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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CANX
Full Name:
Calnexin
Alias:
IP90; Major histocompatibility complex class I antigen-binding protein p88; P90
Type:
Calcium binding protein
Mass (Da):
67568
Number AA:
592
UniProt ID:
P27824
International Prot ID:
IPI00020984
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005783
GO:0005789
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0001525
GO:0006457
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Calnexin pan-specific antibody AB-NN136-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN136-2#Calnexin pan-specific antibody AB-NN136-4#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN136-4#Calnexin pan-specific antibody AB-NN136-5#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN136-5
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
V
I
E
E
V
E
D
S
K
P
D
T
T
A
P
Site 2
T49
V
E
D
S
K
P
D
T
T
A
P
P
S
S
P
Site 3
T50
E
D
S
K
P
D
T
T
A
P
P
S
S
P
K
Site 4
S54
P
D
T
T
A
P
P
S
S
P
K
V
T
Y
K
Site 5
S55
D
T
T
A
P
P
S
S
P
K
V
T
Y
K
A
Site 6
T59
P
P
S
S
P
K
V
T
Y
K
A
P
V
P
T
Site 7
Y60
P
S
S
P
K
V
T
Y
K
A
P
V
P
T
G
Site 8
Y70
P
V
P
T
G
E
V
Y
F
A
D
S
F
D
R
Site 9
S74
G
E
V
Y
F
A
D
S
F
D
R
G
T
L
S
Site 10
T79
A
D
S
F
D
R
G
T
L
S
G
W
I
L
S
Site 11
S81
S
F
D
R
G
T
L
S
G
W
I
L
S
K
A
Site 12
S86
T
L
S
G
W
I
L
S
K
A
K
K
D
D
T
Site 13
T93
S
K
A
K
K
D
D
T
D
D
E
I
A
K
Y
Site 14
Y100
T
D
D
E
I
A
K
Y
D
G
K
W
E
V
E
Site 15
S112
E
V
E
E
M
K
E
S
K
L
P
G
D
K
G
Site 16
S132
R
A
K
H
H
A
I
S
A
K
L
N
K
P
F
Site 17
T143
N
K
P
F
L
F
D
T
K
P
L
I
V
Q
Y
Site 18
Y150
T
K
P
L
I
V
Q
Y
E
V
N
F
Q
N
G
Site 19
T171
Y
V
K
L
L
S
K
T
P
E
L
N
L
D
Q
Site 20
Y185
Q
F
H
D
K
T
P
Y
T
I
M
F
G
P
D
Site 21
T186
F
H
D
K
T
P
Y
T
I
M
F
G
P
D
K
Site 22
Y198
P
D
K
C
G
E
D
Y
K
L
H
F
I
F
R
Site 23
T211
F
R
H
K
N
P
K
T
G
I
Y
E
E
K
H
Site 24
Y214
K
N
P
K
T
G
I
Y
E
E
K
H
A
K
R
Site 25
T228
R
P
D
A
D
L
K
T
Y
F
T
D
K
K
T
Site 26
Y229
P
D
A
D
L
K
T
Y
F
T
D
K
K
T
H
Site 27
T231
A
D
L
K
T
Y
F
T
D
K
K
T
H
L
Y
Site 28
T235
T
Y
F
T
D
K
K
T
H
L
Y
T
L
I
L
Site 29
Y238
T
D
K
K
T
H
L
Y
T
L
I
L
N
P
D
Site 30
S259
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Site 31
T267
G
N
L
L
N
D
M
T
P
P
V
N
P
S
R
Site 32
Y330
W
L
D
D
E
P
E
Y
V
P
D
P
D
A
E
Site 33
Y379
P
V
I
D
N
P
N
Y
K
G
K
W
K
P
P
Site 34
S392
P
P
M
I
D
N
P
S
Y
Q
G
I
W
K
P
Site 35
Y393
P
M
I
D
N
P
S
Y
Q
G
I
W
K
P
R
Site 36
S431
L
E
L
W
S
M
T
S
D
I
F
F
D
N
F
Site 37
T509
C
C
S
G
K
K
Q
T
S
G
M
E
Y
K
K
Site 38
S510
C
S
G
K
K
Q
T
S
G
M
E
Y
K
K
T
Site 39
Y514
K
Q
T
S
G
M
E
Y
K
K
T
D
A
P
Q
Site 40
T517
S
G
M
E
Y
K
K
T
D
A
P
Q
P
D
V
Site 41
S554
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
G
Site 42
T562
D
A
E
E
D
G
G
T
V
S
Q
E
E
E
D
Site 43
S564
E
E
D
G
G
T
V
S
Q
E
E
E
D
R
K
Site 44
S583
E
D
E
I
L
N
R
S
P
R
N
R
K
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation