PhosphoNET

           
Protein Info 
   
Short Name:  SFPQ
Full Name:  Splicing factor, proline- and glutamine-rich
Alias:  DNA-binding P52/P100 complex, 100 kDa subunit; Polypyrimidine tract binding protein associated; Polypyrimidine tract- binding protein-associated splicing factor; Polypyrimidine tract-binding protein-associated-splicing factor; PTB-associated splicing factor; Splicing factor proline/glutamine rich(polypyrimidine tract binding protein associated); Splicing factor proline/glutamine-rich; Splicing factor, proline-and glutamine-rich
Type:  Nuclear receptor co-regulator; RNA binding protein
Mass (Da):  76149
Number AA:  707
UniProt ID:  P23246
International Prot ID:  IPI00010740
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016363  GO:0016363  GO:0043226 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003723  GO:0000166 PhosphoSite+ KinaseNET
Biological Process:  GO:0006310  GO:0006281  GO:0008380 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MSRDRFRSRGGGGGG
Site 2S33GGLHDFRSPPPGMGL
Site 3S54MGPGPGQSGPKPPIP
Site 4S106PPPPPQDSSKPVVAQ
Site 5S107PPPPQDSSKPVVAQG
Site 6S123GPAPGVGSAPPASSS
Site 7S128VGSAPPASSSAPPAT
Site 8S129GSAPPASSSAPPATP
Site 9S130SAPPASSSAPPATPP
Site 10T135SSSAPPATPPTSGAP
Site 11T138APPATPPTSGAPPGS
Site 12S139PPATPPTSGAPPGSG
Site 13S145TSGAPPGSGPGPTPT
Site 14T150PGSGPGPTPTPPPAV
Site 15T152SGPGPTPTPPPAVTS
Site 16T158PTPPPAVTSAPPGAP
Site 17S159TPPPAVTSAPPGAPP
Site 18T168PPGAPPPTPPSSGVP
Site 19S171APPPTPPSSGVPTTP
Site 20S172PPPTPPSSGVPTTPP
Site 21T176PPSSGVPTTPPQAGG
Site 22T177PSSGVPTTPPQAGGP
Site 23S225PGGGPGLSTPGGHPK
Site 24T226GGGPGLSTPGGHPKP
Site 25Y251GRQHHPPYHQQHHQG
Site 26S268PGGPGGRSEEKISDS
Site 27S273GRSEEKISDSEGFKA
Site 28S275SEEKISDSEGFKANL
Site 29S283EGFKANLSLLRRPGE
Site 30T292LRRPGEKTYTQRCRL
Site 31Y293RRPGEKTYTQRCRLF
Site 32T294RPGEKTYTQRCRLFV
Site 33T309GNLPADITEDEFKRL
Site 34Y320FKRLFAKYGEPGEVF
Site 35T355AKAELDDTPMRGRQL
Site 36S379ALSVRNLSPYVSNEL
Site 37Y381SVRNLSPYVSNELLE
Site 38S383RNLSPYVSNELLEEA
Site 39S392ELLEEAFSQFGPIER
Site 40S410IVDDRGRSTGKGIVE
Site 41T411VDDRGRSTGKGIVEF
Site 42S432RKAFERCSEGVFLLT
Site 43Y470LAQKNPMYQKERETP
Site 44T476MYQKERETPPRFAQH
Site 45T485PRFAQHGTFEYEYSQ
Site 46Y488AQHGTFEYEYSQRWK
Site 47Y490HGTFEYEYSQRWKSL
Site 48S491GTFEYEYSQRWKSLD
Site 49S496EYSQRWKSLDEMEKQ
Site 50S521DAKDKLESEMEDAYH
Site 51Y527ESEMEDAYHEHQANL
Site 52S596MRRQREESYSRMGYM
Site 53Y597RRQREESYSRMGYMD
Site 54S598RQREESYSRMGYMDP
Site 55Y602ESYSRMGYMDPRERD
Site 56Y624AMNMGDPYGSGGQKF
Site 57S626NMGDPYGSGGQKFPP
Site 58Y642GGGGGIGYEANPGVP
Site 59T652NPGVPPATMSGSMMG
Site 60S654GVPPATMSGSMMGSD
Site 61S656PPATMSGSMMGSDMR
Site 62S660MSGSMMGSDMRTERF
Site 63T664MMGSDMRTERFGQGG
Site 64T687PRGMGPGTPAGYGRG
Site 65Y691GPGTPAGYGRGREEY
Site 66Y698YGRGREEYEGPNKKP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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