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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
M6PR
Full Name:
Cation-dependent mannose-6-phosphate receptor
Alias:
46 kDa mannose 6-phosphate receptor
Type:
Mass (Da):
30993
Number AA:
277
UniProt ID:
P20645
International Prot ID:
IPI00025049
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005887
GO:0005764
Uniprot
OncoNet
Molecular Function:
GO:0005537
GO:0015578
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008333
GO:0015761
GO:0006898
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
L
A
V
A
V
R
E
S
W
Q
T
E
E
K
T
Site 2
T27
A
V
R
E
S
W
Q
T
E
E
K
T
C
D
L
Site 3
S59
L
K
P
L
F
N
K
S
F
E
S
T
V
G
Q
Site 4
S62
L
F
N
K
S
F
E
S
T
V
G
Q
G
S
D
Site 5
T63
F
N
K
S
F
E
S
T
V
G
Q
G
S
D
T
Site 6
S68
E
S
T
V
G
Q
G
S
D
T
Y
I
Y
I
F
Site 7
Y73
Q
G
S
D
T
Y
I
Y
I
F
R
V
C
R
E
Site 8
S86
R
E
A
G
N
H
T
S
G
A
G
L
V
Q
I
Site 9
S96
G
L
V
Q
I
N
K
S
N
G
K
E
T
V
V
Site 10
T101
N
K
S
N
G
K
E
T
V
V
G
R
L
N
E
Site 11
Y122
S
N
W
I
M
L
I
Y
K
G
G
D
E
Y
D
Site 12
Y128
I
Y
K
G
G
D
E
Y
D
N
H
C
G
K
E
Site 13
T149
M
I
S
C
N
R
H
T
L
A
D
N
F
N
P
Site 14
S158
A
D
N
F
N
P
V
S
E
E
R
G
K
V
Q
Site 15
Y169
G
K
V
Q
D
C
F
Y
L
F
E
M
D
S
S
Site 16
S180
M
D
S
S
L
A
C
S
P
E
I
S
H
L
S
Site 17
S246
G
C
D
F
V
C
R
S
K
P
R
N
V
P
A
Site 18
Y255
P
R
N
V
P
A
A
Y
R
G
V
G
D
D
Q
Site 19
S267
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation