PhosphoNET

           
Protein Info 
   
Short Name:  Cip1 (p21)
Full Name:  Cyclin-dependent kinase inhibitor 1
Alias:  CAP20; CDKN1; CDKN1A; CDN1A; CIP1; MDA6; Melanoma differentiation associated protein; PIC1; SDI1; WAF1
Type:  Inhibitor protein
Mass (Da):  17988
Number AA:  164
UniProt ID:  P38936
International Prot ID:  IPI00009384
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000307  GO:0005829  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0004861  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0006977  GO:0000082  GO:0000086 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S27RLFGPVDSEQLSRDC
Site 2S31PVDSEQLSRDCDALM
Site 3T55RWNFDFVTETPLEGD
Site 4T57NFDFVTETPLEGDFA
Site 5Y77GLGLPKLYLPTGPRR
Site 6T97GGGRRPGTSPALLQG
Site 7S98GGRRPGTSPALLQGT
Site 8S114EEDHVDLSLSCTLVP
Site 9S116DHVDLSLSCTLVPRS
Site 10S123SCTLVPRSGEQAEGS
Site 11S130SGEQAEGSPGGPGDS
Site 12S137SPGGPGDSQGRKRRQ
Site 13T145QGRKRRQTSMTDFYH
Site 14S146GRKRRQTSMTDFYHS
Site 15T148KRRQTSMTDFYHSKR
Site 16Y151QTSMTDFYHSKRRLI
Site 17S153SMTDFYHSKRRLIFS
Site 18S160SKRRLIFSKRKP___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation