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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRPAP1
Full Name:
Alpha-2-macroglobulin receptor-associated protein
Alias:
A2MRAP; Alpha-2-macroglobulin receptor-associated; Alpha-2-MRAP; AMRP;Low density lipoprotein receptor-related protein-associated 1; Low density lipoprotein receptor-related protein-associated protein 1
Type:
Receptor, miscellaneous
Mass (Da):
41466
Number AA:
357
UniProt ID:
P30533
International Prot ID:
IPI00026848
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005783
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0001871
GO:0004871
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0006810
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
P
R
R
V
R
S
F
L
R
G
L
P
A
Site 2
S30
L
G
P
W
P
A
A
S
H
G
G
K
Y
S
R
Site 3
Y35
A
A
S
H
G
G
K
Y
S
R
E
K
N
Q
P
Site 4
S36
A
S
H
G
G
K
Y
S
R
E
K
N
Q
P
K
Site 5
S45
E
K
N
Q
P
K
P
S
P
K
R
E
S
G
E
Site 6
S50
K
P
S
P
K
R
E
S
G
E
E
F
R
M
E
Site 7
Y122
L
N
V
I
L
A
K
Y
G
L
D
G
K
K
D
Site 8
T134
K
K
D
A
R
Q
V
T
S
N
S
L
S
G
T
Site 9
S135
K
D
A
R
Q
V
T
S
N
S
L
S
G
T
Q
Site 10
S137
A
R
Q
V
T
S
N
S
L
S
G
T
Q
E
D
Site 11
S139
Q
V
T
S
N
S
L
S
G
T
Q
E
D
G
L
Site 12
T141
T
S
N
S
L
S
G
T
Q
E
D
G
L
D
D
Site 13
T160
K
L
W
H
K
A
K
T
S
G
K
F
S
G
E
Site 14
S161
L
W
H
K
A
K
T
S
G
K
F
S
G
E
E
Site 15
S165
A
K
T
S
G
K
F
S
G
E
E
L
D
K
L
Site 16
T192
E
Y
N
V
L
L
E
T
L
S
R
T
E
E
I
Site 17
S194
N
V
L
L
E
T
L
S
R
T
E
E
I
H
E
Site 18
S205
E
I
H
E
N
V
I
S
P
S
D
L
S
D
I
Site 19
S207
H
E
N
V
I
S
P
S
D
L
S
D
I
K
G
Site 20
S215
D
L
S
D
I
K
G
S
V
L
H
S
R
H
T
Site 21
S219
I
K
G
S
V
L
H
S
R
H
T
E
L
K
E
Site 22
T222
S
V
L
H
S
R
H
T
E
L
K
E
K
L
R
Site 23
S230
E
L
K
E
K
L
R
S
I
N
Q
G
L
D
R
Site 24
S242
L
D
R
L
R
R
V
S
H
Q
G
Y
S
T
E
Site 25
Y246
R
R
V
S
H
Q
G
Y
S
T
E
A
E
F
E
Site 26
S247
R
V
S
H
Q
G
Y
S
T
E
A
E
F
E
E
Site 27
T248
V
S
H
Q
G
Y
S
T
E
A
E
F
E
E
P
Site 28
T270
L
A
Q
S
A
N
L
T
D
K
E
L
E
A
F
Site 29
Y294
K
I
E
K
H
N
H
Y
Q
K
Q
L
E
I
A
Site 30
S310
E
K
L
R
H
A
E
S
V
G
D
G
E
R
V
Site 31
S318
V
G
D
G
E
R
V
S
R
S
R
E
K
H
A
Site 32
S320
D
G
E
R
V
S
R
S
R
E
K
H
A
L
L
Site 33
Y336
G
R
T
K
E
L
G
Y
T
V
K
K
H
L
Q
Site 34
T337
R
T
K
E
L
G
Y
T
V
K
K
H
L
Q
D
Site 35
S346
K
K
H
L
Q
D
L
S
G
R
I
S
R
A
R
Site 36
S350
Q
D
L
S
G
R
I
S
R
A
R
H
N
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation