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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PYGB
Full Name:
Glycogen phosphorylase, brain form
Alias:
Brain; EC 2.4.1.1; Phosphorylase, glycogen; PHS3
Type:
EC 2.4.1.1; Phosphorylase; Transferase; Kinase (non-protein); Carbohydrate Metabolism - starch and sucrose
Mass (Da):
96696
Number AA:
843
UniProt ID:
P11216
International Prot ID:
IPI00004358
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0008184
GO:0030170
PhosphoSite+
KinaseNET
Biological Process:
GO:0005980
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
A
K
P
L
T
D
S
E
K
R
K
Q
Site 2
S8
M
A
K
P
L
T
D
S
E
K
R
K
Q
I
S
Site 3
S15
S
E
K
R
K
Q
I
S
V
R
G
L
A
G
L
Site 4
S31
D
V
A
E
V
R
K
S
F
N
R
H
L
H
F
Site 5
T39
F
N
R
H
L
H
F
T
L
V
K
D
R
N
V
Site 6
T48
V
K
D
R
N
V
A
T
P
R
D
Y
F
F
A
Site 7
Y52
N
V
A
T
P
R
D
Y
F
F
A
L
A
H
T
Site 8
Y75
W
I
R
T
Q
Q
H
Y
Y
E
R
D
P
K
R
Site 9
Y76
I
R
T
Q
Q
H
Y
Y
E
R
D
P
K
R
I
Site 10
Y84
E
R
D
P
K
R
I
Y
Y
L
S
L
E
F
Y
Site 11
Y85
R
D
P
K
R
I
Y
Y
L
S
L
E
F
Y
M
Site 12
S87
P
K
R
I
Y
Y
L
S
L
E
F
Y
M
G
R
Site 13
Y91
Y
Y
L
S
L
E
F
Y
M
G
R
T
L
Q
N
Site 14
T99
M
G
R
T
L
Q
N
T
M
V
N
L
G
L
Q
Site 15
Y156
A
T
L
G
L
A
A
Y
G
Y
G
I
R
Y
E
Site 16
Y162
A
Y
G
Y
G
I
R
Y
E
F
G
I
F
N
Q
Site 17
Y186
E
A
D
D
W
L
R
Y
G
N
P
W
E
K
A
Site 18
Y197
W
E
K
A
R
P
E
Y
M
L
P
V
H
F
Y
Site 19
Y204
Y
M
L
P
V
H
F
Y
G
R
V
E
H
T
P
Site 20
T210
F
Y
G
R
V
E
H
T
P
D
G
V
K
W
L
Site 21
Y227
Q
V
V
L
A
M
P
Y
D
T
P
V
P
G
Y
Site 22
T229
V
L
A
M
P
Y
D
T
P
V
P
G
Y
K
N
Site 23
T241
Y
K
N
N
T
V
N
T
M
R
L
W
S
A
K
Site 24
Y263
Q
D
F
N
V
G
D
Y
I
E
A
V
L
D
R
Site 25
S277
R
N
L
A
E
N
I
S
R
V
L
Y
P
N
D
Site 26
Y281
E
N
I
S
R
V
L
Y
P
N
D
N
F
F
E
Site 27
S314
D
I
I
R
R
F
K
S
S
K
F
G
C
R
D
Site 28
S315
I
I
R
R
F
K
S
S
K
F
G
C
R
D
P
Site 29
T325
G
C
R
D
P
V
R
T
C
F
E
T
F
P
D
Site 30
S346
N
D
T
H
P
A
L
S
I
P
E
L
M
R
I
Site 31
T379
T
C
A
Y
T
N
H
T
V
L
P
E
A
L
E
Site 32
Y405
P
R
H
L
E
I
I
Y
A
I
N
Q
R
H
L
Site 33
S430
V
D
R
L
R
R
M
S
V
I
E
E
G
D
C
Site 34
S461
N
G
V
A
R
I
H
S
E
I
V
K
Q
S
V
Site 35
Y473
Q
S
V
F
K
D
F
Y
E
L
E
P
E
K
F
Site 36
T484
P
E
K
F
Q
N
K
T
N
G
I
T
P
R
R
Site 37
T488
Q
N
K
T
N
G
I
T
P
R
R
W
L
L
L
Site 38
T514
K
I
G
E
E
F
L
T
D
L
S
Q
L
K
K
Site 39
S517
E
E
F
L
T
D
L
S
Q
L
K
K
L
L
P
Site 40
Y554
S
A
F
L
E
K
E
Y
K
V
K
I
N
P
S
Site 41
S562
K
V
K
I
N
P
S
S
M
F
D
V
H
V
K
Site 42
Y574
H
V
K
R
I
H
E
Y
K
R
Q
L
L
N
C
Site 43
Y588
C
L
H
V
V
T
L
Y
N
R
I
K
R
D
P
Site 44
S668
A
D
L
S
Q
Q
I
S
T
A
G
T
E
A
S
Site 45
T672
Q
Q
I
S
T
A
G
T
E
A
S
G
T
G
N
Site 46
S675
S
T
A
G
T
E
A
S
G
T
G
N
M
K
F
Site 47
T677
A
G
T
E
A
S
G
T
G
N
M
K
F
M
L
Site 48
Y727
E
A
L
D
R
K
G
Y
N
A
R
E
Y
Y
D
Site 49
Y732
K
G
Y
N
A
R
E
Y
Y
D
H
L
P
E
L
Site 50
Y733
G
Y
N
A
R
E
Y
Y
D
H
L
P
E
L
K
Site 51
S747
K
Q
A
V
D
Q
I
S
S
G
F
F
S
P
K
Site 52
S748
Q
A
V
D
Q
I
S
S
G
F
F
S
P
K
E
Site 53
S752
Q
I
S
S
G
F
F
S
P
K
E
P
D
C
F
Site 54
Y778
R
F
K
V
F
A
D
Y
E
A
Y
M
Q
C
Q
Site 55
Y792
Q
A
Q
V
D
Q
L
Y
R
N
P
K
E
W
T
Site 56
S809
V
I
R
N
I
A
C
S
G
K
F
S
S
D
R
Site 57
S813
I
A
C
S
G
K
F
S
S
D
R
T
I
T
E
Site 58
S814
A
C
S
G
K
F
S
S
D
R
T
I
T
E
Y
Site 59
T817
G
K
F
S
S
D
R
T
I
T
E
Y
A
R
E
Site 60
T819
F
S
S
D
R
T
I
T
E
Y
A
R
E
I
W
Site 61
Y821
S
D
R
T
I
T
E
Y
A
R
E
I
W
G
V
Site 62
S831
E
I
W
G
V
E
P
S
D
L
Q
I
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation