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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Fos
Full Name:
Proto-oncogene c-Fos
Alias:
Cellular oncogene fos
Type:
Transcription protein
Mass (Da):
40695
Number AA:
380
UniProt ID:
P01100
International Prot ID:
IPI00033008
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0070412
GO:0010843
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0006306
GO:0060395
GO:0034614
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
F
S
G
F
N
A
D
Y
E
A
S
S
S
R
C
Site 2
S13
F
N
A
D
Y
E
A
S
S
S
R
C
S
S
A
Site 3
S14
N
A
D
Y
E
A
S
S
S
R
C
S
S
A
S
Site 4
S15
A
D
Y
E
A
S
S
S
R
C
S
S
A
S
P
Site 5
S18
E
A
S
S
S
R
C
S
S
A
S
P
A
G
D
Site 6
S19
A
S
S
S
R
C
S
S
A
S
P
A
G
D
S
Site 7
S21
S
S
R
C
S
S
A
S
P
A
G
D
S
L
S
Site 8
S26
S
A
S
P
A
G
D
S
L
S
Y
Y
H
S
P
Site 9
S28
S
P
A
G
D
S
L
S
Y
Y
H
S
P
A
D
Site 10
Y30
A
G
D
S
L
S
Y
Y
H
S
P
A
D
S
F
Site 11
S32
D
S
L
S
Y
Y
H
S
P
A
D
S
F
S
S
Site 12
S36
Y
Y
H
S
P
A
D
S
F
S
S
M
G
S
P
Site 13
S38
H
S
P
A
D
S
F
S
S
M
G
S
P
V
N
Site 14
S39
S
P
A
D
S
F
S
S
M
G
S
P
V
N
A
Site 15
S42
D
S
F
S
S
M
G
S
P
V
N
A
Q
D
F
Site 16
S84
V
Q
P
A
L
V
S
S
V
A
P
S
Q
T
R
Site 17
S88
L
V
S
S
V
A
P
S
Q
T
R
A
P
H
P
Site 18
T90
S
S
V
A
P
S
Q
T
R
A
P
H
P
F
G
Site 19
S102
P
F
G
V
P
A
P
S
A
G
A
Y
S
R
A
Site 20
Y106
P
A
P
S
A
G
A
Y
S
R
A
G
V
V
K
Site 21
T114
S
R
A
G
V
V
K
T
M
T
G
G
R
A
Q
Site 22
T116
A
G
V
V
K
T
M
T
G
G
R
A
Q
S
I
Site 23
S122
M
T
G
G
R
A
Q
S
I
G
R
R
G
K
V
Site 24
S133
R
G
K
V
E
Q
L
S
P
E
E
E
E
K
R
Site 25
T162
R
N
R
R
R
E
L
T
D
T
L
Q
A
E
T
Site 26
T164
R
R
R
E
L
T
D
T
L
Q
A
E
T
D
Q
Site 27
S177
D
Q
L
E
D
E
K
S
A
L
Q
T
E
I
A
Site 28
T181
D
E
K
S
A
L
Q
T
E
I
A
N
L
L
K
Site 29
T232
G
G
L
P
E
V
A
T
P
E
S
E
E
A
F
Site 30
S235
P
E
V
A
T
P
E
S
E
E
A
F
T
L
P
Site 31
T240
P
E
S
E
E
A
F
T
L
P
L
L
N
D
P
Site 32
S252
N
D
P
E
P
K
P
S
V
E
P
V
K
S
I
Site 33
S258
P
S
V
E
P
V
K
S
I
S
S
M
E
L
K
Site 34
S277
D
D
F
L
F
P
A
S
S
R
P
S
G
S
E
Site 35
S278
D
F
L
F
P
A
S
S
R
P
S
G
S
E
T
Site 36
S281
F
P
A
S
S
R
P
S
G
S
E
T
A
R
S
Site 37
S283
A
S
S
R
P
S
G
S
E
T
A
R
S
V
P
Site 38
T285
S
R
P
S
G
S
E
T
A
R
S
V
P
D
M
Site 39
S288
S
G
S
E
T
A
R
S
V
P
D
M
D
L
S
Site 40
S295
S
V
P
D
M
D
L
S
G
S
F
Y
A
A
D
Site 41
S297
P
D
M
D
L
S
G
S
F
Y
A
A
D
W
E
Site 42
Y299
M
D
L
S
G
S
F
Y
A
A
D
W
E
P
L
Site 43
S308
A
D
W
E
P
L
H
S
G
S
L
G
M
G
P
Site 44
S310
W
E
P
L
H
S
G
S
L
G
M
G
P
M
A
Site 45
T325
T
E
L
E
P
L
C
T
P
V
V
T
C
T
P
Site 46
T331
C
T
P
V
V
T
C
T
P
S
C
T
A
Y
T
Site 47
S340
S
C
T
A
Y
T
S
S
F
V
F
T
Y
P
E
Site 48
T344
Y
T
S
S
F
V
F
T
Y
P
E
A
D
S
F
Site 49
Y345
T
S
S
F
V
F
T
Y
P
E
A
D
S
F
P
Site 50
S350
F
T
Y
P
E
A
D
S
F
P
S
C
A
A
A
Site 51
S362
A
A
A
H
R
K
G
S
S
S
N
E
P
S
S
Site 52
S363
A
A
H
R
K
G
S
S
S
N
E
P
S
S
D
Site 53
S364
A
H
R
K
G
S
S
S
N
E
P
S
S
D
S
Site 54
S368
G
S
S
S
N
E
P
S
S
D
S
L
S
S
P
Site 55
S369
S
S
S
N
E
P
S
S
D
S
L
S
S
P
T
Site 56
S371
S
N
E
P
S
S
D
S
L
S
S
P
T
L
L
Site 57
S373
E
P
S
S
D
S
L
S
S
P
T
L
L
A
L
Site 58
S374
P
S
S
D
S
L
S
S
P
T
L
L
A
L
_
Site 59
T376
S
D
S
L
S
S
P
T
L
L
A
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation