PhosphoNET

           
Protein Info 
   
Short Name:  MUC1
Full Name:  Mucin-1
Alias:  Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227; EMA; Episialin; H23AG; MUC-1; mucin 1; Mucin 1 precursor; mucin 1, cell surface associated; mucin 1, transmembrane; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen; Tumor-associated mucin
Type:  Adhesion; Nuclear receptor co-regulator; Actin binding protein
Mass (Da):  122072
Number AA:  1255
UniProt ID:  P15941
International Prot ID:  IPI00013955
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005576  GO:0005887 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S44TSATQRSSVPSSTEK
Site 2Y1191CQCRRKNYGQLDIFP
Site 3T1202DIFPARDTYHPMSEY
Site 4Y1203IFPARDTYHPMSEYP
Site 5S1207RDTYHPMSEYPTYHT
Site 6Y1209TYHPMSEYPTYHTHG
Site 7T1211HPMSEYPTYHTHGRY
Site 8Y1212PMSEYPTYHTHGRYV
Site 9T1214SEYPTYHTHGRYVPP
Site 10Y1218TYHTHGRYVPPSSTD
Site 11S1222HGRYVPPSSTDRSPY
Site 12S1223GRYVPPSSTDRSPYE
Site 13T1224RYVPPSSTDRSPYEK
Site 14S1227PPSSTDRSPYEKVSA
Site 15Y1229SSTDRSPYEKVSAGN
Site 16S1233RSPYEKVSAGNGGSS
Site 17S1240SAGNGGSSLSYTNPA
Site 18S1242GNGGSSLSYTNPAVA
Site 19Y1243NGGSSLSYTNPAVAA
Site 20T1244GGSSLSYTNPAVAAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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