PhosphoNET

           
Protein Info 
   
Short Name:  DUT
Full Name:  Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Alias:  dUTP pyrophosphatase
Type:  Mitochondrial; EC 3.6.1.23; Hydrolase; Nucleotide Metabolism - pyrimidine; DNA replication
Mass (Da):  26706
Number AA:  252
UniProt ID:  P33316
International Prot ID:  IPI00375015
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005739  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0004170  GO:0000287  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006260  GO:0046080  GO:0006220 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S21FLTSLLRSAMQNARG
Site 2T29AMQNARGTAEGRSRG
Site 3T37AEGRSRGTLRARPAP
Site 4S58HGIPRPLSSAGRLSQ
Site 5S59GIPRPLSSAGRLSQG
Site 6S64LSSAGRLSQGCRGAS
Site 7S71SQGCRGASTVGAAGW
Site 8T72QGCRGASTVGAAGWK
Site 9S88ELPKAGGSPAPGPET
Site 10T95SPAPGPETPAISPSK
Site 11S99GPETPAISPSKRARP
Site 12S101ETPAISPSKRARPAE
Site 13S120QLRFARLSEHATAPT
Site 14T124ARLSEHATAPTRGSA
Site 15S130ATAPTRGSARAAGYD
Site 16Y136GSARAAGYDLYSAYD
Site 17Y139RAAGYDLYSAYDYTI
Site 18S140AAGYDLYSAYDYTIP
Site 19Y142GYDLYSAYDYTIPPM
Site 20Y144DLYSAYDYTIPPMEK
Site 21T145LYSAYDYTIPPMEKA
Site 22Y167IALPSGCYGRVAPRS
Site 23S174YGRVAPRSGLAAKHF
Site 24T239EVQALDDTERGSGGF
Site 25S243LDDTERGSGGFGSTG
Site 26S248RGSGGFGSTGKN___
Site 27T249GSGGFGSTGKN____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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