PhosphoNET

           
Protein Info 
   
Short Name:  FETUA
Full Name:  Alpha-2-HS-glycoprotein
Alias:  AHS; AHSG; Alpha-2-Z-globulin; Fetuin-A; HSGA
Type:  Endocytosis promoting protein. Possesses opsonic properties and influences the mineral phase of bone.
Mass (Da):  39325
Number AA:  367
UniProt ID:  P02765
International Prot ID:  IPI00022426
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615     Uniprot OncoNet
Molecular Function:  GO:0004869  GO:0019210  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006953  GO:0030502  GO:0046627 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18AQLWGCHSAPHGPGL
Site 2Y27PHGPGLIYRQPNCDD
Site 3T37PNCDDPETEEAALVA
Site 4S74KVWPQQPSGELFEIE
Site 5S101PTPVARCSVRQLKEH
Site 6Y129DGKFSVVYAKCDSSP
Site 7S134VVYAKCDSSPDSAED
Site 8S135VYAKCDSSPDSAEDV
Site 9S138KCDSSPDSAEDVRKV
Site 10T233QYGFCKATLSEKLGG
Site 11S235GFCKATLSEKLGGAE
Site 12T256VFQTQPVTSQPQPEG
Site 13T270GANEAVPTPVVDPDA
Site 14S280VDPDAPPSPPLGAPG
Site 15S293PGLPPAGSPPDSHVL
Site 16S297PAGSPPDSHVLLAAP
Site 17Y314HQLHRAHYDLRHTFM
Site 18S325HTFMGVVSLGSPSGE
Site 19S328MGVVSLGSPSGEVSH
Site 20S330VVSLGSPSGEVSHPR
Site 21S334GSPSGEVSHPRKTRT
Site 22T339EVSHPRKTRTVVQPS
Site 23T341SHPRKTRTVVQPSVG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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