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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPN2
Full Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Alias:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa; RIB2; RIBIIR; Ribophorin II; RPNII; RPN-II; SWP1
Type:
EC 2.4.1.119; Transferase; Glycan Metabolism - N-glycan biosynthesis
Mass (Da):
69284
Number AA:
631
UniProt ID:
P04844
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0008250
Uniprot
OncoNet
Molecular Function:
GO:0004579
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0018279
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
I
A
S
T
W
A
L
T
P
T
H
Y
L
T
K
Site 2
T26
S
T
W
A
L
T
P
T
H
Y
L
T
K
H
D
Site 3
S40
D
V
E
R
L
K
A
S
L
D
R
P
F
T
N
Site 4
T46
A
S
L
D
R
P
F
T
N
L
E
S
A
F
Y
Site 5
S50
R
P
F
T
N
L
E
S
A
F
Y
S
I
V
G
Site 6
T73
P
D
A
K
K
A
C
T
Y
I
R
S
N
L
D
Site 7
Y74
D
A
K
K
A
C
T
Y
I
R
S
N
L
D
P
Site 8
S77
K
A
C
T
Y
I
R
S
N
L
D
P
S
N
V
Site 9
S82
I
R
S
N
L
D
P
S
N
V
D
S
L
F
Y
Site 10
S86
L
D
P
S
N
V
D
S
L
F
Y
A
A
Q
A
Site 11
S103
A
L
S
G
C
E
I
S
I
S
N
E
T
K
D
Site 12
S105
S
G
C
E
I
S
I
S
N
E
T
K
D
L
L
Site 13
S121
A
A
V
S
E
D
S
S
V
T
Q
I
Y
H
A
Site 14
T157
A
R
L
S
K
E
E
T
V
L
A
T
V
Q
A
Site 15
S172
L
Q
T
A
S
H
L
S
Q
Q
A
D
L
R
S
Site 16
S179
S
Q
Q
A
D
L
R
S
I
V
E
E
I
E
D
Site 17
Y198
L
D
E
L
G
G
V
Y
L
Q
F
E
E
G
L
Site 18
Y216
A
L
F
V
A
A
T
Y
K
L
M
D
H
V
G
Site 19
S248
F
S
K
K
N
F
E
S
L
S
E
A
F
S
V
Site 20
S250
K
K
N
F
E
S
L
S
E
A
F
S
V
A
S
Site 21
S263
A
S
A
A
A
V
L
S
H
N
R
Y
H
V
P
Site 22
S280
V
V
P
E
G
S
A
S
D
T
H
E
Q
A
I
Site 23
T282
P
E
G
S
A
S
D
T
H
E
Q
A
I
L
R
Site 24
T301
N
V
L
S
Q
P
L
T
Q
A
T
V
K
L
E
Site 25
S312
V
K
L
E
H
A
K
S
V
A
S
R
A
T
V
Site 26
T318
K
S
V
A
S
R
A
T
V
L
Q
K
T
S
F
Site 27
Y346
V
K
F
S
S
G
Y
Y
D
F
L
V
E
V
E
Site 28
Y358
E
V
E
G
D
N
R
Y
I
A
N
T
V
E
L
Site 29
T362
D
N
R
Y
I
A
N
T
V
E
L
R
V
K
I
Site 30
S381
G
I
T
N
V
D
L
S
T
V
D
K
D
Q
S
Site 31
T382
I
T
N
V
D
L
S
T
V
D
K
D
Q
S
I
Site 32
S388
S
T
V
D
K
D
Q
S
I
A
P
K
T
T
R
Site 33
T393
D
Q
S
I
A
P
K
T
T
R
V
T
Y
P
A
Site 34
T397
A
P
K
T
T
R
V
T
Y
P
A
K
A
K
G
Site 35
Y398
P
K
T
T
R
V
T
Y
P
A
K
A
K
G
T
Site 36
T405
Y
P
A
K
A
K
G
T
F
I
A
D
S
H
Q
Site 37
T425
F
Q
L
V
D
V
N
T
G
A
E
L
T
P
H
Site 38
T430
V
N
T
G
A
E
L
T
P
H
Q
T
F
V
R
Site 39
T434
A
E
L
T
P
H
Q
T
F
V
R
L
H
N
Q
Site 40
T465
V
Y
K
F
E
L
D
T
S
E
R
K
I
E
F
Site 41
S466
Y
K
F
E
L
D
T
S
E
R
K
I
E
F
D
Site 42
S474
E
R
K
I
E
F
D
S
A
S
G
T
Y
T
L
Site 43
S476
K
I
E
F
D
S
A
S
G
T
Y
T
L
Y
L
Site 44
S512
F
P
E
E
E
A
P
S
T
V
L
S
Q
N
L
Site 45
T513
P
E
E
E
A
P
S
T
V
L
S
Q
N
L
F
Site 46
S516
E
A
P
S
T
V
L
S
Q
N
L
F
T
P
K
Site 47
T521
V
L
S
Q
N
L
F
T
P
K
Q
E
I
Q
H
Site 48
T539
E
P
E
K
R
P
P
T
V
V
S
N
T
F
T
Site 49
T546
T
V
V
S
N
T
F
T
A
L
I
L
S
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation