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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDOA
Full Name:
Fructose-bisphosphate aldolase A
Alias:
ALDA; ALD-A; ALDO-A; Aldolase A, fructose-bisphosphate; ALFA; Lung cancer antigen NY-LU-1; Muscle-type aldolase
Type:
Carbohydrate Metabolism - fructose and mannose; Lyase; Mitochondrial; EC 4.1.2.13; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - glycolysis and gluconeogenesis
Mass (Da):
39420
Number AA:
364
UniProt ID:
P04075
International Prot ID:
IPI00465439
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031674
GO:0015629
GO:0070062
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0070061
GO:0004332
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0007015
GO:0030388
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
_
P
Y
Q
Y
P
A
L
T
P
Site 2
Y5
_
_
_
_
P
Y
Q
Y
P
A
L
T
P
E
Q
Site 3
T9
P
Y
Q
Y
P
A
L
T
P
E
Q
K
K
E
L
Site 4
S17
P
E
Q
K
K
E
L
S
D
I
A
H
R
I
V
Site 5
S36
G
I
L
A
A
D
E
S
T
G
S
I
A
K
R
Site 6
T37
I
L
A
A
D
E
S
T
G
S
I
A
K
R
L
Site 7
S39
A
A
D
E
S
T
G
S
I
A
K
R
L
Q
S
Site 8
S46
S
I
A
K
R
L
Q
S
I
G
T
E
N
T
E
Site 9
T49
K
R
L
Q
S
I
G
T
E
N
T
E
E
N
R
Site 10
T52
Q
S
I
G
T
E
N
T
E
E
N
R
R
F
Y
Site 11
Y59
_
_
_
M
P
Y
Q
Y
P
A
L
T
P
E
Q
Site 12
T65
F
Y
R
Q
L
L
L
T
A
D
D
R
V
N
P
Site 13
Y85
I
L
F
H
E
T
L
Y
Q
K
A
D
D
G
R
Site 14
S132
T
Q
G
L
D
G
L
S
E
R
C
A
Q
Y
K
Site 15
Y138
L
S
E
R
C
A
Q
Y
K
K
D
G
A
D
F
Site 16
S160
K
I
G
E
H
T
P
S
A
L
A
I
M
E
N
Site 17
S176
N
V
L
A
R
Y
A
S
I
C
Q
Q
N
G
I
Site 18
Y204
H
D
L
K
R
C
Q
Y
V
T
E
K
V
L
A
Site 19
T206
L
K
R
C
Q
Y
V
T
E
K
V
L
A
A
V
Site 20
Y214
E
K
V
L
A
A
V
Y
K
A
L
S
D
H
H
Site 21
S218
A
A
V
Y
K
A
L
S
D
H
H
I
Y
L
E
Site 22
Y223
A
L
S
D
H
H
I
Y
L
E
G
T
L
L
K
Site 23
T235
L
L
K
P
N
M
V
T
P
G
H
A
C
T
Q
Site 24
T241
V
T
P
G
H
A
C
T
Q
K
F
S
H
E
E
Site 25
T269
P
P
A
V
T
G
I
T
F
L
S
G
G
Q
S
Site 26
S272
V
T
G
I
T
F
L
S
G
G
Q
S
E
E
E
Site 27
S276
T
F
L
S
G
G
Q
S
E
E
E
A
S
I
N
Site 28
S281
G
Q
S
E
E
E
A
S
I
N
L
N
A
I
N
Site 29
T299
L
L
K
P
W
A
L
T
F
S
Y
G
R
A
L
Site 30
S301
K
P
W
A
L
T
F
S
Y
G
R
A
L
Q
A
Site 31
Y302
P
W
A
L
T
F
S
Y
G
R
A
L
Q
A
S
Site 32
S309
Y
G
R
A
L
Q
A
S
A
L
K
A
W
G
G
Site 33
Y328
L
K
A
A
Q
E
E
Y
V
K
R
A
L
A
N
Site 34
S336
V
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Site 35
Y343
S
L
A
C
Q
G
K
Y
T
P
S
G
Q
A
G
Site 36
T344
L
A
C
Q
G
K
Y
T
P
S
G
Q
A
G
A
Site 37
S354
G
Q
A
G
A
A
A
S
E
S
L
F
V
S
N
Site 38
S356
A
G
A
A
A
S
E
S
L
F
V
S
N
H
A
Site 39
Y364
L
F
V
S
N
H
A
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation