PhosphoNET

           
Protein Info 
   
Short Name:  LGALS3
Full Name:  Galectin-3
Alias:  35 kDa lectin; Carbohydrate binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin 3; GALIG; IgE-binding protein; L-31; L-34 galactoside-binding lectin; Laminin-binding protein; Lectin L-29; Lectin, galactoside-binding, soluble, 3; LEG3; LGALS2; MAC2; MAC-2; MAC-2 antigen
Type:  Cell surface protein
Mass (Da):  26152
Number AA:  250
UniProt ID:  P17931
International Prot ID:  IPI00465431
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005743  GO:0005634  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0019863  GO:0005529   PhosphoSite+ KinaseNET
Biological Process:  GO:0030154     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MADNFSLHDALSG
Site 2S12FSLHDALSGSGNPNP
Site 3S14LHDALSGSGNPNPQG
Site 4Y36QPAGAGGYPGASYPG
Site 5S40AGGYPGASYPGAYPG
Site 6Y41GGYPGASYPGAYPGQ
Site 7Y45GASYPGAYPGQAPPG
Site 8Y54GQAPPGAYPGQAPPG
Site 9Y63GQAPPGAYPGAPGAY
Site 10Y79GAPAPGVYPGPPSGP
Site 11S84GVYPGPPSGPGAYPS
Site 12Y89PPSGPGAYPSSGQPS
Site 13S91SGPGAYPSSGQPSAT
Site 14S92GPGAYPSSGQPSATG
Site 15S96YPSSGQPSATGAYPA
Site 16Y101QPSATGAYPATGPYG
Site 17Y107AYPATGPYGAPAGPL
Site 18Y118AGPLIVPYNLPLPGG
Site 19T133VVPRMLITILGTVKP
Site 20T175RRVIVCNTKLDNNWG
Site 21S188WGREERQSVFPFESG
Site 22S194QSVFPFESGKPFKIQ
Site 23Y221NDAHLLQYNHRVKKL
Site 24S232VKKLNEISKLGISGD
Site 25S237EISKLGISGDIDLTS
Site 26Y247IDLTSASYTMI____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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