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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC4A1
Full Name:
Band 3 anion transport protein
Alias:
AE 1; AE1; anion exchange protein 1; B3AT; Band 3; band 3 anion transport protein; CD233; CD233 antigen; CFB3; DI; EPB3; erythrocyte membrane protein band 3; FR; Froese blood group; RTA1A; solute carrier family 4, anion exchanger, member 1; SW; Swann blood group; WD; WR; Wright blood group
Type:
Transport protein, facilitator, activator
Mass (Da):
101792
Number AA:
911
UniProt ID:
P02730
International Prot ID:
IPI00022361
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016323
GO:0030863
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0030506
GO:0005452
GO:0043495
PhosphoSite+
KinaseNET
Biological Process:
GO:0006820
GO:0006873
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
E
E
L
Q
D
D
Y
E
D
M
M
E
E
N
Site 2
Y21
E
N
L
E
Q
E
E
Y
E
D
P
D
I
P
E
Site 3
S29
E
D
P
D
I
P
E
S
Q
M
E
E
P
A
A
Site 4
T39
E
E
P
A
A
H
D
T
E
A
T
A
T
D
Y
Site 5
T42
A
A
H
D
T
E
A
T
A
T
D
Y
H
T
T
Site 6
T44
H
D
T
E
A
T
A
T
D
Y
H
T
T
S
H
Site 7
Y46
T
E
A
T
A
T
D
Y
H
T
T
S
H
P
G
Site 8
T48
A
T
A
T
D
Y
H
T
T
S
H
P
G
T
H
Site 9
T49
T
A
T
D
Y
H
T
T
S
H
P
G
T
H
K
Site 10
S50
A
T
D
Y
H
T
T
S
H
P
G
T
H
K
V
Site 11
T54
H
T
T
S
H
P
G
T
H
K
V
Y
V
E
L
Site 12
Y58
H
P
G
T
H
K
V
Y
V
E
L
Q
E
L
V
Site 13
S162
R
A
L
L
L
K
H
S
H
A
G
E
L
E
A
Site 14
T179
G
V
K
P
A
V
L
T
R
S
G
D
P
S
Q
Site 15
S181
K
P
A
V
L
T
R
S
G
D
P
S
Q
P
L
Site 16
S185
L
T
R
S
G
D
P
S
Q
P
L
L
P
Q
H
Site 17
S193
Q
P
L
L
P
Q
H
S
S
L
E
T
Q
L
F
Site 18
S194
P
L
L
P
Q
H
S
S
L
E
T
Q
L
F
C
Site 19
T197
P
Q
H
S
S
L
E
T
Q
L
F
C
E
Q
G
Site 20
T208
C
E
Q
G
D
G
G
T
E
G
H
S
P
S
G
Site 21
S212
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
Site 22
S214
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
Site 23
Y278
P
E
A
P
H
I
D
Y
T
Q
L
G
R
A
A
Site 24
T279
E
A
P
H
I
D
Y
T
Q
L
G
R
A
A
A
Site 25
S290
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
Site 26
Y299
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
Site 27
S303
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
Site 28
S310
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
Site 29
T324
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
Site 30
S328
L
P
P
T
D
A
P
S
E
Q
A
L
L
S
L
Site 31
S334
P
S
E
Q
A
L
L
S
L
V
P
V
Q
R
E
Site 32
Y347
R
E
L
L
R
R
R
Y
Q
S
S
P
A
K
P
Site 33
S349
L
L
R
R
R
Y
Q
S
S
P
A
K
P
D
S
Site 34
S350
L
R
R
R
Y
Q
S
S
P
A
K
P
D
S
S
Site 35
S356
S
S
P
A
K
P
D
S
S
F
Y
K
G
L
D
Site 36
S357
S
P
A
K
P
D
S
S
F
Y
K
G
L
D
L
Site 37
Y359
A
K
P
D
S
S
F
Y
K
G
L
D
L
N
G
Site 38
Y390
V
R
D
I
R
R
R
Y
P
Y
Y
L
S
D
I
Site 39
Y392
D
I
R
R
R
Y
P
Y
Y
L
S
D
I
T
D
Site 40
Y393
I
R
R
R
Y
P
Y
Y
L
S
D
I
T
D
A
Site 41
S395
R
R
Y
P
Y
Y
L
S
D
I
T
D
A
F
S
Site 42
T398
P
Y
Y
L
S
D
I
T
D
A
F
S
P
Q
V
Site 43
T431
G
G
L
L
G
E
K
T
R
N
Q
M
G
V
S
Site 44
S438
T
R
N
Q
M
G
V
S
E
L
L
I
S
T
A
Site 45
S525
R
Y
T
Q
E
I
F
S
F
L
I
S
L
I
F
Site 46
T552
Q
D
H
P
L
Q
K
T
Y
N
Y
N
V
L
M
Site 47
Y553
D
H
P
L
Q
K
T
Y
N
Y
N
V
L
M
V
Site 48
S594
M
L
R
K
F
K
N
S
S
Y
F
P
G
K
L
Site 49
S595
L
R
K
F
K
N
S
S
Y
F
P
G
K
L
R
Site 50
Y596
R
K
F
K
N
S
S
Y
F
P
G
K
L
R
R
Site 51
T627
V
D
F
F
I
Q
D
T
Y
T
Q
K
L
S
V
Site 52
Y628
D
F
F
I
Q
D
T
Y
T
Q
K
L
S
V
P
Site 53
T629
F
F
I
Q
D
T
Y
T
Q
K
L
S
V
P
D
Site 54
S633
D
T
Y
T
Q
K
L
S
V
P
D
G
F
K
V
Site 55
S641
V
P
D
G
F
K
V
S
N
S
S
A
R
G
W
Site 56
S643
D
G
F
K
V
S
N
S
S
A
R
G
W
V
I
Site 57
S644
G
F
K
V
S
N
S
S
A
R
G
W
V
I
H
Site 58
T727
G
M
P
W
L
S
A
T
T
V
R
S
V
T
H
Site 59
Y818
L
L
F
K
P
P
K
Y
H
P
D
V
P
Y
V
Site 60
Y824
K
Y
H
P
D
V
P
Y
V
K
R
V
K
T
W
Site 61
T894
D
A
D
D
A
K
A
T
F
D
E
E
E
G
R
Site 62
Y904
E
E
E
G
R
D
E
Y
D
E
V
A
M
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation