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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Rad17
Full Name:
Cell cycle checkpoint protein RAD17
Alias:
hRad17; RF-C,activator 1 homolog
Type:
DNA repair protein
Mass (Da):
77055
Number AA:
681
UniProt ID:
O75943
International Prot ID:
IPI00395702
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0017111
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000077
GO:0006281
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
T
F
L
R
P
K
V
S
S
T
K
V
T
D
W
Site 2
S12
F
L
R
P
K
V
S
S
T
K
V
T
D
W
V
Site 3
T16
K
V
S
S
T
K
V
T
D
W
V
D
P
S
F
Site 4
S39
V
S
T
I
T
A
T
S
L
G
V
N
N
S
S
Site 5
S45
T
S
L
G
V
N
N
S
S
H
R
R
K
N
G
Site 6
S46
S
L
G
V
N
N
S
S
H
R
R
K
N
G
P
Site 7
S54
H
R
R
K
N
G
P
S
T
L
E
S
S
R
F
Site 8
T55
R
R
K
N
G
P
S
T
L
E
S
S
R
F
P
Site 9
S58
N
G
P
S
T
L
E
S
S
R
F
P
A
R
K
Site 10
S71
R
K
R
G
N
L
S
S
L
E
Q
I
Y
G
L
Site 11
S81
Q
I
Y
G
L
E
N
S
K
E
Y
L
S
E
N
Site 12
Y84
G
L
E
N
S
K
E
Y
L
S
E
N
E
P
W
Site 13
S86
E
N
S
K
E
Y
L
S
E
N
E
P
W
V
D
Site 14
Y95
N
E
P
W
V
D
K
Y
K
P
E
T
Q
H
E
Site 15
T99
V
D
K
Y
K
P
E
T
Q
H
E
L
A
V
H
Site 16
T115
K
K
I
E
E
V
E
T
W
L
K
A
Q
V
L
Site 17
S131
R
Q
P
K
Q
G
G
S
I
L
L
I
T
G
P
Site 18
T136
G
G
S
I
L
L
I
T
G
P
P
G
C
G
K
Site 19
T146
P
G
C
G
K
T
T
T
L
K
I
L
S
K
E
Site 20
S182
K
G
M
F
N
T
E
S
S
F
H
M
F
P
Y
Site 21
T204
K
E
F
L
L
R
A
T
K
Y
N
K
L
Q
M
Site 22
Y206
F
L
L
R
A
T
K
Y
N
K
L
Q
M
L
G
Site 23
Y233
E
D
L
P
N
Q
F
Y
R
D
S
H
T
L
H
Site 24
S236
P
N
Q
F
Y
R
D
S
H
T
L
H
E
V
L
Site 25
T238
Q
F
Y
R
D
S
H
T
L
H
E
V
L
R
K
Site 26
Y246
L
H
E
V
L
R
K
Y
V
R
I
G
R
C
P
Site 27
S263
F
I
I
S
D
S
L
S
G
D
N
N
Q
R
L
Site 28
S281
K
E
I
Q
E
E
C
S
I
S
N
I
S
F
N
Site 29
S283
I
Q
E
E
C
S
I
S
N
I
S
F
N
P
V
Site 30
T304
K
F
L
N
R
I
V
T
I
E
A
N
K
N
G
Site 31
T315
N
K
N
G
G
K
I
T
V
P
D
K
T
S
L
Site 32
S335
G
C
S
G
D
I
R
S
A
I
N
S
L
Q
F
Site 33
S339
D
I
R
S
A
I
N
S
L
Q
F
S
S
S
K
Site 34
S343
A
I
N
S
L
Q
F
S
S
S
K
G
E
N
N
Site 35
S345
N
S
L
Q
F
S
S
S
K
G
E
N
N
L
R
Site 36
S359
R
P
R
K
K
G
M
S
L
K
S
D
A
V
L
Site 37
S362
K
K
G
M
S
L
K
S
D
A
V
L
S
K
S
Site 38
S367
L
K
S
D
A
V
L
S
K
S
K
R
R
K
K
Site 39
S369
S
D
A
V
L
S
K
S
K
R
R
K
K
P
D
Site 40
S410
I
L
Y
C
K
R
A
S
L
T
E
L
D
S
P
Site 41
T412
Y
C
K
R
A
S
L
T
E
L
D
S
P
R
L
Site 42
S416
A
S
L
T
E
L
D
S
P
R
L
P
S
H
L
Site 43
S421
L
D
S
P
R
L
P
S
H
L
S
E
Y
E
R
Site 44
S424
P
R
L
P
S
H
L
S
E
Y
E
R
D
T
L
Site 45
Y426
L
P
S
H
L
S
E
Y
E
R
D
T
L
L
V
Site 46
T430
L
S
E
Y
E
R
D
T
L
L
V
E
P
E
E
Site 47
S442
P
E
E
V
V
E
M
S
H
M
P
G
D
L
F
Site 48
Y452
P
G
D
L
F
N
L
Y
L
H
Q
N
Y
I
D
Site 49
S481
L
S
F
A
D
I
L
S
G
D
W
N
T
R
S
Site 50
S488
S
G
D
W
N
T
R
S
L
L
R
E
Y
S
T
Site 51
Y493
T
R
S
L
L
R
E
Y
S
T
S
I
A
T
R
Site 52
S494
R
S
L
L
R
E
Y
S
T
S
I
A
T
R
G
Site 53
S505
A
T
R
G
V
M
H
S
N
K
A
R
G
Y
A
Site 54
Y511
H
S
N
K
A
R
G
Y
A
H
C
Q
G
G
G
Site 55
S519
A
H
C
Q
G
G
G
S
S
F
R
P
L
H
K
Site 56
S520
H
C
Q
G
G
G
S
S
F
R
P
L
H
K
P
Site 57
Y536
W
F
L
I
N
K
K
Y
R
E
N
C
L
A
A
Site 58
S579
M
R
N
Q
A
Q
I
S
F
I
Q
D
I
G
R
Site 59
T602
R
L
K
M
E
A
L
T
D
R
E
H
G
M
I
Site 60
S613
H
G
M
I
D
P
D
S
G
D
E
A
Q
L
N
Site 61
S624
A
Q
L
N
G
G
H
S
A
E
E
S
L
G
E
Site 62
S628
G
G
H
S
A
E
E
S
L
G
E
P
T
Q
A
Site 63
T636
L
G
E
P
T
Q
A
T
V
P
E
T
W
S
L
Site 64
T640
T
Q
A
T
V
P
E
T
W
S
L
P
L
S
Q
Site 65
S642
A
T
V
P
E
T
W
S
L
P
L
S
Q
N
S
Site 66
S646
E
T
W
S
L
P
L
S
Q
N
S
A
S
E
L
Site 67
S649
S
L
P
L
S
Q
N
S
A
S
E
L
P
A
S
Site 68
S651
P
L
S
Q
N
S
A
S
E
L
P
A
S
Q
P
Site 69
S656
S
A
S
E
L
P
A
S
Q
P
Q
P
F
S
A
Site 70
S662
A
S
Q
P
Q
P
F
S
A
Q
G
D
M
E
E
Site 71
Y676
E
N
I
I
I
E
D
Y
E
S
D
G
T
_
_
Site 72
S678
I
I
I
E
D
Y
E
S
D
G
T
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation