PhosphoNET

           
Protein Info 
   
Short Name:  AQP2
Full Name:  Aquaporin-2
Alias:  ADH water channel; AQP-CD; Aquaporin 2; Aquaporin 2 (collecting duct); Aquaporin-CD; Collecting duct water channel protein; Water channel protein for renal collecting duct; WCH-CD
Type:  Channel protein
Mass (Da):  28837
Number AA:  271
UniProt ID:  P41181
International Prot ID:  IPI00012818
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016324  GO:0031410  GO:0016021 Uniprot OncoNet
Molecular Function:  GO:0015250     PhosphoSite+ KinaseNET
Biological Process:  GO:0007588  GO:0055085   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S122DLAVNALSNSTTAGQ
Site 2T159RRGENPGTPALSIGF
Site 3Y178GHLLGIHYTGCSMNP
Site 4S229VLFPPAKSLSERLAV
Site 5S231FPPAKSLSERLAVLK
Site 6T244LKGLEPDTDWEEREV
Site 7S256REVRRRQSVELHSPQ
Site 8S261RQSVELHSPQSLPRG
Site 9S264VELHSPQSLPRGTKA
Site 10T269PQSLPRGTKA_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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