R
K
L
L
E
G
E
Site 44
S405
K
L
L
E
G
E
E
S
R
I
S
V
P
V
H
Site 45
S408
E
G
E
E
S
R
I
S
V
P
V
H
S
F
A
Site 46
T422
A
S
L
N
I
K
T
T
V
P
E
V
E
P
P
Site 47
S432
E
V
E
P
P
Q
D
S
H
S
R
K
T
V
L
Site 48
S434
E
P
P
Q
D
S
H
S
R
K
T
V
L
I
K
Site 49
T437
Q
D
S
H
S
R
K
T
V
L
I
K
T
I
E
Site 50
T442
R
K
T
V
L
I
K
T
I
E
T
R
N
G
E
Site 51
S454
N
G
E
V
V
T
E
S
Q
K
E
Q
R
S
E
Site 52
S460
E
S
Q
K
E
Q
R
S
E
L
D
K
S
S
A
Site 53
S465
Q
R
S
E
L
D
K
S
S
A
H
S
Y
_
_
Site 54
S466
R
S
E
L
D
K
S
S
A
H
S
Y
_
_
_
Site 55
Y470
D
K
S
S
A
H
S
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation