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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LMNB1
Full Name:
Lamin-B1
Alias:
LAM1; LMN2; LMNB; LMNB1 protein
Type:
Cytoskeletal protein
Mass (Da):
66408
Number AA:
586
UniProt ID:
P20700
International Prot ID:
IPI00217975
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005638
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
A
T
A
T
P
V
P
P
R
Site 2
T5
_
_
_
M
A
T
A
T
P
V
P
P
R
M
G
Site 3
S13
P
V
P
P
R
M
G
S
R
A
G
G
P
T
T
Site 4
T19
G
S
R
A
G
G
P
T
T
P
L
S
P
T
R
Site 5
T20
S
R
A
G
G
P
T
T
P
L
S
P
T
R
L
Site 6
S23
G
G
P
T
T
P
L
S
P
T
R
L
S
R
L
Site 7
T25
P
T
T
P
L
S
P
T
R
L
S
R
L
Q
E
Site 8
S28
P
L
S
P
T
R
L
S
R
L
Q
E
K
E
E
Site 9
Y46
L
N
D
R
L
A
V
Y
I
D
K
V
R
S
L
Site 10
S52
V
Y
I
D
K
V
R
S
L
E
T
E
N
S
A
Site 11
S58
R
S
L
E
T
E
N
S
A
L
Q
L
Q
V
T
Site 12
T65
S
A
L
Q
L
Q
V
T
E
R
E
E
V
R
G
Site 13
T76
E
V
R
G
R
E
L
T
G
L
K
A
L
Y
E
Site 14
T84
G
L
K
A
L
Y
E
T
E
L
A
D
A
R
R
Site 15
T96
A
R
R
A
L
D
D
T
A
R
E
R
A
K
L
Site 16
Y138
A
Q
I
K
L
R
E
Y
E
A
A
L
N
S
K
Site 17
S158
T
A
L
G
D
K
K
S
L
E
G
D
L
E
D
Site 18
T188
K
K
Q
L
A
D
E
T
L
L
K
V
D
L
E
Site 19
S200
D
L
E
N
R
C
Q
S
L
T
E
D
L
E
F
Site 20
T202
E
N
R
C
Q
S
L
T
E
D
L
E
F
R
K
Site 21
S210
E
D
L
E
F
R
K
S
M
Y
E
E
E
I
N
Site 22
Y212
L
E
F
R
K
S
M
Y
E
E
E
I
N
E
T
Site 23
T219
Y
E
E
E
I
N
E
T
R
R
K
H
E
T
R
Site 24
T225
E
T
R
R
K
H
E
T
R
L
V
E
V
D
S
Site 25
S232
T
R
L
V
E
V
D
S
G
R
Q
I
E
Y
E
Site 26
Y260
H
D
A
Q
V
R
L
Y
K
E
E
L
E
Q
T
Site 27
T267
Y
K
E
E
L
E
Q
T
Y
H
A
K
L
E
N
Site 28
Y268
K
E
E
L
E
Q
T
Y
H
A
K
L
E
N
A
Site 29
S278
K
L
E
N
A
R
L
S
S
E
M
N
T
S
T
Site 30
S279
L
E
N
A
R
L
S
S
E
M
N
T
S
T
V
Site 31
T283
R
L
S
S
E
M
N
T
S
T
V
N
S
A
R
Site 32
S284
L
S
S
E
M
N
T
S
T
V
N
S
A
R
E
Site 33
T285
S
S
E
M
N
T
S
T
V
N
S
A
R
E
E
Site 34
S288
M
N
T
S
T
V
N
S
A
R
E
E
L
M
E
Site 35
S296
A
R
E
E
L
M
E
S
R
M
R
I
E
S
L
Site 36
S302
E
S
R
M
R
I
E
S
L
S
S
Q
L
S
N
Site 37
S304
R
M
R
I
E
S
L
S
S
Q
L
S
N
L
Q
Site 38
S305
M
R
I
E
S
L
S
S
Q
L
S
N
L
Q
K
Site 39
S308
E
S
L
S
S
Q
L
S
N
L
Q
K
E
S
R
Site 40
S335
L
A
K
E
K
D
N
S
R
R
M
L
T
D
K
Site 41
T340
D
N
S
R
R
M
L
T
D
K
E
R
E
M
A
Site 42
Y360
M
Q
Q
Q
L
N
D
Y
E
Q
L
L
D
V
K
Site 43
S375
L
A
L
D
M
E
I
S
A
Y
R
K
L
L
E
Site 44
Y377
L
D
M
E
I
S
A
Y
R
K
L
L
E
G
E
Site 45
S391
E
E
E
R
L
K
L
S
P
S
P
S
S
R
V
Site 46
S393
E
R
L
K
L
S
P
S
P
S
S
R
V
T
V
Site 47
S395
L
K
L
S
P
S
P
S
S
R
V
T
V
S
R
Site 48
S396
K
L
S
P
S
P
S
S
R
V
T
V
S
R
A
Site 49
T399
P
S
P
S
S
R
V
T
V
S
R
A
S
S
S
Site 50
S401
P
S
S
R
V
T
V
S
R
A
S
S
S
R
S
Site 51
S404
R
V
T
V
S
R
A
S
S
S
R
S
V
R
T
Site 52
S405
V
T
V
S
R
A
S
S
S
R
S
V
R
T
T
Site 53
S406
T
V
S
R
A
S
S
S
R
S
V
R
T
T
R
Site 54
S408
S
R
A
S
S
S
R
S
V
R
T
T
R
G
K
Site 55
T411
S
S
S
R
S
V
R
T
T
R
G
K
R
K
R
Site 56
T412
S
S
R
S
V
R
T
T
R
G
K
R
K
R
V
Site 57
S424
K
R
V
D
V
E
E
S
E
A
S
S
S
V
S
Site 58
S427
D
V
E
E
S
E
A
S
S
S
V
S
I
S
H
Site 59
S428
V
E
E
S
E
A
S
S
S
V
S
I
S
H
S
Site 60
S429
E
E
S
E
A
S
S
S
V
S
I
S
H
S
A
Site 61
S431
S
E
A
S
S
S
V
S
I
S
H
S
A
S
A
Site 62
S433
A
S
S
S
V
S
I
S
H
S
A
S
A
T
G
Site 63
S435
S
S
V
S
I
S
H
S
A
S
A
T
G
N
V
Site 64
T439
I
S
H
S
A
S
A
T
G
N
V
C
I
E
E
Site 65
S460
F
I
R
L
K
N
T
S
E
Q
D
Q
P
M
G
Site 66
T478
M
I
R
K
I
G
D
T
S
V
S
Y
K
Y
T
Site 67
S479
I
R
K
I
G
D
T
S
V
S
Y
K
Y
T
S
Site 68
S481
K
I
G
D
T
S
V
S
Y
K
Y
T
S
R
Y
Site 69
Y482
I
G
D
T
S
V
S
Y
K
Y
T
S
R
Y
V
Site 70
Y484
D
T
S
V
S
Y
K
Y
T
S
R
Y
V
L
K
Site 71
T485
T
S
V
S
Y
K
Y
T
S
R
Y
V
L
K
A
Site 72
Y488
S
Y
K
Y
T
S
R
Y
V
L
K
A
G
Q
T
Site 73
S534
V
K
V
I
L
K
N
S
Q
G
E
E
V
A
Q
Site 74
T544
E
E
V
A
Q
R
S
T
V
F
K
T
T
I
P
Site 75
T548
Q
R
S
T
V
F
K
T
T
I
P
E
E
E
E
Site 76
T549
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Site 77
T575
E
L
F
H
Q
Q
G
T
P
R
A
S
N
R
S
Site 78
S579
Q
Q
G
T
P
R
A
S
N
R
S
C
A
I
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation