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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLUD1
Full Name:
Glutamate dehydrogenase 1, mitochondrial
Alias:
DHE3; GDH; GLUD; Glutamate dehydrogenase 1; Glutamate dehydrogenase 1, mitochondrial
Type:
Amino Acid Metabolism - alanine, aspartate and glutamate; Other Amino Acids Metabolism - D-Glutamine and D-glutamate; Amino Acid Metabolism - arginine and proline; EC 1.4.1.3; Energy Metabolism - nitrogen; Oxidoreductase
Mass (Da):
61398
Number AA:
558
UniProt ID:
P00367
International Prot ID:
IPI00016801
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0043531
GO:0005524
GO:0005525
PhosphoSite+
KinaseNET
Biological Process:
GO:0006537
GO:0019459
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
A
G
P
A
A
L
G
S
A
S
A
D
S
A
A
Site 2
Y53
A
L
A
A
R
R
H
Y
S
E
A
V
A
D
R
Site 3
S54
L
A
A
R
R
H
Y
S
E
A
V
A
D
R
E
Site 4
S79
G
F
F
D
R
G
A
S
I
V
E
D
K
L
V
Site 5
T91
K
L
V
E
D
L
R
T
R
E
S
E
E
Q
K
Site 6
S94
E
D
L
R
T
R
E
S
E
E
Q
K
R
N
R
Site 7
S117
K
P
C
N
H
V
L
S
L
S
F
P
I
R
R
Site 8
S119
C
N
H
V
L
S
L
S
F
P
I
R
R
D
D
Site 9
S128
P
I
R
R
D
D
G
S
W
E
V
I
E
G
Y
Site 10
Y135
S
W
E
V
I
E
G
Y
R
A
Q
H
S
Q
H
Site 11
S140
E
G
Y
R
A
Q
H
S
Q
H
R
T
P
C
K
Site 12
T144
A
Q
H
S
Q
H
R
T
P
C
K
G
G
I
R
Site 13
Y152
P
C
K
G
G
I
R
Y
S
T
D
V
S
V
D
Site 14
S153
C
K
G
G
I
R
Y
S
T
D
V
S
V
D
E
Site 15
T154
K
G
G
I
R
Y
S
T
D
V
S
V
D
E
V
Site 16
S157
I
R
Y
S
T
D
V
S
V
D
E
V
K
A
L
Site 17
Y170
A
L
A
S
L
M
T
Y
K
C
A
V
V
D
V
Site 18
T206
E
K
I
T
R
R
F
T
M
E
L
A
K
K
G
Site 19
S227
D
V
P
A
P
D
M
S
T
G
E
R
E
M
S
Site 20
T228
V
P
A
P
D
M
S
T
G
E
R
E
M
S
W
Site 21
S234
S
T
G
E
R
E
M
S
W
I
A
D
T
Y
A
Site 22
Y240
M
S
W
I
A
D
T
Y
A
S
T
I
G
H
Y
Site 23
S261
C
V
T
G
K
P
I
S
Q
G
G
I
H
G
R
Site 24
T272
I
H
G
R
I
S
A
T
G
R
G
V
F
H
G
Site 25
T296
Y
M
S
I
L
G
M
T
P
G
F
G
D
K
T
Site 26
Y319
V
G
L
H
S
M
R
Y
L
H
R
F
G
A
K
Site 27
S336
A
V
G
E
S
D
G
S
I
W
N
P
D
G
I
Site 28
S357
D
F
K
L
Q
H
G
S
I
L
G
F
P
K
A
Site 29
S384
D
I
L
I
P
A
A
S
E
K
Q
L
T
K
S
Site 30
T389
A
A
S
E
K
Q
L
T
K
S
N
A
P
R
V
Site 31
S391
S
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Site 32
T409
A
E
G
A
N
G
P
T
T
P
E
A
D
K
I
Site 33
T410
E
G
A
N
G
P
T
T
P
E
A
D
K
I
F
Site 34
S438
N
A
G
G
V
T
V
S
Y
F
E
W
L
K
N
Site 35
Y439
A
G
G
V
T
V
S
Y
F
E
W
L
K
N
L
Site 36
S450
L
K
N
L
N
H
V
S
Y
G
R
L
T
F
K
Site 37
Y451
K
N
L
N
H
V
S
Y
G
R
L
T
F
K
Y
Site 38
T455
H
V
S
Y
G
R
L
T
F
K
Y
E
R
D
S
Site 39
Y458
Y
G
R
L
T
F
K
Y
E
R
D
S
N
Y
H
Site 40
Y464
K
Y
E
R
D
S
N
Y
H
L
L
M
S
V
Q
Site 41
S469
S
N
Y
H
L
L
M
S
V
Q
E
S
L
E
R
Site 42
S473
L
L
M
S
V
Q
E
S
L
E
R
K
F
G
K
Site 43
S498
A
E
F
Q
D
R
I
S
G
A
S
E
K
D
I
Site 44
S501
Q
D
R
I
S
G
A
S
E
K
D
I
V
H
S
Site 45
Y512
I
V
H
S
G
L
A
Y
T
M
E
R
S
A
R
Site 46
T513
V
H
S
G
L
A
Y
T
M
E
R
S
A
R
Q
Site 47
S517
L
A
Y
T
M
E
R
S
A
R
Q
I
M
R
T
Site 48
T524
S
A
R
Q
I
M
R
T
A
M
K
Y
N
L
G
Site 49
Y528
I
M
R
T
A
M
K
Y
N
L
G
L
D
L
R
Site 50
Y539
L
D
L
R
T
A
A
Y
V
N
A
I
E
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation