PhosphoNET

           
Protein Info 
   
Short Name:  GHF1
Full Name:  Pituitary-specific positive transcription factor 1
Alias:  Growth hormone factor 1
Type:  Transcription protein
Mass (Da):  32912
Number AA:  291
UniProt ID:  P28069
International Prot ID:  IPI00216420
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0008285  GO:0043193  GO:0006366 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11QAFTSADTFIPLNSD
Site 2S17DTFIPLNSDASATLP
Site 3Y53STATGLHYSVPSCHY
Site 4S54TATGLHYSVPSCHYG
Site 5T66HYGNQPSTYGVMAGS
Site 6Y67YGNQPSTYGVMAGSL
Site 7Y79GSLTPCLYKFPDHTL
Site 8T85LYKFPDHTLSHGFPP
Site 9S87KFPDHTLSHGFPPIH
Site 10T103PLLAEDPTAADFKQE
Site 11S115KQELRRKSKLVEEPI
Site 12S126EEPIDMDSPEIRELE
Site 13Y148VRRIKLGYTQTNVGE
Site 14S166AVHGSEFSQTTICRF
Site 15T168HGSEFSQTTICRFEN
Site 16T169GSEFSQTTICRFENL
Site 17S179RFENLQLSFKNACKL
Site 18S191CKLKAILSKWLEEAE
Site 19Y204AEQVGALYNEKVGAN
Site 20T219ERKRKRRTTISIAAK
Site 21T220RKRKRRTTISIAAKD
Site 22S222RKRRTTISIAAKDAL
Site 23S241GEQNKPSSQEIMRMA
Site 24T274QREKRVKTSLNQSLF
Site 25S275REKRVKTSLNQSLFS
Site 26S279VKTSLNQSLFSISKE
Site 27S282SLNQSLFSISKEHLE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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