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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH1
Full Name:
Cadherin-1
Alias:
CADH1; Cadherin 1, type 1, E-cadherin (epithelial); Cadherin 1, type 1, E-cadherin (epithelial) (ECAD); Cadherin-1; CAM 120,80; CAM 120/80; CD324; CDHE; E-cadherin; Epithelial-cadherin; UVO; Uvomorulin
Type:
Adhesion protein
Mass (Da):
97456
Number AA:
882
UniProt ID:
P12830
International Prot ID:
IPI00025861
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0015629
GO:0016342
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0050839
GO:0016563
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
GO:0042993
GO:0043281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
H
P
G
F
D
A
E
S
Y
T
F
T
V
P
R
Site 2
Y37
P
G
F
D
A
E
S
Y
T
F
T
V
P
R
R
Site 3
T38
G
F
D
A
E
S
Y
T
F
T
V
P
R
R
H
Site 4
T40
D
A
E
S
Y
T
F
T
V
P
R
R
H
L
E
Site 5
T61
R
V
N
F
E
D
C
T
G
R
Q
R
T
A
Y
Site 6
T66
D
C
T
G
R
Q
R
T
A
Y
F
S
L
D
T
Site 7
Y68
T
G
R
Q
R
T
A
Y
F
S
L
D
T
R
F
Site 8
S70
R
Q
R
T
A
Y
F
S
L
D
T
R
F
K
V
Site 9
T79
D
T
R
F
K
V
G
T
D
G
V
I
T
V
K
Site 10
Y101
P
Q
I
H
F
L
V
Y
A
W
D
S
T
Y
R
Site 11
T106
L
V
Y
A
W
D
S
T
Y
R
K
F
S
T
K
Site 12
Y107
V
Y
A
W
D
S
T
Y
R
K
F
S
T
K
V
Site 13
S111
D
S
T
Y
R
K
F
S
T
K
V
T
L
N
T
Site 14
T115
R
K
F
S
T
K
V
T
L
N
T
V
G
H
H
Site 15
T118
S
T
K
V
T
L
N
T
V
G
H
H
H
R
P
Site 16
S131
R
P
P
P
H
Q
A
S
V
S
G
I
Q
A
E
Site 17
T141
G
I
Q
A
E
L
L
T
F
P
N
S
S
P
G
Site 18
S145
E
L
L
T
F
P
N
S
S
P
G
L
R
R
Q
Site 19
S146
L
L
T
F
P
N
S
S
P
G
L
R
R
Q
K
Site 20
T211
V
F
I
I
E
R
E
T
G
W
L
K
V
T
E
Site 21
T330
T
G
V
I
S
V
V
T
T
G
L
D
R
E
S
Site 22
T394
N
E
A
N
V
V
I
T
T
L
K
V
T
D
A
Site 23
T395
E
A
N
V
V
I
T
T
L
K
V
T
D
A
D
Site 24
T576
D
N
G
S
P
V
A
T
G
T
G
T
L
L
L
Site 25
T748
L
L
P
P
E
D
D
T
R
D
N
V
Y
Y
Y
Site 26
Y753
D
D
T
R
D
N
V
Y
Y
Y
D
E
E
G
G
Site 27
Y754
D
T
R
D
N
V
Y
Y
Y
D
E
E
G
G
G
Site 28
Y755
T
R
D
N
V
Y
Y
Y
D
E
E
G
G
G
E
Site 29
S770
E
D
Q
D
F
D
L
S
Q
L
H
R
G
L
D
Site 30
T790
T
R
N
D
V
A
P
T
L
M
S
V
P
R
Y
Site 31
S793
D
V
A
P
T
L
M
S
V
P
R
Y
L
P
R
Site 32
Y797
T
L
M
S
V
P
R
Y
L
P
R
P
A
N
P
Site 33
T820
E
N
L
K
A
A
D
T
D
P
T
A
P
P
Y
Site 34
T823
K
A
A
D
T
D
P
T
A
P
P
Y
D
S
L
Site 35
Y827
T
D
P
T
A
P
P
Y
D
S
L
L
V
F
D
Site 36
S829
P
T
A
P
P
Y
D
S
L
L
V
F
D
Y
E
Site 37
Y835
D
S
L
L
V
F
D
Y
E
G
S
G
S
E
A
Site 38
S838
L
V
F
D
Y
E
G
S
G
S
E
A
A
S
L
Site 39
S840
F
D
Y
E
G
S
G
S
E
A
A
S
L
S
S
Site 40
S844
G
S
G
S
E
A
A
S
L
S
S
L
N
S
S
Site 41
S846
G
S
E
A
A
S
L
S
S
L
N
S
S
E
S
Site 42
S847
S
E
A
A
S
L
S
S
L
N
S
S
E
S
D
Site 43
S850
A
S
L
S
S
L
N
S
S
E
S
D
K
D
Q
Site 44
S851
S
L
S
S
L
N
S
S
E
S
D
K
D
Q
D
Site 45
S853
S
S
L
N
S
S
E
S
D
K
D
Q
D
Y
D
Site 46
Y859
E
S
D
K
D
Q
D
Y
D
Y
L
N
E
W
G
Site 47
Y861
D
K
D
Q
D
Y
D
Y
L
N
E
W
G
N
R
Site 48
Y876
F
K
K
L
A
D
M
Y
G
G
G
E
D
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation