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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTNNB1
Full Name:
Catenin beta-1
Alias:
Beta-catenin; Catenin, beta; CATNB; CTNB1; CTNNB
Type:
Cytoskeletal protein
Mass (Da):
85497
Number AA:
781
UniProt ID:
P35222
International Prot ID:
IPI00017292
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034747
GO:0030877
GO:0070369
Uniprot
OncoNet
Molecular Function:
GO:0070411
GO:0050681
GO:0045296
PhosphoSite+
KinaseNET
Biological Process:
GO:0060070
GO:0030521
GO:0016337
Phosida
TranscriptoNet
STRING
Kinexus Products
Catenin beta-1 (G38-P44, human) peptide - Powder PE-01BFL90L#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BFL90L#Catenin beta-1 (G38-P44, human) peptide - Powder PE-01BFM99H#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BFM99H
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
P
D
R
K
A
A
V
S
H
W
Q
Q
Q
S
Y
Site 2
S29
V
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
Site 3
Y30
S
H
W
Q
Q
Q
S
Y
L
D
S
G
I
H
S
Site 4
S33
Q
Q
Q
S
Y
L
D
S
G
I
H
S
G
A
T
Site 5
S37
Y
L
D
S
G
I
H
S
G
A
T
T
T
A
P
Site 6
T41
G
I
H
S
G
A
T
T
T
A
P
S
L
S
G
Site 7
S45
G
A
T
T
T
A
P
S
L
S
G
K
G
N
P
Site 8
S47
T
T
T
A
P
S
L
S
G
K
G
N
P
E
E
Site 9
T59
P
E
E
E
D
V
D
T
S
Q
V
L
Y
E
W
Site 10
S60
E
E
E
D
V
D
T
S
Q
V
L
Y
E
W
E
Site 11
Y64
V
D
T
S
Q
V
L
Y
E
W
E
Q
G
F
S
Site 12
S73
W
E
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
Site 13
T75
Q
G
F
S
Q
S
F
T
Q
E
Q
V
A
D
I
Site 14
Y86
V
A
D
I
D
G
Q
Y
A
M
T
R
A
Q
R
Site 15
T102
R
A
A
M
F
P
E
T
L
D
E
G
M
Q
I
Site 16
T112
E
G
M
Q
I
P
S
T
Q
F
D
A
A
H
P
Site 17
T120
Q
F
D
A
A
H
P
T
N
V
Q
R
L
A
E
Site 18
S129
V
Q
R
L
A
E
P
S
Q
M
L
K
H
A
V
Site 19
Y142
A
V
V
N
L
I
N
Y
Q
D
D
A
E
L
A
Site 20
S179
A
V
M
V
H
Q
L
S
K
K
E
A
S
R
H
Site 21
S191
S
R
H
A
I
M
R
S
P
Q
M
V
S
A
I
Site 22
S196
M
R
S
P
Q
M
V
S
A
I
V
R
T
M
Q
Site 23
T205
I
V
R
T
M
Q
N
T
N
D
V
E
T
A
R
Site 24
T210
Q
N
T
N
D
V
E
T
A
R
C
T
A
G
T
Site 25
T214
D
V
E
T
A
R
C
T
A
G
T
L
H
N
L
Site 26
T217
T
A
R
C
T
A
G
T
L
H
N
L
S
H
H
Site 27
S222
A
G
T
L
H
N
L
S
H
H
R
E
G
L
L
Site 28
S246
A
L
V
K
M
L
G
S
P
V
D
S
V
L
F
Site 29
Y306
D
C
L
Q
I
L
A
Y
G
N
Q
E
S
K
L
Site 30
Y331
L
V
N
I
M
R
T
Y
T
Y
E
K
L
L
W
Site 31
T332
V
N
I
M
R
T
Y
T
Y
E
K
L
L
W
T
Site 32
Y333
N
I
M
R
T
Y
T
Y
E
K
L
L
W
T
T
Site 33
T339
T
Y
E
K
L
L
W
T
T
S
R
V
L
K
V
Site 34
S348
S
R
V
L
K
V
L
S
V
C
S
S
N
K
P
Site 35
T371
Q
A
L
G
L
H
L
T
D
P
S
Q
R
L
V
Site 36
S374
G
L
H
L
T
D
P
S
Q
R
L
V
Q
N
C
Site 37
S389
L
W
T
L
R
N
L
S
D
A
A
T
K
Q
E
Site 38
T393
R
N
L
S
D
A
A
T
K
Q
E
G
M
E
G
Site 39
T461
A
G
D
R
E
D
I
T
E
P
A
I
C
A
L
Site 40
T472
I
C
A
L
R
H
L
T
S
R
H
Q
E
A
E
Site 41
S473
C
A
L
R
H
L
T
S
R
H
Q
E
A
E
M
Site 42
Y489
Q
N
A
V
R
L
H
Y
G
L
P
V
V
V
K
Site 43
S502
V
K
L
L
H
P
P
S
H
W
P
L
I
K
A
Site 44
T547
L
V
R
A
H
Q
D
T
Q
R
R
T
S
M
G
Site 45
T551
H
Q
D
T
Q
R
R
T
S
M
G
G
T
Q
Q
Site 46
S552
Q
D
T
Q
R
R
T
S
M
G
G
T
Q
Q
Q
Site 47
T556
R
R
T
S
M
G
G
T
Q
Q
Q
F
V
E
G
Site 48
T574
E
E
I
V
E
G
C
T
G
A
L
H
I
L
A
Site 49
S605
L
F
V
Q
L
L
Y
S
P
I
E
N
I
Q
R
Site 50
T641
E
G
A
T
A
P
L
T
E
L
L
H
S
R
N
Site 51
T653
S
R
N
E
G
V
A
T
Y
A
A
A
V
L
F
Site 52
Y654
R
N
E
G
V
A
T
Y
A
A
A
V
L
F
R
Site 53
S663
A
A
V
L
F
R
M
S
E
D
K
P
Q
D
Y
Site 54
Y670
S
E
D
K
P
Q
D
Y
K
K
R
L
S
V
E
Site 55
S675
Q
D
Y
K
K
R
L
S
V
E
L
T
S
S
L
Site 56
T679
K
R
L
S
V
E
L
T
S
S
L
F
R
T
E
Site 57
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Site 58
Y709
A
Q
G
E
P
L
G
Y
R
Q
D
D
P
S
Y
Site 59
S715
G
Y
R
Q
D
D
P
S
Y
R
S
F
H
S
G
Site 60
Y716
Y
R
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Site 61
S718
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Site 62
S721
P
S
Y
R
S
F
H
S
G
G
Y
G
Q
D
A
Site 63
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Site 64
S771
D
G
L
P
P
G
D
S
N
Q
L
A
W
F
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation