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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAG3
Full Name:
BAG family molecular chaperone regulator 3
Alias:
BAG-3; BAG-family molecular chaperone regulator-3; BCL-2 binding athanogene- 3; BCL2-associated athanogene 3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS; Docking protein CAIR-1
Type:
Apoptosis protein
Mass (Da):
61595
Number AA:
575
UniProt ID:
O95817
International Prot ID:
IPI00641582
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0030192
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
A
A
T
H
S
P
M
M
Q
V
A
S
Site 2
T34
E
I
K
I
D
P
Q
T
G
W
P
F
F
V
D
Site 3
T47
V
D
H
N
S
R
T
T
T
W
N
D
P
R
V
Site 4
T48
D
H
N
S
R
T
T
T
W
N
D
P
R
V
P
Site 5
S56
W
N
D
P
R
V
P
S
E
G
P
K
E
T
P
Site 6
T62
P
S
E
G
P
K
E
T
P
S
S
A
N
G
P
Site 7
S64
E
G
P
K
E
T
P
S
S
A
N
G
P
S
R
Site 8
S65
G
P
K
E
T
P
S
S
A
N
G
P
S
R
E
Site 9
S70
P
S
S
A
N
G
P
S
R
E
G
S
R
L
P
Site 10
S74
N
G
P
S
R
E
G
S
R
L
P
P
A
R
E
Site 11
Y86
A
R
E
G
H
P
V
Y
P
Q
L
R
P
G
Y
Site 12
Y93
Y
P
Q
L
R
P
G
Y
I
P
I
P
V
L
H
Site 13
T124
P
G
M
Q
R
F
R
T
E
A
A
A
A
A
P
Site 14
S134
A
A
A
A
P
Q
R
S
Q
S
P
L
R
G
M
Site 15
S136
A
A
P
Q
R
S
Q
S
P
L
R
G
M
P
E
Site 16
T144
P
L
R
G
M
P
E
T
T
Q
P
D
K
Q
C
Site 17
S165
A
A
A
Q
P
P
A
S
H
G
P
E
R
S
Q
Site 18
S171
A
S
H
G
P
E
R
S
Q
S
P
A
A
S
D
Site 19
S173
H
G
P
E
R
S
Q
S
P
A
A
S
D
C
S
Site 20
S177
R
S
Q
S
P
A
A
S
D
C
S
S
S
S
S
Site 21
S180
S
P
A
A
S
D
C
S
S
S
S
S
S
A
S
Site 22
S181
P
A
A
S
D
C
S
S
S
S
S
S
A
S
L
Site 23
S182
A
A
S
D
C
S
S
S
S
S
S
A
S
L
P
Site 24
S183
A
S
D
C
S
S
S
S
S
S
A
S
L
P
S
Site 25
S184
S
D
C
S
S
S
S
S
S
A
S
L
P
S
S
Site 26
S185
D
C
S
S
S
S
S
S
A
S
L
P
S
S
G
Site 27
S187
S
S
S
S
S
S
A
S
L
P
S
S
G
R
S
Site 28
S190
S
S
S
A
S
L
P
S
S
G
R
S
S
L
G
Site 29
S191
S
S
A
S
L
P
S
S
G
R
S
S
L
G
S
Site 30
S194
S
L
P
S
S
G
R
S
S
L
G
S
H
Q
L
Site 31
S195
L
P
S
S
G
R
S
S
L
G
S
H
Q
L
P
Site 32
S198
S
G
R
S
S
L
G
S
H
Q
L
P
R
G
Y
Site 33
Y205
S
H
Q
L
P
R
G
Y
I
S
I
P
V
I
H
Site 34
S207
Q
L
P
R
G
Y
I
S
I
P
V
I
H
E
Q
Site 35
T217
V
I
H
E
Q
N
V
T
R
P
A
A
Q
P
S
Site 36
S224
T
R
P
A
A
Q
P
S
F
H
Q
A
Q
K
T
Site 37
T231
S
F
H
Q
A
Q
K
T
H
Y
P
A
Q
Q
G
Site 38
Y233
H
Q
A
Q
K
T
H
Y
P
A
Q
Q
G
E
Y
Site 39
Y240
Y
P
A
Q
Q
G
E
Y
Q
T
H
Q
P
V
Y
Site 40
T242
A
Q
Q
G
E
Y
Q
T
H
Q
P
V
Y
H
K
Site 41
Y247
Y
Q
T
H
Q
P
V
Y
H
K
I
Q
G
D
D
Site 42
S264
P
R
P
L
R
A
A
S
P
F
R
S
S
V
Q
Site 43
S268
R
A
A
S
P
F
R
S
S
V
Q
G
A
S
S
Site 44
S269
A
A
S
P
F
R
S
S
V
Q
G
A
S
S
R
Site 45
S274
R
S
S
V
Q
G
A
S
S
R
E
G
S
P
A
Site 46
S275
S
S
V
Q
G
A
S
S
R
E
G
S
P
A
R
Site 47
S279
G
A
S
S
R
E
G
S
P
A
R
S
S
T
P
Site 48
S283
R
E
G
S
P
A
R
S
S
T
P
L
H
S
P
Site 49
S284
E
G
S
P
A
R
S
S
T
P
L
H
S
P
S
Site 50
T285
G
S
P
A
R
S
S
T
P
L
H
S
P
S
P
Site 51
S289
R
S
S
T
P
L
H
S
P
S
P
I
R
V
H
Site 52
S291
S
T
P
L
H
S
P
S
P
I
R
V
H
T
V
Site 53
T297
P
S
P
I
R
V
H
T
V
V
D
R
P
Q
Q
Site 54
T307
D
R
P
Q
Q
P
M
T
H
R
E
T
A
P
V
Site 55
T311
Q
P
M
T
H
R
E
T
A
P
V
S
Q
P
E
Site 56
S315
H
R
E
T
A
P
V
S
Q
P
E
N
K
P
E
Site 57
S323
Q
P
E
N
K
P
E
S
K
P
G
P
V
G
P
Site 58
S348
V
I
R
K
E
V
D
S
K
P
V
S
Q
K
P
Site 59
S352
E
V
D
S
K
P
V
S
Q
K
P
P
P
P
S
Site 60
S359
S
Q
K
P
P
P
P
S
E
K
V
E
V
K
V
Site 61
S377
P
V
P
C
P
P
P
S
P
G
P
S
A
V
P
Site 62
S381
P
P
P
S
P
G
P
S
A
V
P
S
S
P
K
Site 63
S385
P
G
P
S
A
V
P
S
S
P
K
S
V
A
T
Site 64
S386
G
P
S
A
V
P
S
S
P
K
S
V
A
T
E
Site 65
S389
A
V
P
S
S
P
K
S
V
A
T
E
E
R
A
Site 66
T392
S
S
P
K
S
V
A
T
E
E
R
A
A
P
S
Site 67
S399
T
E
E
R
A
A
P
S
T
A
P
A
E
A
T
Site 68
T400
E
E
R
A
A
P
S
T
A
P
A
E
A
T
P
Site 69
T406
S
T
A
P
A
E
A
T
P
P
K
P
G
E
A
Site 70
T447
D
N
F
E
G
K
K
T
D
K
K
Y
L
M
I
Site 71
Y451
G
K
K
T
D
K
K
Y
L
M
I
E
E
Y
L
Site 72
Y457
K
Y
L
M
I
E
E
Y
L
T
K
E
L
L
A
Site 73
S467
K
E
L
L
A
L
D
S
V
D
P
E
G
R
A
Site 74
Y508
V
P
G
Q
V
Q
V
Y
E
L
Q
P
S
N
L
Site 75
S513
Q
V
Y
E
L
Q
P
S
N
L
E
A
D
Q
P
Site 76
T547
G
N
A
E
D
P
H
T
E
T
Q
Q
P
E
A
Site 77
T549
A
E
D
P
H
T
E
T
Q
Q
P
E
A
T
A
Site 78
T559
P
E
A
T
A
A
A
T
S
N
P
S
S
M
T
Site 79
S560
E
A
T
A
A
A
T
S
N
P
S
S
M
T
D
Site 80
S564
A
A
T
S
N
P
S
S
M
T
D
T
P
G
N
Site 81
T568
N
P
S
S
M
T
D
T
P
G
N
P
A
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation