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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATF2
Full Name:
Cyclic AMP-dependent transcription factor ATF-2
Alias:
Activating 2; Activating transcription factor 2; CAMP response element binding protein CRE- BP1; CREB2; CREBP1; CRE-BP1; Cyclic-AMP-dependent ATF-2; HB16; MXBP protein; TREB7
Type:
Transcription protein
Mass (Da):
54537
Number AA:
505
UniProt ID:
P15336
International Prot ID:
IPI00234446
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0046983
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Transcription factor ATF2 T69+T71 phosphosite-specific antibody AB-PN552#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN552#Transcription factor ATF2 (A66-R74, human) pT69+pT71 phosphopeptide - Powder PE-04ARD99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARD99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
F
K
L
H
V
N
S
A
R
Q
Y
K
D
L
Site 2
Y13
H
V
N
S
A
R
Q
Y
K
D
L
W
N
M
S
Site 3
T37
P
G
C
G
Q
R
F
T
N
E
D
H
L
A
V
Site 4
T52
H
K
H
K
H
E
M
T
L
K
F
G
P
A
R
Site 5
S62
F
G
P
A
R
N
D
S
V
I
V
A
D
Q
T
Site 6
T69
S
V
I
V
A
D
Q
T
P
T
P
T
R
F
L
Transcription factor ATF2 T69+T71 phosphosite-specific antibody AB-PN552#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN552#Transcription factor ATF2 (A66-R74, human) pT69+pT71 phosphopeptide - Powder PE-04ARD99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARD99
Site 7
T71
I
V
A
D
Q
T
P
T
P
T
R
F
L
K
N
Transcription factor ATF2 T69+T71 phosphosite-specific antibody AB-PN552#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN552#Transcription factor ATF2 (A66-R74, human) pT69+pT71 phosphopeptide - Powder PE-04ARD99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARD99
Site 8
T73
A
D
Q
T
P
T
P
T
R
F
L
K
N
C
E
Site 9
S90
G
L
F
N
E
L
A
S
P
F
E
N
E
F
K
Site 10
S112
K
K
M
P
L
D
L
S
P
L
A
T
P
I
I
Site 11
T116
L
D
L
S
P
L
A
T
P
I
I
R
S
K
I
Site 12
S121
L
A
T
P
I
I
R
S
K
I
E
E
P
S
V
Site 13
S127
R
S
K
I
E
E
P
S
V
V
E
T
T
H
Q
Site 14
T131
E
E
P
S
V
V
E
T
T
H
Q
D
S
P
L
Site 15
T132
E
P
S
V
V
E
T
T
H
Q
D
S
P
L
P
Site 16
S136
V
E
T
T
H
Q
D
S
P
L
P
H
P
E
S
Site 17
S143
S
P
L
P
H
P
E
S
T
T
S
D
E
K
E
Site 18
S146
P
H
P
E
S
T
T
S
D
E
K
E
V
P
L
Site 19
S161
A
Q
T
A
Q
P
T
S
A
I
V
R
P
A
S
Site 20
S194
Q
A
V
P
S
P
T
S
S
T
V
I
T
Q
A
Site 21
T199
P
T
S
S
T
V
I
T
Q
A
P
S
S
N
R
Site 22
S266
P
G
I
P
G
P
S
S
P
Q
P
V
Q
S
E
Site 23
S272
S
S
P
Q
P
V
Q
S
E
A
K
M
R
L
K
Site 24
T283
M
R
L
K
A
A
L
T
Q
Q
H
P
P
V
T
Site 25
T290
T
Q
Q
H
P
P
V
T
N
G
D
T
V
K
G
Site 26
T294
P
P
V
T
N
G
D
T
V
K
G
H
G
S
G
Site 27
T305
H
G
S
G
L
V
R
T
Q
S
E
E
S
R
P
Site 28
S307
S
G
L
V
R
T
Q
S
E
E
S
R
P
Q
S
Site 29
S310
V
R
T
Q
S
E
E
S
R
P
Q
S
L
Q
Q
Site 30
S314
S
E
E
S
R
P
Q
S
L
Q
Q
P
A
T
S
Site 31
S321
S
L
Q
Q
P
A
T
S
T
T
E
T
P
A
S
Site 32
T323
Q
Q
P
A
T
S
T
T
E
T
P
A
S
P
A
Site 33
T325
P
A
T
S
T
T
E
T
P
A
S
P
A
H
T
Site 34
S328
S
T
T
E
T
P
A
S
P
A
H
T
T
P
Q
Site 35
T332
T
P
A
S
P
A
H
T
T
P
Q
T
Q
S
T
Site 36
T333
P
A
S
P
A
H
T
T
P
Q
T
Q
S
T
S
Site 37
T336
P
A
H
T
T
P
Q
T
Q
S
T
S
G
R
R
Site 38
S338
H
T
T
P
Q
T
Q
S
T
S
G
R
R
R
R
Site 39
S340
T
P
Q
T
Q
S
T
S
G
R
R
R
R
A
A
Site 40
S367
E
R
N
R
A
A
A
S
R
C
R
Q
K
R
K
Site 41
S379
K
R
K
V
W
V
Q
S
L
E
K
K
A
E
D
Site 42
S389
K
K
A
E
D
L
S
S
L
N
G
Q
L
Q
S
Site 43
S396
S
L
N
G
Q
L
Q
S
E
V
T
L
L
R
N
Site 44
S427
V
T
A
M
Q
K
K
S
G
Y
H
T
A
D
K
Site 45
T431
Q
K
K
S
G
Y
H
T
A
D
K
D
D
S
S
Site 46
S437
H
T
A
D
K
D
D
S
S
E
D
I
S
V
P
Site 47
S438
T
A
D
K
D
D
S
S
E
D
I
S
V
P
S
Site 48
S442
D
D
S
S
E
D
I
S
V
P
S
S
P
H
T
Site 49
S446
E
D
I
S
V
P
S
S
P
H
T
E
A
I
Q
Site 50
T449
S
V
P
S
S
P
H
T
E
A
I
Q
H
S
S
Site 51
S455
H
T
E
A
I
Q
H
S
S
V
S
T
S
N
G
Site 52
S456
T
E
A
I
Q
H
S
S
V
S
T
S
N
G
V
Site 53
S458
A
I
Q
H
S
S
V
S
T
S
N
G
V
S
S
Site 54
T459
I
Q
H
S
S
V
S
T
S
N
G
V
S
S
T
Site 55
S460
Q
H
S
S
V
S
T
S
N
G
V
S
S
T
S
Site 56
S464
V
S
T
S
N
G
V
S
S
T
S
K
A
E
A
Site 57
S465
S
T
S
N
G
V
S
S
T
S
K
A
E
A
V
Site 58
S484
L
T
Q
M
A
D
Q
S
T
E
P
A
L
S
Q
Site 59
S490
Q
S
T
E
P
A
L
S
Q
I
V
M
A
P
S
Site 60
S497
S
Q
I
V
M
A
P
S
S
Q
S
Q
P
S
G
Site 61
S498
Q
I
V
M
A
P
S
S
Q
S
Q
P
S
G
S
Site 62
S500
V
M
A
P
S
S
Q
S
Q
P
S
G
S
_
_
Site 63
S503
P
S
S
Q
S
Q
P
S
G
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation