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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cyclin D3
Full Name:
G1/S-specific cyclin-D3
Alias:
CCND3; CGD3; Cyl-3
Type:
Protein-serine kinase regulatory subunit, activator, cyclin
Mass (Da):
32520
Number AA:
292
UniProt ID:
P30281
International Prot ID:
IPI00025817
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000307
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0045737
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
G
D
Q
R
V
L
Q
S
L
L
R
L
E
E
R
Site 2
Y38
L
L
R
L
E
E
R
Y
V
P
R
A
S
Y
F
Site 3
Y44
R
Y
V
P
R
A
S
Y
F
Q
C
V
Q
R
E
Site 4
Y88
A
M
N
Y
L
D
R
Y
L
S
C
V
P
T
R
Site 5
S90
N
Y
L
D
R
Y
L
S
C
V
P
T
R
K
A
Site 6
T94
R
Y
L
S
C
V
P
T
R
K
A
Q
L
Q
L
Site 7
T116
L
A
S
K
L
R
E
T
T
P
L
T
I
E
K
Site 8
T117
A
S
K
L
R
E
T
T
P
L
T
I
E
K
L
Site 9
S133
I
Y
T
D
H
A
V
S
P
R
Q
L
R
D
W
Site 10
S169
A
F
I
L
H
R
L
S
L
P
R
D
R
Q
A
Site 11
S254
I
E
A
A
L
R
E
S
L
R
E
A
S
Q
T
Site 12
S259
R
E
S
L
R
E
A
S
Q
T
S
S
S
P
A
Site 13
T261
S
L
R
E
A
S
Q
T
S
S
S
P
A
P
K
Site 14
S263
R
E
A
S
Q
T
S
S
S
P
A
P
K
A
P
Site 15
S264
E
A
S
Q
T
S
S
S
P
A
P
K
A
P
R
Site 16
S273
A
P
K
A
P
R
G
S
S
S
Q
G
P
S
Q
Site 17
S274
P
K
A
P
R
G
S
S
S
Q
G
P
S
Q
T
Site 18
S275
K
A
P
R
G
S
S
S
Q
G
P
S
Q
T
S
Site 19
S279
G
S
S
S
Q
G
P
S
Q
T
S
T
P
T
D
Site 20
T281
S
S
Q
G
P
S
Q
T
S
T
P
T
D
V
T
Site 21
S282
S
Q
G
P
S
Q
T
S
T
P
T
D
V
T
A
Site 22
T283
Q
G
P
S
Q
T
S
T
P
T
D
V
T
A
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation