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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VTN
Full Name:
Vitronectin
Alias:
S-protein;Serum-spreading factor;V75
Type:
Adhesion protein
Mass (Da):
54306
Number AA:
478
UniProt ID:
P04004
International Prot ID:
IPI00298971
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0008201
GO:0005515
GO:0005044
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
V
A
L
A
D
Q
E
S
C
K
G
R
C
T
E
Site 2
T29
E
S
C
K
G
R
C
T
E
G
F
N
V
D
K
Site 3
Y54
Y
Q
S
C
C
T
D
Y
T
A
E
C
K
P
Q
Site 4
T69
V
T
R
G
D
V
F
T
M
P
E
D
E
Y
T
Site 5
Y75
F
T
M
P
E
D
E
Y
T
V
Y
D
D
G
E
Site 6
T76
T
M
P
E
D
E
Y
T
V
Y
D
D
G
E
E
Site 7
Y78
P
E
D
E
Y
T
V
Y
D
D
G
E
E
K
N
Site 8
T88
G
E
E
K
N
N
A
T
V
H
E
Q
V
G
G
Site 9
S97
H
E
Q
V
G
G
P
S
L
T
S
D
L
Q
A
Site 10
T113
S
K
G
N
P
E
Q
T
P
V
L
K
P
E
E
Site 11
S130
P
A
P
E
V
G
A
S
K
P
E
G
I
D
S
Site 12
S137
S
K
P
E
G
I
D
S
R
P
E
T
L
H
P
Site 13
T141
G
I
D
S
R
P
E
T
L
H
P
G
R
P
Q
Site 14
S157
P
A
E
E
E
L
C
S
G
K
P
F
D
A
F
Site 15
T165
G
K
P
F
D
A
F
T
D
L
K
N
G
S
L
Site 16
S171
F
T
D
L
K
N
G
S
L
F
A
F
R
G
Q
Site 17
Y179
L
F
A
F
R
G
Q
Y
C
Y
E
L
D
E
K
Site 18
Y181
A
F
R
G
Q
Y
C
Y
E
L
D
E
K
A
V
Site 19
Y192
E
K
A
V
R
P
G
Y
P
K
L
I
R
D
V
Site 20
T219
R
I
N
C
Q
G
K
T
Y
L
F
K
G
S
Q
Site 21
Y220
I
N
C
Q
G
K
T
Y
L
F
K
G
S
Q
Y
Site 22
Y227
Y
L
F
K
G
S
Q
Y
W
R
F
E
D
G
V
Site 23
Y239
D
G
V
L
D
P
D
Y
P
R
N
I
S
D
G
Site 24
S244
P
D
Y
P
R
N
I
S
D
G
F
D
G
I
P
Site 25
S266
A
L
P
A
H
S
Y
S
G
R
E
R
V
Y
F
Site 26
Y272
Y
S
G
R
E
R
V
Y
F
F
K
G
K
Q
Y
Site 27
Y282
K
G
K
Q
Y
W
E
Y
Q
F
Q
H
Q
P
S
Site 28
S289
Y
Q
F
Q
H
Q
P
S
Q
E
E
C
E
G
S
Site 29
S297
Q
E
E
C
E
G
S
S
L
S
A
V
F
E
H
Site 30
S312
F
A
M
M
Q
R
D
S
W
E
D
I
F
E
L
Site 31
S326
L
L
F
W
G
R
T
S
A
G
T
R
Q
P
Q
Site 32
T329
W
G
R
T
S
A
G
T
R
Q
P
Q
F
I
S
Site 33
S364
S
G
M
A
P
R
P
S
L
A
K
K
Q
R
F
Site 34
Y379
R
H
R
N
R
K
G
Y
R
S
Q
R
G
H
S
Site 35
S381
R
N
R
K
G
Y
R
S
Q
R
G
H
S
R
G
Site 36
S386
Y
R
S
Q
R
G
H
S
R
G
R
N
Q
N
S
Site 37
S393
S
R
G
R
N
Q
N
S
R
R
P
S
R
A
T
Site 38
S397
N
Q
N
S
R
R
P
S
R
A
T
W
L
S
L
Site 39
T400
S
R
R
P
S
R
A
T
W
L
S
L
F
S
S
Site 40
S403
P
S
R
A
T
W
L
S
L
F
S
S
E
E
S
Site 41
S406
A
T
W
L
S
L
F
S
S
E
E
S
N
L
G
Site 42
S407
T
W
L
S
L
F
S
S
E
E
S
N
L
G
A
Site 43
S410
S
L
F
S
S
E
E
S
N
L
G
A
N
N
Y
Site 44
Y417
S
N
L
G
A
N
N
Y
D
D
Y
R
M
D
W
Site 45
Y420
G
A
N
N
Y
D
D
Y
R
M
D
W
L
V
P
Site 46
Y444
F
F
F
S
G
D
K
Y
Y
R
V
N
L
R
T
Site 47
Y445
F
F
S
G
D
K
Y
Y
R
V
N
L
R
T
R
Site 48
T451
Y
Y
R
V
N
L
R
T
R
R
V
D
T
V
D
Site 49
T456
L
R
T
R
R
V
D
T
V
D
P
P
Y
P
R
Site 50
Y461
V
D
T
V
D
P
P
Y
P
R
S
I
A
Q
Y
Site 51
S464
V
D
P
P
Y
P
R
S
I
A
Q
Y
W
L
G
Site 52
Y468
Y
P
R
S
I
A
Q
Y
W
L
G
C
P
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation