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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GMNN
Full Name:
Geminin
Alias:
Gem; GEMI; Geminin, DNA replication inhibitor
Type:
Cell cycle regulation
Mass (Da):
23565
Number AA:
209
UniProt ID:
O75496
International Prot ID:
IPI00026309
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0008156
GO:0045786
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
I
K
E
N
I
K
N
S
S
V
P
R
R
T
L
Site 2
S20
K
E
N
I
K
N
S
S
V
P
R
R
T
L
K
Site 3
T25
N
S
S
V
P
R
R
T
L
K
M
I
Q
P
S
Site 4
S34
K
M
I
Q
P
S
A
S
G
S
L
V
G
R
E
Site 5
S36
I
Q
P
S
A
S
G
S
L
V
G
R
E
N
E
Site 6
S45
V
G
R
E
N
E
L
S
A
G
L
S
K
R
K
Site 7
S49
N
E
L
S
A
G
L
S
K
R
K
H
R
N
D
Site 8
T59
K
H
R
N
D
H
L
T
S
T
T
S
S
P
G
Site 9
S60
H
R
N
D
H
L
T
S
T
T
S
S
P
G
V
Site 10
T61
R
N
D
H
L
T
S
T
T
S
S
P
G
V
I
Site 11
S63
D
H
L
T
S
T
T
S
S
P
G
V
I
V
P
Site 12
S64
H
L
T
S
T
T
S
S
P
G
V
I
V
P
E
Site 13
S72
P
G
V
I
V
P
E
S
S
E
N
K
N
L
G
Site 14
S73
G
V
I
V
P
E
S
S
E
N
K
N
L
G
G
Site 15
S85
L
G
G
V
T
Q
E
S
F
D
L
M
I
K
E
Site 16
S96
M
I
K
E
N
P
S
S
Q
Y
W
K
E
V
A
Site 17
Y111
E
K
R
R
K
A
L
Y
E
A
L
K
E
N
E
Site 18
Y150
E
V
A
E
H
V
Q
Y
M
A
E
L
I
E
R
Site 19
S168
E
P
L
D
N
F
E
S
L
D
N
Q
E
F
D
Site 20
S176
L
D
N
Q
E
F
D
S
E
E
E
T
V
E
D
Site 21
T180
E
F
D
S
E
E
E
T
V
E
D
S
L
V
E
Site 22
S184
E
E
E
T
V
E
D
S
L
V
E
D
S
E
I
Site 23
S189
E
D
S
L
V
E
D
S
E
I
G
T
C
A
E
Site 24
T193
V
E
D
S
E
I
G
T
C
A
E
G
T
V
S
Site 25
T198
I
G
T
C
A
E
G
T
V
S
S
S
T
D
A
Site 26
S200
T
C
A
E
G
T
V
S
S
S
T
D
A
K
P
Site 27
S201
C
A
E
G
T
V
S
S
S
T
D
A
K
P
C
Site 28
S202
A
E
G
T
V
S
S
S
T
D
A
K
P
C
I
Site 29
T203
E
G
T
V
S
S
S
T
D
A
K
P
C
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation