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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TOM1L1
Full Name:
TOM1-like protein 1
Alias:
Src activating and signaling molecule protein; Src-activating and signaling molecule protein; SRCASM; T1L1; Target of myb1-like 1; Target of myb-like 1 protein; Target of Myb-like protein 1; TM1L1; TOM1-like 1 protein
Type:
Adapter/scaffold protein
Mass (Da):
52989
Number AA:
476
UniProt ID:
O75674
International Prot ID:
IPI00023186
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005795
GO:0005829
GO:0010008
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0043130
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0043162
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
G
K
S
H
R
D
P
Y
A
T
S
V
G
H
L
Site 2
T13
S
H
R
D
P
Y
A
T
S
V
G
H
L
I
E
Site 3
T23
G
H
L
I
E
K
A
T
F
A
G
V
Q
T
E
Site 4
S61
K
A
L
K
K
R
I
S
K
N
Y
N
H
K
E
Site 5
Y64
K
K
R
I
S
K
N
Y
N
H
K
E
I
Q
L
Site 6
S89
N
C
G
P
S
F
Q
S
L
I
V
K
K
E
F
Site 7
Y109
V
K
L
L
N
P
R
Y
N
L
P
L
D
I
Q
Site 8
T125
R
I
L
N
F
I
K
T
W
S
Q
G
F
P
G
Site 9
S156
K
G
V
Q
F
P
P
S
E
A
E
A
E
T
A
Site 10
T167
A
E
T
A
R
Q
E
T
A
Q
I
S
S
N
P
Site 11
S171
R
Q
E
T
A
Q
I
S
S
N
P
P
T
S
V
Site 12
S172
Q
E
T
A
Q
I
S
S
N
P
P
T
S
V
P
Site 13
T176
Q
I
S
S
N
P
P
T
S
V
P
T
A
P
A
Site 14
S177
I
S
S
N
P
P
T
S
V
P
T
A
P
A
L
Site 15
S186
P
T
A
P
A
L
S
S
V
I
A
P
K
N
S
Site 16
S207
E
Q
I
G
K
L
H
S
E
L
D
M
V
K
M
Site 17
T227
S
A
I
L
M
E
N
T
P
G
S
E
N
H
E
Site 18
S230
L
M
E
N
T
P
G
S
E
N
H
E
D
I
E
Site 19
Y243
I
E
L
L
Q
K
L
Y
K
T
G
R
E
M
Q
Site 20
T245
L
L
Q
K
L
Y
K
T
G
R
E
M
Q
E
R
Site 21
Y283
L
N
N
A
I
L
G
Y
E
R
F
T
R
N
Q
Site 22
T287
I
L
G
Y
E
R
F
T
R
N
Q
Q
R
I
L
Site 23
T306
N
Q
K
E
A
T
N
T
T
S
E
P
S
A
P
Site 24
S308
K
E
A
T
N
T
T
S
E
P
S
A
P
S
Q
Site 25
S314
T
S
E
P
S
A
P
S
Q
D
L
L
D
L
S
Site 26
S321
S
Q
D
L
L
D
L
S
P
S
P
R
M
P
R
Site 27
S323
D
L
L
D
L
S
P
S
P
R
M
P
R
A
T
Site 28
T330
S
P
R
M
P
R
A
T
L
G
E
L
N
T
M
Site 29
T336
A
T
L
G
E
L
N
T
M
N
N
Q
L
S
G
Site 30
S342
N
T
M
N
N
Q
L
S
G
L
N
F
S
L
P
Site 31
S347
Q
L
S
G
L
N
F
S
L
P
S
S
D
V
T
Site 32
S351
L
N
F
S
L
P
S
S
D
V
T
N
N
L
K
Site 33
T354
S
L
P
S
S
D
V
T
N
N
L
K
P
S
L
Site 34
S360
V
T
N
N
L
K
P
S
L
H
P
Q
M
N
L
Site 35
S383
P
P
F
A
Q
R
T
S
Q
N
L
T
S
S
H
Site 36
T387
Q
R
T
S
Q
N
L
T
S
S
H
A
Y
D
N
Site 37
S389
T
S
Q
N
L
T
S
S
H
A
Y
D
N
F
L
Site 38
Y392
N
L
T
S
S
H
A
Y
D
N
F
L
E
H
S
Site 39
S399
Y
D
N
F
L
E
H
S
N
S
V
F
L
Q
P
Site 40
S401
N
F
L
E
H
S
N
S
V
F
L
Q
P
V
S
Site 41
S417
Q
T
I
A
A
A
P
S
N
Q
S
L
P
P
L
Site 42
S420
A
A
A
P
S
N
Q
S
L
P
P
L
P
S
N
Site 43
S426
Q
S
L
P
P
L
P
S
N
H
P
A
M
T
K
Site 44
S434
N
H
P
A
M
T
K
S
D
L
Q
P
P
N
Y
Site 45
Y441
S
D
L
Q
P
P
N
Y
Y
E
V
M
E
F
D
Site 46
Y442
D
L
Q
P
P
N
Y
Y
E
V
M
E
F
D
P
Site 47
T455
D
P
L
A
P
A
V
T
T
E
A
I
Y
E
E
Site 48
Y460
A
V
T
T
E
A
I
Y
E
E
I
D
A
H
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation