PhosphoNET

           
Protein Info 
   
Short Name:  ATF4
Full Name:  Cyclic AMP-dependent transcription factor ATF-4
Alias:  Activating transcription factor 4
Type:  Transcription protein
Mass (Da):  38590
Number AA:  351
UniProt ID:  P18848
International Prot ID:  IPI00002503
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0046983  GO:0043565  GO:0003704 PhosphoSite+ KinaseNET
Biological Process:  GO:0006520  GO:0006094  GO:0045944 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30SGLGAEESLGLLDDY
Site 2S51FKPHGFSSDKAKAGS
Site 3S69LAVDGLVSPSNNSKE
Site 4S74LVSPSNNSKEDAFSG
Site 5S80NSKEDAFSGTDWMLE
Site 6T114TMPDDLLTTLDDTCD
Site 7T137TNKQPPQTVNPIGHL
Site 8S147PIGHLPESLTKPDQV
Site 9T149GHLPESLTKPDQVAP
Site 10S171PLSPGVLSSTPDHSF
Site 11S172LSPGVLSSTPDHSFS
Site 12T173SPGVLSSTPDHSFSL
Site 13S177LSSTPDHSFSLELGS
Site 14S179STPDHSFSLELGSEV
Site 15S184SFSLELGSEVDITEG
Site 16T189LGSEVDITEGDRKPD
Site 17Y197EGDRKPDYTAYVAMI
Site 18T198GDRKPDYTAYVAMIP
Site 19Y200RKPDYTAYVAMIPQC
Site 20T213QCIKEEDTPSDNDSG
Site 21S215IKEEDTPSDNDSGIC
Site 22S219DTPSDNDSGICMSPE
Site 23S224NDSGICMSPESYLGS
Site 24S227GICMSPESYLGSPQH
Site 25Y228ICMSPESYLGSPQHS
Site 26S231SPESYLGSPQHSPST
Site 27S235YLGSPQHSPSTRGSP
Site 28S237GSPQHSPSTRGSPNR
Site 29S241HSPSTRGSPNRSLPS
Site 30S245TRGSPNRSLPSPGVL
Site 31S248SPNRSLPSPGVLCGS
Site 32S255SPGVLCGSARPKPYD
Site 33Y261GSARPKPYDPPGEKM
Site 34T290KKMEQNKTAATRYRQ
Site 35S326ALKERADSLAKEIQY
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation