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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JUP
Full Name:
Junction plakoglobin
Alias:
Catenin, gamma; CTNNG; Desmoplakin III; DP3; DPIII; Gamma-catenin; PDGB; PKGB; PLAK; Plakoglobin
Type:
Cytoskeletal protein
Mass (Da):
81745
Number AA:
745
UniProt ID:
P14923
International Prot ID:
IPI00554711
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030057
GO:0019898
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0008092
GO:0019903
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
K
V
T
E
W
Q
Q
T
Y
T
Y
D
S
G
I
Site 2
Y20
V
T
E
W
Q
Q
T
Y
T
Y
D
S
G
I
H
Site 3
T21
T
E
W
Q
Q
T
Y
T
Y
D
S
G
I
H
S
Site 4
Y22
E
W
Q
Q
T
Y
T
Y
D
S
G
I
H
S
G
Site 5
S24
Q
Q
T
Y
T
Y
D
S
G
I
H
S
G
A
N
Site 6
S28
T
Y
D
S
G
I
H
S
G
A
N
T
C
V
P
Site 7
T32
G
I
H
S
G
A
N
T
C
V
P
S
V
S
S
Site 8
S36
G
A
N
T
C
V
P
S
V
S
S
K
G
I
M
Site 9
Y53
D
E
A
C
G
R
Q
Y
T
L
K
K
T
T
T
Site 10
T54
E
A
C
G
R
Q
Y
T
L
K
K
T
T
T
Y
Site 11
T58
R
Q
Y
T
L
K
K
T
T
T
Y
T
Q
G
V
Site 12
T59
Q
Y
T
L
K
K
T
T
T
Y
T
Q
G
V
P
Site 13
T60
Y
T
L
K
K
T
T
T
Y
T
Q
G
V
P
P
Site 14
Y61
T
L
K
K
T
T
T
Y
T
Q
G
V
P
P
S
Site 15
T62
L
K
K
T
T
T
Y
T
Q
G
V
P
P
S
Q
Site 16
S68
Y
T
Q
G
V
P
P
S
Q
G
D
L
E
Y
Q
Site 17
Y74
P
S
Q
G
D
L
E
Y
Q
M
S
T
T
A
R
Site 18
S77
G
D
L
E
Y
Q
M
S
T
T
A
R
A
K
R
Site 19
S94
E
A
M
C
P
G
V
S
G
E
D
S
S
L
L
Site 20
S98
P
G
V
S
G
E
D
S
S
L
L
L
A
T
Q
Site 21
T111
T
Q
V
E
G
Q
A
T
N
L
Q
R
L
A
E
Site 22
S120
L
Q
R
L
A
E
P
S
Q
L
L
K
S
A
I
Site 23
Y133
A
I
V
H
L
I
N
Y
Q
D
D
A
E
L
A
Site 24
T141
Q
D
D
A
E
L
A
T
R
A
L
P
E
L
T
Site 25
S175
Q
L
S
K
K
E
A
S
R
R
A
L
M
G
S
Site 26
S182
S
R
R
A
L
M
G
S
P
Q
L
V
A
A
V
Site 27
T196
V
V
R
T
M
Q
N
T
S
D
L
D
T
A
R
Site 28
T201
Q
N
T
S
D
L
D
T
A
R
C
T
T
S
I
Site 29
T205
D
L
D
T
A
R
C
T
T
S
I
L
H
N
L
Site 30
T206
L
D
T
A
R
C
T
T
S
I
L
H
N
L
S
Site 31
S207
D
T
A
R
C
T
T
S
I
L
H
N
L
S
H
Site 32
S213
T
S
I
L
H
N
L
S
H
H
R
E
G
L
L
Site 33
Y297
D
C
L
Q
L
L
A
Y
G
N
Q
E
S
K
L
Site 34
Y322
L
V
Q
I
M
R
N
Y
S
Y
E
K
L
L
W
Site 35
T330
S
Y
E
K
L
L
W
T
T
S
R
V
L
K
V
Site 36
S339
S
R
V
L
K
V
L
S
V
C
P
S
N
K
P
Site 37
S363
A
L
G
K
H
L
T
S
N
S
P
R
L
V
Q
Site 38
S365
G
K
H
L
T
S
N
S
P
R
L
V
Q
N
C
Site 39
S380
L
W
T
L
R
N
L
S
D
V
A
T
K
Q
E
Site 40
T384
R
N
L
S
D
V
A
T
K
Q
E
G
L
E
S
Site 41
S391
T
K
Q
E
G
L
E
S
V
L
K
I
L
V
N
Site 42
S416
T
C
A
T
G
T
L
S
N
L
T
C
N
N
S
Site 43
T419
T
G
T
L
S
N
L
T
C
N
N
S
K
N
K
Site 44
S423
S
N
L
T
C
N
N
S
K
N
K
T
L
V
T
Site 45
T427
C
N
N
S
K
N
K
T
L
V
T
Q
N
S
G
Site 46
T430
S
K
N
K
T
L
V
T
Q
N
S
G
V
E
A
Site 47
T452
A
G
D
K
D
D
I
T
E
P
A
V
C
A
L
Site 48
T463
V
C
A
L
R
H
L
T
S
R
H
P
E
A
E
Site 49
S464
C
A
L
R
H
L
T
S
R
H
P
E
A
E
M
Site 50
S475
E
A
E
M
A
Q
N
S
V
R
L
N
Y
G
I
Site 51
Y480
Q
N
S
V
R
L
N
Y
G
I
P
A
I
V
K
Site 52
Y550
A
A
G
T
Q
Q
P
Y
T
D
G
V
R
M
E
Site 53
T551
A
G
T
Q
Q
P
Y
T
D
G
V
R
M
E
E
Site 54
T564
E
E
I
V
E
G
C
T
G
A
L
H
I
L
A
Site 55
S596
F
V
Q
L
L
Y
S
S
V
E
N
I
Q
R
V
Site 56
S636
P
L
M
E
L
L
H
S
R
N
E
G
T
A
T
Site 57
Y644
R
N
E
G
T
A
T
Y
A
A
A
V
L
F
R
Site 58
S653
A
A
V
L
F
R
I
S
E
D
K
N
P
D
Y
Site 59
Y660
S
E
D
K
N
P
D
Y
R
K
R
V
S
V
E
Site 60
S665
P
D
Y
R
K
R
V
S
V
E
L
T
N
S
L
Site 61
T669
K
R
V
S
V
E
L
T
N
S
L
F
K
H
D
Site 62
S671
V
S
V
E
L
T
N
S
L
F
K
H
D
P
A
Site 63
S685
A
A
W
E
A
A
Q
S
M
I
P
I
N
E
P
Site 64
T700
Y
G
D
D
M
D
A
T
Y
R
P
M
Y
S
S
Site 65
Y701
G
D
D
M
D
A
T
Y
R
P
M
Y
S
S
D
Site 66
Y705
D
A
T
Y
R
P
M
Y
S
S
D
V
P
L
D
Site 67
S707
T
Y
R
P
M
Y
S
S
D
V
P
L
D
P
L
Site 68
Y724
H
M
D
M
D
G
D
Y
P
I
D
T
Y
S
D
Site 69
T728
D
G
D
Y
P
I
D
T
Y
S
D
G
L
R
P
Site 70
Y729
G
D
Y
P
I
D
T
Y
S
D
G
L
R
P
P
Site 71
S730
D
Y
P
I
D
T
Y
S
D
G
L
R
P
P
Y
Site 72
Y737
S
D
G
L
R
P
P
Y
P
T
A
D
H
M
L
Site 73
T739
G
L
R
P
P
Y
P
T
A
D
H
M
L
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation