PhosphoNET

           
Protein Info 
   
Short Name:  CA2
Full Name:  Carbonic anhydrase 2
Alias:  CA II; CAH2; CAII; CA-II; Car2; Carbonate dehydratase II; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic anhydrase II, CA II; Carbonic dehydratase; EC 4.2.1.1
Type:  Lyase; EC 4.2.1.1; Energy Metabolism - nitrogen
Mass (Da):  29115
Number AA:  259
UniProt ID:  P00918
International Prot ID:  IPI00218414
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0045177  GO:0005737  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0004089  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0006730     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S29IAKGERQSPVDIDTH
Site 2T35QSPVDIDTHTAKYDP
Site 3T37PVDIDTHTAKYDPSL
Site 4Y40IDTHTAKYDPSLKPL
Site 5S43HTAKYDPSLKPLSVS
Site 6S48DPSLKPLSVSYDQAT
Site 7S50SLKPLSVSYDQATSL
Site 8Y51LKPLSVSYDQATSLR
Site 9T55SVSYDQATSLRILNN
Site 10S56VSYDQATSLRILNNG
Site 11S73FNVEFDDSQDKAVLK
Site 12T87KGGPLDGTYRLIQFH
Site 13Y88GGPLDGTYRLIQFHF
Site 14S99QFHFHWGSLDGQGSE
Site 15T108DGQGSEHTVDKKKYA
Site 16Y114HTVDKKKYAAELHLV
Site 17Y127LVHWNTKYGDFGKAV
Site 18S165KVVDVLDSIKTKGKS
Site 19T168DVLDSIKTKGKSADF
Site 20S172SIKTKGKSADFTNFD
Site 21T176KGKSADFTNFDPRGL
Site 22S187PRGLLPESLDYWTYP
Site 23Y190LLPESLDYWTYPGSL
Site 24T192PESLDYWTYPGSLTT
Site 25Y193ESLDYWTYPGSLTTP
Site 26S196DYWTYPGSLTTPPLL
Site 27T198WTYPGSLTTPPLLEC
Site 28S218LKEPISVSSEQVLKF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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