PhosphoNET

           
Protein Info 
   
Short Name:  IL2RB
Full Name:  Interleukin-2 receptor subunit beta
Alias:  CD122; CD122 antigen; High affinity IL-2 receptor beta subunit; IL-2 receptor; IL-2R beta; Interleukin 2 receptor, beta; Interleukin-2 receptor beta chain precursor; P70-75
Type:  Receptor, cytokine
Mass (Da):  61117
Number AA:  551
UniProt ID:  P14784
International Prot ID:  IPI00027510
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0009897  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0004911     PhosphoSite+ KinaseNET
Biological Process:  GO:0019221  GO:0044419  GO:0045885 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T105LTTVDIVTLRVLCRE
Site 2T270LLINCRNTGPWLKKV
Site 3T282KKVLKCNTPDPSKFF
Site 4S286KCNTPDPSKFFSQLS
Site 5S290PDPSKFFSQLSSEHG
Site 6S293SKFFSQLSSEHGGDV
Site 7S294KFFSQLSSEHGGDVQ
Site 8S305GDVQKWLSSPFPSSS
Site 9S306DVQKWLSSPFPSSSF
Site 10S310WLSSPFPSSSFSPGG
Site 11S311LSSPFPSSSFSPGGL
Site 12S312SSPFPSSSFSPGGLA
Site 13S314PFPSSSFSPGGLAPE
Site 14S348DKVPEPASLSSNHSL
Site 15S350VPEPASLSSNHSLTS
Site 16S351PEPASLSSNHSLTSC
Site 17S354ASLSSNHSLTSCFTN
Site 18T356LSSNHSLTSCFTNQG
Site 19S357SSNHSLTSCFTNQGY
Site 20Y364SCFTNQGYFFFHLPD
Site 21Y381EIEACQVYFTYDPYS
Site 22T383EACQVYFTYDPYSEE
Site 23Y384ACQVYFTYDPYSEED
Site 24Y387VYFTYDPYSEEDPDE
Site 25S388YFTYDPYSEEDPDEG
Site 26S404AGAPTGSSPQPLQPL
Site 27S412PQPLQPLSGEDDAYC
Site 28Y418LSGEDDAYCTFPSRD
Site 29T420GEDDAYCTFPSRDDL
Site 30S439PSLLGGPSPPSTAPG
Site 31S442LGGPSPPSTAPGGSG
Site 32T443GGPSPPSTAPGGSGA
Site 33S458GEERMPPSLQERVPR
Site 34T476PQPLGPPTPGVPDLV
Site 35S510AGPREGVSFPWSRPP
Site 36S514EGVSFPWSRPPGQGE
Site 37T533NARLPLNTDAYLSLQ
Site 38Y536LPLNTDAYLSLQELQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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