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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GYS1
Full Name:
Glycogen [starch] synthase, muscle
Alias:
EC 2.4.1.11; Glycogen synthase 1 (muscle); Glycogen synthase, muscle; GSY; GYS
Type:
EC 2.4.1.11; Carbohydrate Metabolism - starch and sucrose; Transferase
Mass (Da):
83786
Number AA:
737
UniProt ID:
P13807
International Prot ID:
IPI00303868
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0004373
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0005978
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
P
L
N
R
T
L
S
M
S
S
L
P
Site 2
S8
M
P
L
N
R
T
L
S
M
S
S
L
P
G
L
Site 3
S10
L
N
R
T
L
S
M
S
S
L
P
G
L
E
D
Site 4
S11
N
R
T
L
S
M
S
S
L
P
G
L
E
D
W
Site 5
Y44
A
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
Site 6
T45
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
K
Site 7
Y62
G
D
E
W
G
D
N
Y
F
L
V
G
P
Y
T
Site 8
T69
Y
F
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Site 9
T90
P
T
P
A
L
K
R
T
L
D
S
M
N
S
K
Site 10
S93
A
L
K
R
T
L
D
S
M
N
S
K
G
C
K
Site 11
S96
R
T
L
D
S
M
N
S
K
G
C
K
V
Y
F
Site 12
Y102
N
S
K
G
C
K
V
Y
F
G
R
W
L
I
E
Site 13
Y144
C
N
I
G
V
P
W
Y
D
R
E
A
N
D
A
Site 14
Y221
C
A
G
A
V
D
F
Y
N
N
L
E
N
F
N
Site 15
Y239
E
A
G
E
R
Q
I
Y
H
R
Y
C
M
E
R
Site 16
T278
K
R
K
P
D
I
V
T
P
N
G
L
N
V
K
Site 17
Y313
E
F
V
R
G
H
F
Y
G
H
L
D
F
N
L
Site 18
Y351
E
A
L
A
R
L
N
Y
L
L
R
V
N
G
S
Site 19
T392
V
R
K
Q
L
W
D
T
A
N
T
V
K
E
K
Site 20
Y405
E
K
F
G
R
K
L
Y
E
S
L
L
V
G
S
Site 21
S412
Y
E
S
L
L
V
G
S
L
P
D
M
N
K
M
Site 22
T435
M
K
R
A
I
F
A
T
Q
R
Q
S
F
P
P
Site 23
S439
I
F
A
T
Q
R
Q
S
F
P
P
V
C
T
H
Site 24
S452
T
H
N
M
L
D
D
S
S
D
P
I
L
T
T
Site 25
S453
H
N
M
L
D
D
S
S
D
P
I
L
T
T
I
Site 26
T458
D
S
S
D
P
I
L
T
T
I
R
R
I
G
L
Site 27
S468
R
R
I
G
L
F
N
S
S
A
D
R
V
K
V
Site 28
S486
P
E
F
L
S
S
T
S
P
L
L
P
V
D
Y
Site 29
Y493
S
P
L
L
P
V
D
Y
E
E
F
V
R
G
C
Site 30
Y508
H
L
G
V
F
P
S
Y
Y
E
P
W
G
Y
T
Site 31
Y509
L
G
V
F
P
S
Y
Y
E
P
W
G
Y
T
P
Site 32
Y514
S
Y
Y
E
P
W
G
Y
T
P
A
E
C
T
V
Site 33
S559
I
L
D
R
R
F
R
S
L
D
D
S
C
S
Q
Site 34
S563
R
F
R
S
L
D
D
S
C
S
Q
L
T
S
F
Site 35
S565
R
S
L
D
D
S
C
S
Q
L
T
S
F
L
Y
Site 36
S569
D
S
C
S
Q
L
T
S
F
L
Y
S
F
C
Q
Site 37
Y572
S
Q
L
T
S
F
L
Y
S
F
C
Q
Q
S
R
Site 38
S573
Q
L
T
S
F
L
Y
S
F
C
Q
Q
S
R
R
Site 39
T589
R
I
I
Q
R
N
R
T
E
R
L
S
D
L
L
Site 40
S593
R
N
R
T
E
R
L
S
D
L
L
D
W
K
Y
Site 41
Y600
S
D
L
L
D
W
K
Y
L
G
R
Y
Y
M
S
Site 42
Y604
D
W
K
Y
L
G
R
Y
Y
M
S
A
R
H
M
Site 43
Y605
W
K
Y
L
G
R
Y
Y
M
S
A
R
H
M
A
Site 44
S614
S
A
R
H
M
A
L
S
K
A
F
P
E
H
F
Site 45
T622
K
A
F
P
E
H
F
T
Y
E
P
N
E
A
D
Site 46
Y623
A
F
P
E
H
F
T
Y
E
P
N
E
A
D
A
Site 47
Y634
E
A
D
A
A
Q
G
Y
R
Y
P
R
P
A
S
Site 48
Y636
D
A
A
Q
G
Y
R
Y
P
R
P
A
S
V
P
Site 49
S641
Y
R
Y
P
R
P
A
S
V
P
P
S
P
S
L
Site 50
S645
R
P
A
S
V
P
P
S
P
S
L
S
R
H
S
Site 51
S647
A
S
V
P
P
S
P
S
L
S
R
H
S
S
P
Site 52
S649
V
P
P
S
P
S
L
S
R
H
S
S
P
H
Q
Site 53
S652
S
P
S
L
S
R
H
S
S
P
H
Q
S
E
D
Site 54
S653
P
S
L
S
R
H
S
S
P
H
Q
S
E
D
E
Site 55
S657
R
H
S
S
P
H
Q
S
E
D
E
E
D
P
R
Site 56
Y675
L
E
E
D
G
E
R
Y
D
E
D
E
E
A
A
Site 57
S698
P
E
W
P
R
R
A
S
C
T
S
S
T
S
G
Site 58
T700
W
P
R
R
A
S
C
T
S
S
T
S
G
S
K
Site 59
S701
P
R
R
A
S
C
T
S
S
T
S
G
S
K
R
Site 60
S702
R
R
A
S
C
T
S
S
T
S
G
S
K
R
N
Site 61
S704
A
S
C
T
S
S
T
S
G
S
K
R
N
S
V
Site 62
S706
C
T
S
S
T
S
G
S
K
R
N
S
V
D
T
Site 63
S710
T
S
G
S
K
R
N
S
V
D
T
A
T
S
S
Site 64
T713
S
K
R
N
S
V
D
T
A
T
S
S
S
L
S
Site 65
T715
R
N
S
V
D
T
A
T
S
S
S
L
S
T
P
Site 66
S716
N
S
V
D
T
A
T
S
S
S
L
S
T
P
S
Site 67
S717
S
V
D
T
A
T
S
S
S
L
S
T
P
S
E
Site 68
S718
V
D
T
A
T
S
S
S
L
S
T
P
S
E
P
Site 69
S720
T
A
T
S
S
S
L
S
T
P
S
E
P
L
S
Site 70
T721
A
T
S
S
S
L
S
T
P
S
E
P
L
S
P
Site 71
S723
S
S
S
L
S
T
P
S
E
P
L
S
P
T
S
Site 72
S727
S
T
P
S
E
P
L
S
P
T
S
S
L
G
E
Site 73
T729
P
S
E
P
L
S
P
T
S
S
L
G
E
E
R
Site 74
S730
S
E
P
L
S
P
T
S
S
L
G
E
E
R
N
Site 75
S731
E
P
L
S
P
T
S
S
L
G
E
E
R
N
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation