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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DEK
Full Name:
Protein DEK
Alias:
D6S231E; DEK oncogene; DEK oncogene (DNA binding)
Type:
DNA binding protein; Transcription factor
Mass (Da):
42674
Number AA:
375
UniProt ID:
P35659
International Prot ID:
IPI00020021
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0042393
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
GO:0007165
GO:0019079
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
P
A
A
E
G
E
G
T
P
T
Q
P
A
S
E
Site 2
T15
A
E
G
E
G
T
P
T
Q
P
A
S
E
K
E
Site 3
S19
G
T
P
T
Q
P
A
S
E
K
E
P
E
M
P
Site 4
S32
M
P
G
P
R
E
E
S
E
E
E
E
D
E
D
Site 5
S51
E
E
E
E
K
E
K
S
L
I
V
E
G
K
R
Site 6
T67
K
K
K
V
E
R
L
T
M
Q
V
S
S
L
Q
Site 7
S71
E
R
L
T
M
Q
V
S
S
L
Q
R
E
P
F
Site 8
S72
R
L
T
M
Q
V
S
S
L
Q
R
E
P
F
T
Site 9
T79
S
L
Q
R
E
P
F
T
I
A
Q
G
K
G
Q
Site 10
S99
E
R
I
H
F
F
L
S
K
K
K
T
D
E
L
Site 11
T103
F
F
L
S
K
K
K
T
D
E
L
R
N
L
H
Site 12
Y114
R
N
L
H
K
L
L
Y
N
R
P
G
T
V
S
Site 13
T119
L
L
Y
N
R
P
G
T
V
S
S
L
K
K
N
Site 14
S121
Y
N
R
P
G
T
V
S
S
L
K
K
N
V
G
Site 15
S122
N
R
P
G
T
V
S
S
L
K
K
N
V
G
Q
Site 16
S159
F
R
N
A
M
L
K
S
I
C
E
V
L
D
L
Site 17
S169
E
V
L
D
L
E
R
S
G
V
N
S
E
L
V
Site 18
S173
L
E
R
S
G
V
N
S
E
L
V
K
R
I
L
Site 19
S189
F
L
M
H
P
K
P
S
G
K
P
L
P
K
S
Site 20
S196
S
G
K
P
L
P
K
S
K
K
T
C
S
K
G
Site 21
T199
P
L
P
K
S
K
K
T
C
S
K
G
S
K
K
Site 22
S201
P
K
S
K
K
T
C
S
K
G
S
K
K
E
R
Site 23
S204
K
K
T
C
S
K
G
S
K
K
E
R
N
S
S
Site 24
S210
G
S
K
K
E
R
N
S
S
G
M
A
R
K
A
Site 25
S211
S
K
K
E
R
N
S
S
G
M
A
R
K
A
K
Site 26
T220
M
A
R
K
A
K
R
T
K
C
P
E
I
L
S
Site 27
S227
T
K
C
P
E
I
L
S
D
E
S
S
S
D
E
Site 28
S230
P
E
I
L
S
D
E
S
S
S
D
E
D
E
K
Site 29
S231
E
I
L
S
D
E
S
S
S
D
E
D
E
K
K
Site 30
S232
I
L
S
D
E
S
S
S
D
E
D
E
K
K
N
Site 31
S243
E
K
K
N
K
E
E
S
S
D
D
E
D
K
E
Site 32
S244
K
K
N
K
E
E
S
S
D
D
E
D
K
E
S
Site 33
S251
S
D
D
E
D
K
E
S
E
E
E
P
P
K
K
Site 34
S271
K
P
K
Q
K
A
T
S
K
S
K
K
S
V
K
Site 35
S273
K
Q
K
A
T
S
K
S
K
K
S
V
K
S
A
Site 36
S276
A
T
S
K
S
K
K
S
V
K
S
A
N
V
K
Site 37
S279
K
S
K
K
S
V
K
S
A
N
V
K
K
A
D
Site 38
S287
A
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
Site 39
S288
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
Site 40
T289
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
S
Site 41
T290
K
K
A
D
S
S
T
T
K
K
N
Q
N
S
S
Site 42
S296
T
T
K
K
N
Q
N
S
S
K
K
E
S
E
S
Site 43
S297
T
K
K
N
Q
N
S
S
K
K
E
S
E
S
E
Site 44
S301
Q
N
S
S
K
K
E
S
E
S
E
D
S
S
D
Site 45
S303
S
S
K
K
E
S
E
S
E
D
S
S
D
D
E
Site 46
S306
K
E
S
E
S
E
D
S
S
D
D
E
P
L
I
Site 47
S307
E
S
E
S
E
D
S
S
D
D
E
P
L
I
K
Site 48
T321
K
K
L
K
K
P
P
T
D
E
E
L
K
E
T
Site 49
T328
T
D
E
E
L
K
E
T
I
K
K
L
L
A
S
Site 50
S335
T
I
K
K
L
L
A
S
A
N
L
E
E
V
T
Site 51
Y351
K
Q
I
C
K
K
V
Y
E
N
Y
P
T
Y
D
Site 52
Y354
C
K
K
V
Y
E
N
Y
P
T
Y
D
L
T
E
Site 53
T356
K
V
Y
E
N
Y
P
T
Y
D
L
T
E
R
K
Site 54
Y357
V
Y
E
N
Y
P
T
Y
D
L
T
E
R
K
D
Site 55
T360
N
Y
P
T
Y
D
L
T
E
R
K
D
F
I
K
Site 56
T368
E
R
K
D
F
I
K
T
T
V
K
E
L
I
S
Site 57
T369
R
K
D
F
I
K
T
T
V
K
E
L
I
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation