PhosphoNET

           
Protein Info 
   
Short Name:  CD3-epsilon
Full Name:  T-cell surface glycoprotein CD3 epsilon chain
Alias:  T-cell surface antigen T3/Leu-4 epsilon chain
Type:  Receptor
Mass (Da):  23147
Number AA:  207
UniProt ID:  P07766
International Prot ID:  IPI00012923
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0009897  GO:0005887  GO:0042101 Uniprot OncoNet
Molecular Function:  GO:0017124  GO:0042608  GO:0046982 PhosphoSite+ KinaseNET
Biological Process:  GO:0007186  GO:0007172  GO:0042981 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S77EDDKNIGSDEDHLSL
Site 2Y149GGLLLLVYYWSKNRK
Site 3Y150GLLLLVYYWSKNRKA
Site 4S152LLLVYYWSKNRKAKA
Site 5Y188PPVPNPDYEPIRKGQ
Site 6Y199RKGQRDLYSGLNQRR
Site 7S200KGQRDLYSGLNQRRI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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