KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CK2-A2
Full Name:
Casein kinase II subunit alpha'
Alias:
Casein kinase 2, alpha prime polypeptide; Casein kinase II, alpha\' chain; CK II; CK2A2; CK2-alpha2; CSK22; CSNK2A1; CSNK2A2; EC 2.7.1.37; EC 2.7.11.; Kinase CK2-alpha2
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.1.37; EC 2.7.11.1; Other group; CK2 family
Mass (Da):
41213
Number AA:
350
UniProt ID:
P19784
International Prot ID:
IPI00020602
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0047485
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
CK2pSelectide - CK2a2 (CSNK2A2) protein kinase substrate peptide - Powder PE-04AXK75#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AXK75
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
A
G
S
R
A
R
V
Y
A
E
V
N
S
L
R
Site 2
S18
R
V
Y
A
E
V
N
S
L
R
S
R
E
Y
W
Site 3
S21
A
E
V
N
S
L
R
S
R
E
Y
W
D
Y
E
Site 4
Y24
N
S
L
R
S
R
E
Y
W
D
Y
E
A
H
V
Site 5
Y27
R
S
R
E
Y
W
D
Y
E
A
H
V
P
S
W
Site 6
Y40
S
W
G
N
Q
D
D
Y
Q
L
V
R
K
L
G
Site 7
Y51
R
K
L
G
R
G
K
Y
S
E
V
F
E
A
I
Site 8
S52
K
L
G
R
G
K
Y
S
E
V
F
E
A
I
N
Site 9
T101
N
I
I
K
L
I
D
T
V
K
D
P
V
S
K
Site 10
S107
D
T
V
K
D
P
V
S
K
T
P
A
L
V
F
Site 11
T109
V
K
D
P
V
S
K
T
P
A
L
V
F
E
Y
Site 12
Y126
N
T
D
F
K
Q
L
Y
Q
I
L
T
D
F
D
Site 13
T130
K
Q
L
Y
Q
I
L
T
D
F
D
I
R
F
Y
Site 14
Y137
T
D
F
D
I
R
F
Y
M
Y
E
L
L
K
A
Site 15
Y189
F
Y
H
P
A
Q
E
Y
N
V
R
V
A
S
R
Site 16
S195
E
Y
N
V
R
V
A
S
R
Y
F
K
G
P
E
Site 17
Y197
N
V
R
V
A
S
R
Y
F
K
G
P
E
L
L
Site 18
Y207
G
P
E
L
L
V
D
Y
Q
M
Y
D
Y
S
L
Site 19
Y210
L
L
V
D
Y
Q
M
Y
D
Y
S
L
D
M
W
Site 20
Y212
V
D
Y
Q
M
Y
D
Y
S
L
D
M
W
S
L
Site 21
Y240
F
F
H
G
Q
D
N
Y
D
Q
L
V
R
I
A
Site 22
Y256
V
L
G
T
E
E
L
Y
G
Y
L
K
K
Y
H
Site 23
Y258
G
T
E
E
L
Y
G
Y
L
K
K
Y
H
I
D
Site 24
Y262
L
Y
G
Y
L
K
K
Y
H
I
D
L
D
P
H
Site 25
S288
R
W
E
N
F
I
H
S
E
N
R
H
L
V
S
Site 26
S295
S
E
N
R
H
L
V
S
P
E
A
L
D
L
L
Site 27
T315
Y
D
H
Q
Q
R
L
T
A
K
E
A
M
E
H
Site 28
Y324
K
E
A
M
E
H
P
Y
F
Y
P
V
V
K
E
Site 29
Y326
A
M
E
H
P
Y
F
Y
P
V
V
K
E
Q
S
Site 30
S343
C
A
D
N
A
V
L
S
S
G
L
T
A
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation