PhosphoNET

           
Protein Info 
   
Short Name:  SREBF1
Full Name:  Sterol regulatory element-binding protein 1
Alias:  BHLHd1; SRBP1; SREBP1; SREBP-1c; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
Type:  Transcription protein
Mass (Da):  121675
Number AA:  1147
UniProt ID:  P36956
International Prot ID:  IPI00418428
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0031410  GO:0005783 Uniprot OncoNet
Molecular Function:  GO:0003702  GO:0005515  GO:0032810 PhosphoSite+ KinaseNET
Biological Process:  GO:0009267  GO:0008203  GO:0045944 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MDEPPFSEAALEQA
Site 2S41QLINNQDSDFPGLFD
Site 3Y51PGLFDPPYAGSGAGG
Site 4S54FDPPYAGSGAGGTDP
Site 5T59AGSGAGGTDPASPDT
Site 6S63AGGTDPASPDTSSPG
Site 7T66TDPASPDTSSPGSLS
Site 8S67DPASPDTSSPGSLSP
Site 9S68PASPDTSSPGSLSPP
Site 10S71PDTSSPGSLSPPPAT
Site 11S73TSSPGSLSPPPATLS
Site 12T78SLSPPPATLSSSLEA
Site 13S88SSLEAFLSGPQAAPS
Site 14S95SGPQAAPSPLSPPQP
Site 15S98QAAPSPLSPPQPAPT
Site 16T105SPPQPAPTPLKMYPS
Site 17Y110APTPLKMYPSMPAFS
Site 18S112TPLKMYPSMPAFSPG
Site 19S117YPSMPAFSPGPGIKE
Site 20S126GPGIKEESVPLSILQ
Site 21S130KEESVPLSILQTPTP
Site 22S158APAPPQFSSTPVLGY
Site 23S159PAPPQFSSTPVLGYP
Site 24T160APPQFSSTPVLGYPS
Site 25Y165SSTPVLGYPSPPGGF
Site 26S167TPVLGYPSPPGGFST
Site 27S173PSPPGGFSTGSPPGN
Site 28T174SPPGGFSTGSPPGNT
Site 29S176PGGFSTGSPPGNTQQ
Site 30T181TGSPPGNTQQPLPGL
Site 31S200PPGVPPVSLHTQVQS
Site 32T253KADSLLLTAMKTDGA
Site 33S312INRLAAGSKAPASAQ
Site 34S317AGSKAPASAQSRGEK
Site 35S337AIEKRYRSSINDKII
Site 36S338IEKRYRSSINDKIIE
Site 37S360TEAKLNKSAVLRKAI
Site 38Y369VLRKAIDYIRFLQHS
Site 39S376YIRFLQHSNQKLKQE
Site 40S386KLKQENLSLRTAVHK
Site 41S394LRTAVHKSKSLKDLV
Site 42S396TAVHKSKSLKDLVSA
Site 43S402KSLKDLVSACGSGGN
Site 44T424VKTEVEDTLTPPPSD
Site 45T426TEVEDTLTPPPSDAG
Site 46S430DTLTPPPSDAGSPFQ
Site 47S434PPPSDAGSPFQSSPL
Site 48S438DAGSPFQSSPLSLGS
Site 49S439AGSPFQSSPLSLGSR
Site 50S442PFQSSPLSLGSRGSG
Site 51S445SSPLSLGSRGSGSGG
Site 52S448LSLGSRGSGSGGSGS
Site 53S450LGSRGSGSGGSGSDS
Site 54S453RGSGSGGSGSDSEPD
Site 55S455SGSGGSGSDSEPDSP
Site 56S457SGGSGSDSEPDSPVF
Site 57S461GSDSEPDSPVFEDSK
Site 58S467DSPVFEDSKAKPEQR
Site 59S476AKPEQRPSLHSRGML
Site 60S479EQRPSLHSRGMLDRS
Site 61S486SRGMLDRSRLALCTL
Site 62S514LGARGLPSPSDTTSV
Site 63S516ARGLPSPSDTTSVYH
Site 64T518GLPSPSDTTSVYHSP
Site 65S520PSPSDTTSVYHSPGR
Site 66Y522PSDTTSVYHSPGRNV
Site 67S524DTTSVYHSPGRNVLG
Site 68T532PGRNVLGTESRDGPG
Site 69T572FVYGEPVTRPHSGPA
Site 70S576EPVTRPHSGPAVYFW
Site 71Y581PHSGPAVYFWRHRKQ
Site 72T681HKLHQLHTMGKHTGG
Site 73S753RQACLAQSGSVPPAM
Site 74S781DGDWSVLSTPWESLY
Site 75T782GDWSVLSTPWESLYS
Site 76Y788STPWESLYSLAGNPV
Site 77S789TPWESLYSLAGNPVD
Site 78S823CVTQPNPSPGSADGD
Site 79S826QPNPSPGSADGDKEF
Site 80S834ADGDKEFSDALGYLQ
Site 81Y855DAAGAPAYSFSISSS
Site 82S860PAYSFSISSSMATTT
Site 83S911LPRVLQESERPLPRA
Site 84S941KAESGPASLTICEKA
Site 85T943ESGPASLTICEKASG
Site 86Y951ICEKASGYLQDSLAT
Site 87S955ASGYLQDSLATTPAS
Site 88T959LQDSLATTPASSSID
Site 89S983LLLVVRTSLWRQQQP
Site 90S1001APAAQGTSSRPQASA
Site 91S1002PAAQGTSSRPQASAL
Site 92S1019RGFQRDLSSLRRLAQ
Site 93S1020GFQRDLSSLRRLAQS
Site 94S1027SLRRLAQSFRPAMRR
Site 95S1049ARLMAGASPTRTHQL
Site 96T1053AGASPTRTHQLLDRS
Site 97S1060THQLLDRSLRRRAGP
Site 98T1082AELEPRPTRREHAEA
Site 99S1103YLPPGFLSAPGQRVG
Site 100T1118MLAEAARTLEKLGDR
Site 101T1143MRLGGGTTVTSS___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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