PhosphoNET

           
Protein Info 
   
Short Name:  FLOT1
Full Name:  Flotillin-1
Alias:  Flotillin 1;integral membrane component of caveolae
Type:  Uncharacterized protein
Mass (Da):  47355
Number AA:  427
UniProt ID:  O75955
International Prot ID:  IPI00027438
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0034451  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19VVSGFCRSPPVMVAG
Site 2S42IQQIQRISLNTLTLN
Site 3T47RISLNTLTLNVKSEK
Site 4S52TLTLNVKSEKVYTRH
Site 5Y56NVKSEKVYTRHGVPI
Site 6T57VKSEKVYTRHGVPIS
Site 7T116RAIMAHMTVEEIYKD
Site 8S128YKDRQKFSEQVFKVA
Site 9T150GISVVSYTLKDIHDD
Site 10Y160DIHDDQDYLHSLGKA
Site 11S163DDQDYLHSLGKARTA
Site 12Y203QEKVSAQYLSEIEMA
Site 13Y216MAKAQRDYELKKAAY
Site 14Y223YELKKAAYDIEVNTR
Site 15Y238RAQADLAYQLQVAKT
Site 16Y292KPAEAERYKLERLAE
Site 17S303RLAEAEKSQLIMQAE
Site 18S315QAEAEAASVRMRGEA
Site 19Y348KAEAFQLYQEAAQLD
Site 20T373EEISGPLTSANKITL
Site 21S383NKITLVSSGSGTMGA
Site 22S385ITLVSSGSGTMGAAK
Site 23T387LVSSGSGTMGAAKVT
Site 24S407ILTRLPESVERLTGV
Site 25T412PESVERLTGVSISQV
Site 26S415VERLTGVSISQVNHK
Site 27S417RLTGVSISQVNHKPL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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