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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LDH-B
Full Name:
L-lactate dehydrogenase B chain
Alias:
EC 1.1.1.27; Lactate dehydrogenase B; LDH heart subunit; LDHB; LDH-H
Type:
Oxidoreductase; Carbohydrate Metabolism - propanoate; EC 1.1.1.27; Amino Acid Metabolism - cysteine and methionine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate
Mass (Da):
36638
Number AA:
333
UniProt ID:
P07195
International Prot ID:
IPI00219217
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004459
PhosphoSite+
KinaseNET
Biological Process:
GO:0019642
GO:0055114
GO:0006090
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
P
V
A
E
E
E
A
T
V
P
N
N
K
I
T
Site 2
S39
V
G
M
A
C
A
I
S
I
L
G
K
S
L
A
Site 3
S44
A
I
S
I
L
G
K
S
L
A
D
E
L
A
L
Site 4
S70
M
M
D
L
Q
H
G
S
L
F
L
Q
T
P
K
Site 5
T75
H
G
S
L
F
L
Q
T
P
K
I
V
A
D
K
Site 6
Y84
K
I
V
A
D
K
D
Y
S
V
T
A
N
S
K
Site 7
S85
I
V
A
D
K
D
Y
S
V
T
A
N
S
K
I
Site 8
T96
N
S
K
I
V
V
V
T
A
G
V
R
Q
Q
E
Site 9
S106
V
R
Q
Q
E
G
E
S
R
L
N
L
V
Q
R
Site 10
Y128
I
I
P
Q
I
V
K
Y
S
P
D
C
I
I
I
Site 11
Y146
N
P
V
D
I
L
T
Y
V
T
W
K
L
S
G
Site 12
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Site 13
S162
P
K
H
R
V
I
G
S
G
C
N
L
D
S
A
Site 14
S168
G
S
G
C
N
L
D
S
A
R
F
R
Y
L
M
Site 15
Y173
L
D
S
A
R
F
R
Y
L
M
A
E
K
L
G
Site 16
S238
V
H
K
M
V
V
E
S
A
Y
E
V
I
K
L
Site 17
Y240
K
M
V
V
E
S
A
Y
E
V
I
K
L
K
G
Site 18
Y248
E
V
I
K
L
K
G
Y
T
N
W
A
I
G
L
Site 19
T249
V
I
K
L
K
G
Y
T
N
W
A
I
G
L
S
Site 20
S263
S
V
A
D
L
I
E
S
M
L
K
N
L
S
R
Site 21
S269
E
S
M
L
K
N
L
S
R
I
H
P
V
S
T
Site 22
T276
S
R
I
H
P
V
S
T
M
V
K
G
M
Y
G
Site 23
S291
I
E
N
E
V
F
L
S
L
P
C
I
L
N
A
Site 24
S303
L
N
A
R
G
L
T
S
V
I
N
Q
K
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation