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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PECAM-1
Full Name:
Platelet endothelial cell adhesion molecule
Alias:
CD31; CD31 antigen; EndoCAM; PEC1; PECA1; PECAM; PECAM1; platelet/endothelial cell adhesion molecule
Type:
Cell surface protein
Mass (Da):
82536
Number AA:
738
UniProt ID:
P16284
International Prot ID:
IPI00295618
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0008037
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y290
R
H
G
N
K
A
V
Y
S
V
M
A
M
V
E
Site 2
S308
N
Y
T
C
K
V
E
S
S
R
I
S
K
V
S
Site 3
S309
Y
T
C
K
V
E
S
S
R
I
S
K
V
S
S
Site 4
T364
F
T
I
Q
K
E
D
T
I
V
S
Q
T
Q
D
Site 5
S448
S
Y
Q
L
L
K
T
S
K
V
L
E
N
S
T
Site 6
S583
N
R
A
N
H
A
S
S
V
P
R
S
K
I
L
Site 7
S587
H
A
S
S
V
P
R
S
K
I
L
T
V
R
V
Site 8
Y623
L
I
I
A
A
K
C
Y
F
L
R
K
A
K
A
Site 9
S638
K
Q
M
P
V
E
M
S
R
P
A
V
P
L
L
Site 10
S647
P
A
V
P
L
L
N
S
N
N
E
K
M
S
D
Site 11
S653
N
S
N
N
E
K
M
S
D
P
N
M
E
A
N
Site 12
Y663
N
M
E
A
N
S
H
Y
G
H
N
D
D
V
R
Site 13
S686
D
N
K
E
P
L
N
S
D
V
Q
Y
T
E
V
Site 14
Y690
P
L
N
S
D
V
Q
Y
T
E
V
Q
V
S
S
Site 15
T691
L
N
S
D
V
Q
Y
T
E
V
Q
V
S
S
A
Site 16
S696
Q
Y
T
E
V
Q
V
S
S
A
E
S
H
K
D
Site 17
S700
V
Q
V
S
S
A
E
S
H
K
D
L
G
K
K
Site 18
T709
K
D
L
G
K
K
D
T
E
T
V
Y
S
E
V
Site 19
T711
L
G
K
K
D
T
E
T
V
Y
S
E
V
R
K
Site 20
Y713
K
K
D
T
E
T
V
Y
S
E
V
R
K
A
V
Platelet endothelial cell adhesion molecule Y713 phosphosite-specific antibody AB-PN523#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN523#Platelet endothelial cell adhesion molecule (E710-V716, human) pY713 phosphopeptide - Powder PE-04AEZ99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEZ99
Site 21
S714
K
D
T
E
T
V
Y
S
E
V
R
K
A
V
P
Site 22
Y728
P
D
A
V
E
S
R
Y
S
R
T
E
G
S
L
Site 23
S729
D
A
V
E
S
R
Y
S
R
T
E
G
S
L
D
Site 24
S734
R
Y
S
R
T
E
G
S
L
D
G
T
_
_
_
Site 25
T738
T
E
G
S
L
D
G
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation