KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PCNA
Full Name:
Proliferating cell nuclear antigen
Alias:
Cyclin
Type:
Cell cycle regulation
Mass (Da):
28769
Number AA:
261
UniProt ID:
P12004
International Prot ID:
IPI00021700
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005663
GO:0043626
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0030337
GO:0032405
GO:0032139
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0008283
GO:0006298
Phosida
TranscriptoNet
STRING
Kinexus Products
DNA polymerase delta auxiliary protein pan-specific antibody AB-NN087-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN087-2
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
E
A
C
W
D
I
S
S
S
G
V
N
L
Q
S
Site 2
S33
A
C
W
D
I
S
S
S
G
V
N
L
Q
S
M
Site 3
S39
S
S
G
V
N
L
Q
S
M
D
S
S
H
V
S
Site 4
S42
V
N
L
Q
S
M
D
S
S
H
V
S
L
V
Q
Site 5
S43
N
L
Q
S
M
D
S
S
H
V
S
L
V
Q
L
Site 6
S46
S
M
D
S
S
H
V
S
L
V
Q
L
T
L
R
Site 7
T51
H
V
S
L
V
Q
L
T
L
R
S
E
G
F
D
Site 8
T59
L
R
S
E
G
F
D
T
Y
R
C
D
R
N
L
Site 9
Y60
R
S
E
G
F
D
T
Y
R
C
D
R
N
L
A
Site 10
T89
A
G
N
E
D
I
I
T
L
R
A
E
D
N
A
Site 11
T98
R
A
E
D
N
A
D
T
L
A
L
V
F
E
A
Site 12
Y114
N
Q
E
K
V
S
D
Y
E
M
K
L
M
D
L
Site 13
Y133
L
G
I
P
E
Q
E
Y
S
C
V
V
K
M
P
Site 14
S134
G
I
P
E
Q
E
Y
S
C
V
V
K
M
P
S
Site 15
S170
A
K
D
G
V
K
F
S
A
S
G
E
L
G
N
Site 16
S172
D
G
V
K
F
S
A
S
G
E
L
G
N
G
N
Site 17
S183
G
N
G
N
I
K
L
S
Q
T
S
N
V
D
K
Site 18
T196
D
K
E
E
E
A
V
T
I
E
M
N
E
P
V
Site 19
T206
M
N
E
P
V
Q
L
T
F
A
L
R
Y
L
N
Site 20
Y211
Q
L
T
F
A
L
R
Y
L
N
F
F
T
K
A
Site 21
Y239
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Site 22
Y250
D
M
G
H
L
K
Y
Y
L
A
P
K
I
E
D
Site 23
S261
K
I
E
D
E
E
G
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation