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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FSH receptor
Full Name:
Follicle-stimulating hormone receptor
Alias:
Follitropin receptor
Type:
G protein-coupled 7TM receptor
Mass (Da):
78295
Number AA:
695
UniProt ID:
P23945
International Prot ID:
IPI00303575
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004963
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007292
GO:0007283
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
L
C
Q
E
S
K
V
T
E
I
P
S
D
L
P
Site 2
S42
S
K
V
T
E
I
P
S
D
L
P
R
N
A
I
Site 3
S78
D
L
E
K
I
E
I
S
Q
N
D
V
L
E
V
Site 4
Y110
E
K
A
N
N
L
L
Y
I
N
P
E
A
F
Q
Site 5
Y124
Q
N
L
P
N
L
Q
Y
L
L
I
S
N
T
G
Site 6
T130
Q
Y
L
L
I
S
N
T
G
I
K
H
L
P
D
Site 7
S143
P
D
V
H
K
I
H
S
L
Q
K
V
L
L
D
Site 8
T159
Q
D
N
I
N
I
H
T
I
E
R
N
S
F
V
Site 9
S164
I
H
T
I
E
R
N
S
F
V
G
L
S
F
E
Site 10
S201
Q
L
D
E
L
N
L
S
D
N
N
N
L
E
E
Site 11
S232
I
S
R
T
R
I
H
S
L
P
S
Y
G
L
E
Site 12
Y236
R
I
H
S
L
P
S
Y
G
L
E
N
L
K
K
Site 13
S248
L
K
K
L
R
A
R
S
T
Y
N
L
K
K
L
Site 14
T249
K
K
L
R
A
R
S
T
Y
N
L
K
K
L
P
Site 15
Y250
K
L
R
A
R
S
T
Y
N
L
K
K
L
P
T
Site 16
S295
L
H
P
I
C
N
K
S
I
L
R
Q
E
V
D
Site 17
Y303
I
L
R
Q
E
V
D
Y
M
T
Q
T
R
G
Q
Site 18
T305
R
Q
E
V
D
Y
M
T
Q
T
R
G
Q
R
S
Site 19
S313
Q
T
R
G
Q
R
S
S
L
A
E
D
N
E
S
Site 20
S320
S
L
A
E
D
N
E
S
S
Y
S
R
G
F
D
Site 21
Y322
A
E
D
N
E
S
S
Y
S
R
G
F
D
M
T
Site 22
S323
E
D
N
E
S
S
Y
S
R
G
F
D
M
T
Y
Site 23
Y330
S
R
G
F
D
M
T
Y
T
E
F
D
Y
D
L
Site 24
Y335
M
T
Y
T
E
F
D
Y
D
L
C
N
E
V
V
Site 25
T345
C
N
E
V
V
D
V
T
C
S
P
K
P
D
A
Site 26
S347
E
V
V
D
V
T
C
S
P
K
P
D
A
F
N
Site 27
T395
T
T
S
Q
Y
K
L
T
V
P
R
F
L
M
C
Site 28
T425
I
A
S
V
D
I
H
T
K
S
Q
Y
H
N
Y
Site 29
T470
I
T
L
E
R
W
H
T
I
T
H
A
M
Q
L
Site 30
T472
L
E
R
W
H
T
I
T
H
A
M
Q
L
D
C
Site 31
S563
V
R
N
P
N
I
V
S
S
S
S
D
T
R
I
Site 32
S564
R
N
P
N
I
V
S
S
S
S
D
T
R
I
A
Site 33
S566
P
N
I
V
S
S
S
S
D
T
R
I
A
K
R
Site 34
T568
I
V
S
S
S
S
D
T
R
I
A
K
R
M
A
Site 35
T656
M
Q
A
Q
I
Y
R
T
E
T
S
S
T
V
H
Site 36
T658
A
Q
I
Y
R
T
E
T
S
S
T
V
H
N
T
Site 37
S660
I
Y
R
T
E
T
S
S
T
V
H
N
T
H
P
Site 38
T661
Y
R
T
E
T
S
S
T
V
H
N
T
H
P
R
Site 39
T665
T
S
S
T
V
H
N
T
H
P
R
N
G
H
C
Site 40
S673
H
P
R
N
G
H
C
S
S
A
P
R
V
T
N
Site 41
S674
P
R
N
G
H
C
S
S
A
P
R
V
T
N
G
Site 42
T679
C
S
S
A
P
R
V
T
N
G
S
T
Y
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation