KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACP1
Full Name:
Low molecular weight phosphotyrosine protein phosphatase
Alias:
Acid phosphatase 1; Acid phosphatase 1, soluble; Adipocyte acid phosphatase; Lmwptp; LMW-PTP; LMW-PTPase; Low molecular weight cytosolic acid phosphatase; PPAC; PTPase; Red cell acid phosphatase 1
Type:
EC 3.1.3.48; EC 3.1.3.2; Cofactor and Vitamin Metabolism - riboflavin; Phosphatase (non-protein); Protein phosphatase, tyrosine (non-receptor)
Mass (Da):
18042
Number AA:
158
UniProt ID:
P24666
International Prot ID:
IPI00218847
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0003993
GO:0042802
GO:0004726
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
C
L
G
N
I
C
R
S
P
I
A
E
A
V
F
Site 2
T32
A
V
F
R
K
L
V
T
D
Q
N
I
S
E
N
Site 3
S44
S
E
N
W
R
V
D
S
A
A
T
S
G
Y
E
Site 4
S48
R
V
D
S
A
A
T
S
G
Y
E
I
G
N
P
Site 5
Y50
D
S
A
A
T
S
G
Y
E
I
G
N
P
P
D
Site 6
Y58
E
I
G
N
P
P
D
Y
R
G
Q
S
C
M
K
Site 7
S62
P
P
D
Y
R
G
Q
S
C
M
K
R
H
G
I
Site 8
S72
K
R
H
G
I
P
M
S
H
V
A
R
Q
I
T
Site 9
T79
S
H
V
A
R
Q
I
T
K
E
D
F
A
T
F
Site 10
Y88
E
D
F
A
T
F
D
Y
I
L
C
M
D
E
S
Site 11
S104
L
R
D
L
N
R
K
S
N
Q
V
K
T
C
K
Site 12
S119
A
K
I
E
L
L
G
S
Y
D
P
Q
K
Q
L
Site 13
Y120
K
I
E
L
L
G
S
Y
D
P
Q
K
Q
L
I
Site 14
Y132
Q
L
I
I
E
D
P
Y
Y
G
N
D
S
D
F
Site 15
Y133
L
I
I
E
D
P
Y
Y
G
N
D
S
D
F
E
Site 16
S137
D
P
Y
Y
G
N
D
S
D
F
E
T
V
Y
Q
Site 17
T141
G
N
D
S
D
F
E
T
V
Y
Q
Q
C
V
R
Site 18
Y143
D
S
D
F
E
T
V
Y
Q
Q
C
V
R
C
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation