PhosphoNET

           
Protein Info 
   
Short Name:  RDBP
Full Name:  Negative elongation factor E
Alias:  D6S45; Negative elongation factor E;RNA-binding protein RD; NELFE; NELF-E; NLFE; RD; RD protein; RD RNA binding protein; RDP
Type:  Transcription, coactivator/corepressor
Mass (Da):  43240
Number AA:  380
UniProt ID:  P18615
International Prot ID:  IPI00000858
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005739  GO:0005654  GO:0005730 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0045449  GO:0006350  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9LVIPPGLSEEEEALQ
Site 2S36LLALKKQSSSSTTSQ
Site 3S37LALKKQSSSSTTSQG
Site 4S38ALKKQSSSSTTSQGG
Site 5S39LKKQSSSSTTSQGGV
Site 6T40KKQSSSSTTSQGGVK
Site 7T41KQSSSSTTSQGGVKR
Site 8S42QSSSSTTSQGGVKRS
Site 9S49SQGGVKRSLSEQPVM
Site 10S51GGVKRSLSEQPVMDT
Site 11S71QAKQLVKSGAISAIK
Site 12S84IKAETKNSGFKRSRT
Site 13S89KNSGFKRSRTLEGKL
Site 14T91SGFKRSRTLEGKLKD
Site 15T106PEKGPVPTFQPFQRS
Site 16S113TFQPFQRSISADDDL
Site 17S115QPFQRSISADDDLQE
Site 18S123ADDDLQESSRRPQRK
Site 19S124DDDLQESSRRPQRKS
Site 20S131SRRPQRKSLYESFVS
Site 21Y133RPQRKSLYESFVSSS
Site 22S135QRKSLYESFVSSSDR
Site 23S138SLYESFVSSSDRLRE
Site 24S139LYESFVSSSDRLREL
Site 25S140YESFVSSSDRLRELG
Site 26S165AGDGPPRSFDWGYEE
Site 27Y170PRSFDWGYEERSGAH
Site 28S174DWGYEERSGAHSSAS
Site 29S178EERSGAHSSASPPRS
Site 30S179ERSGAHSSASPPRSR
Site 31S181SGAHSSASPPRSRSR
Site 32S185SSASPPRSRSRDRSH
Site 33S187ASPPRSRSRDRSHER
Site 34S191RSRSRDRSHERNRDR
Site 35S249REGPFRRSDSFPERR
Site 36S251GPFRRSDSFPERRAP
Site 37Y265PRKGNTLYVYGEDMT
Site 38Y267KGNTLYVYGEDMTPT
Site 39T272YVYGEDMTPTLLRGA
Site 40T274YGEDMTPTLLRGAFS
Site 41S281TLLRGAFSPFGNIID
Site 42Y302RNCAFVTYEKMESAD
Site 43S307VTYEKMESADQAVAE
Site 44T340QPMLDAATGKSVWGS
Site 45S347TGKSVWGSLAVQNSP
Site 46S353GSLAVQNSPKGCHRD
Site 47T363GCHRDKRTQIVYSDD
Site 48Y367DKRTQIVYSDDVYKE
Site 49S368KRTQIVYSDDVYKEN
Site 50Y372IVYSDDVYKENLVDG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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