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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTNND1
Full Name:
Catenin delta-1
Alias:
cadherin-associated Src substrate; CAS; catenin, delta 1; catenin, delta-1; CATNS; CTD1; CTND1; CTNND; KIAA0384; p120; p120 catenin; p120(cas); p120(ctn); p120cas; p120ctn
Type:
Actin binding protein; Adaptor/scaffold; G protein regulator, misc.; Adhesion
Mass (Da):
108170
Number AA:
968
UniProt ID:
O60716
International Prot ID:
IPI00182540
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0045296
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0016337
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
D
D
S
E
V
E
S
T
A
S
Site 2
S8
M
D
D
S
E
V
E
S
T
A
S
I
L
A
S
Site 3
T9
D
D
S
E
V
E
S
T
A
S
I
L
A
S
V
Site 4
S11
S
E
V
E
S
T
A
S
I
L
A
S
V
K
E
Site 5
S15
S
T
A
S
I
L
A
S
V
K
E
Q
E
A
Q
Site 6
T27
E
A
Q
F
E
K
L
T
R
A
L
E
E
E
R
Site 7
S38
E
E
E
R
R
H
V
S
A
Q
L
E
R
V
R
Site 8
S47
Q
L
E
R
V
R
V
S
P
Q
D
A
N
P
L
Site 9
T59
N
P
L
M
A
N
G
T
L
T
R
R
H
Q
N
Site 10
T61
L
M
A
N
G
T
L
T
R
R
H
Q
N
G
R
Site 11
S92
L
N
G
P
Q
D
H
S
H
L
L
Y
S
T
I
Site 12
Y96
Q
D
H
S
H
L
L
Y
S
T
I
P
R
M
Q
Site 13
S97
D
H
S
H
L
L
Y
S
T
I
P
R
M
Q
E
Site 14
T98
H
S
H
L
L
Y
S
T
I
P
R
M
Q
E
P
Site 15
Y112
P
G
Q
I
V
E
T
Y
T
E
E
D
P
E
G
Site 16
S122
E
D
P
E
G
A
M
S
V
V
S
V
E
T
S
Site 17
S125
E
G
A
M
S
V
V
S
V
E
T
S
D
D
G
Site 18
S129
S
V
V
S
V
E
T
S
D
D
G
T
T
R
R
Site 19
T133
V
E
T
S
D
D
G
T
T
R
R
T
E
T
T
Site 20
T134
E
T
S
D
D
G
T
T
R
R
T
E
T
T
V
Site 21
T137
D
D
G
T
T
R
R
T
E
T
T
V
K
K
V
Site 22
T139
G
T
T
R
R
T
E
T
T
V
K
K
V
V
K
Site 23
T140
T
T
R
R
T
E
T
T
V
K
K
V
V
K
T
Site 24
T147
T
V
K
K
V
V
K
T
V
T
T
R
T
V
Q
Site 25
T149
K
K
V
V
K
T
V
T
T
R
T
V
Q
P
V
Site 26
T152
V
K
T
V
T
T
R
T
V
Q
P
V
A
M
G
Site 27
S168
D
G
L
P
V
D
A
S
S
V
S
N
N
Y
I
Site 28
S169
G
L
P
V
D
A
S
S
V
S
N
N
Y
I
Q
Site 29
S171
P
V
D
A
S
S
V
S
N
N
Y
I
Q
T
L
Site 30
Y174
A
S
S
V
S
N
N
Y
I
Q
T
L
G
R
D
Site 31
T177
V
S
N
N
Y
I
Q
T
L
G
R
D
F
R
K
Site 32
Y193
G
N
G
G
P
G
P
Y
V
G
Q
A
G
T
A
Site 33
T199
P
Y
V
G
Q
A
G
T
A
T
L
P
R
N
F
Site 34
T201
V
G
Q
A
G
T
A
T
L
P
R
N
F
H
Y
Site 35
Y208
T
L
P
R
N
F
H
Y
P
P
D
G
Y
S
R
Site 36
Y213
F
H
Y
P
P
D
G
Y
S
R
H
Y
E
D
G
Site 37
S214
H
Y
P
P
D
G
Y
S
R
H
Y
E
D
G
Y
Site 38
Y217
P
D
G
Y
S
R
H
Y
E
D
G
Y
P
G
G
Site 39
Y221
S
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Site 40
S225
E
D
G
Y
P
G
G
S
D
N
Y
G
S
L
S
Site 41
Y228
Y
P
G
G
S
D
N
Y
G
S
L
S
R
V
T
Site 42
S230
G
G
S
D
N
Y
G
S
L
S
R
V
T
R
I
Site 43
S232
S
D
N
Y
G
S
L
S
R
V
T
R
I
E
E
Site 44
T235
Y
G
S
L
S
R
V
T
R
I
E
E
R
Y
R
Site 45
Y241
V
T
R
I
E
E
R
Y
R
P
S
M
E
G
Y
Site 46
S244
I
E
E
R
Y
R
P
S
M
E
G
Y
R
A
P
Site 47
Y248
Y
R
P
S
M
E
G
Y
R
A
P
S
R
Q
D
Site 48
S252
M
E
G
Y
R
A
P
S
R
Q
D
V
Y
G
P
Site 49
Y257
A
P
S
R
Q
D
V
Y
G
P
Q
P
Q
V
R
Site 50
S268
P
Q
V
R
V
G
G
S
S
V
D
L
H
R
F
Site 51
S269
Q
V
R
V
G
G
S
S
V
D
L
H
R
F
H
Site 52
Y280
H
R
F
H
P
E
P
Y
G
L
E
D
D
Q
R
Site 53
S288
G
L
E
D
D
Q
R
S
M
G
Y
D
D
L
D
Site 54
Y291
D
D
Q
R
S
M
G
Y
D
D
L
D
Y
G
M
Site 55
Y296
M
G
Y
D
D
L
D
Y
G
M
M
S
D
Y
G
Site 56
S300
D
L
D
Y
G
M
M
S
D
Y
G
T
A
R
R
Site 57
Y302
D
Y
G
M
M
S
D
Y
G
T
A
R
R
T
G
Site 58
T304
G
M
M
S
D
Y
G
T
A
R
R
T
G
T
P
Site 59
T308
D
Y
G
T
A
R
R
T
G
T
P
S
D
P
R
Site 60
T310
G
T
A
R
R
T
G
T
P
S
D
P
R
R
R
Site 61
S312
A
R
R
T
G
T
P
S
D
P
R
R
R
L
R
Site 62
S320
D
P
R
R
R
L
R
S
Y
E
D
M
I
G
E
Site 63
Y321
P
R
R
R
L
R
S
Y
E
D
M
I
G
E
E
Site 64
S331
M
I
G
E
E
V
P
S
D
Q
Y
Y
W
A
P
Site 65
Y334
E
E
V
P
S
D
Q
Y
Y
W
A
P
L
A
Q
Site 66
Y335
E
V
P
S
D
Q
Y
Y
W
A
P
L
A
Q
H
Site 67
S346
L
A
Q
H
E
R
G
S
L
A
S
L
D
S
L
Site 68
S349
H
E
R
G
S
L
A
S
L
D
S
L
R
K
G
Site 69
S352
G
S
L
A
S
L
D
S
L
R
K
G
G
P
P
Site 70
S384
F
R
L
D
A
V
K
S
N
A
A
A
Y
L
Q
Site 71
Y395
A
Y
L
Q
H
L
C
Y
R
N
D
K
V
K
T
Site 72
T402
Y
R
N
D
K
V
K
T
D
V
R
K
L
K
G
Site 73
S436
C
G
A
L
K
N
I
S
F
G
R
D
Q
D
N
Site 74
T469
K
A
R
D
M
D
L
T
E
V
I
T
G
T
L
Site 75
S480
T
G
T
L
W
N
L
S
S
H
D
S
I
K
M
Site 76
S481
G
T
L
W
N
L
S
S
H
D
S
I
K
M
E
Site 77
S484
W
N
L
S
S
H
D
S
I
K
M
E
I
V
D
Site 78
S506
D
E
V
I
I
P
H
S
G
W
E
R
E
P
N
Site 79
S538
A
G
C
L
R
N
V
S
S
E
R
S
E
A
R
Site 80
S539
G
C
L
R
N
V
S
S
E
R
S
E
A
R
R
Site 81
S542
R
N
V
S
S
E
R
S
E
A
R
R
K
L
R
Site 82
S571
A
E
I
G
Q
K
D
S
D
S
K
L
V
E
N
Site 83
S573
I
G
Q
K
D
S
D
S
K
L
V
E
N
C
V
Site 84
S587
V
C
L
L
R
N
L
S
Y
Q
V
H
R
E
I
Site 85
Y588
C
L
L
R
N
L
S
Y
Q
V
H
R
E
I
P
Site 86
Y600
E
I
P
Q
A
E
R
Y
Q
E
A
A
P
N
V
Site 87
S630
K
G
K
D
E
W
F
S
R
G
K
K
P
I
E
Site 88
T643
I
E
D
P
A
N
D
T
V
D
F
P
K
R
T
Site 89
S651
V
D
F
P
K
R
T
S
P
A
R
G
Y
E
L
Site 90
Y656
R
T
S
P
A
R
G
Y
E
L
L
F
Q
P
E
Site 91
Y668
Q
P
E
V
V
R
I
Y
I
S
L
L
K
E
S
Site 92
S670
E
V
V
R
I
Y
I
S
L
L
K
E
S
K
T
Site 93
S675
Y
I
S
L
L
K
E
S
K
T
P
A
I
L
E
Site 94
T677
S
L
L
K
E
S
K
T
P
A
I
L
E
A
S
Site 95
Y698
L
C
A
G
R
W
T
Y
G
R
Y
I
R
S
A
Site 96
Y701
G
R
W
T
Y
G
R
Y
I
R
S
A
L
R
Q
Site 97
T720
S
A
I
A
D
L
L
T
N
E
H
E
R
V
V
Site 98
S731
E
R
V
V
K
A
A
S
G
A
L
R
N
L
A
Site 99
S766
L
P
G
G
Q
Q
N
S
S
W
N
F
S
E
D
Site 100
S767
P
G
G
Q
Q
N
S
S
W
N
F
S
E
D
T
Site 101
S771
Q
N
S
S
W
N
F
S
E
D
T
V
I
S
I
Site 102
T774
S
W
N
F
S
E
D
T
V
I
S
I
L
N
T
Site 103
S777
F
S
E
D
T
V
I
S
I
L
N
T
I
N
E
Site 104
T781
T
V
I
S
I
L
N
T
I
N
E
V
I
A
E
Site 105
T799
A
A
K
K
L
R
E
T
Q
G
I
E
K
L
V
Site 106
S811
K
L
V
L
I
N
K
S
G
N
R
S
E
K
E
Site 107
S815
I
N
K
S
G
N
R
S
E
K
E
V
R
A
A
Site 108
S847
E
K
E
G
W
K
K
S
D
F
Q
V
N
L
N
Site 109
S857
Q
V
N
L
N
N
A
S
R
S
Q
S
S
H
S
Site 110
S859
N
L
N
N
A
S
R
S
Q
S
S
H
S
Y
D
Site 111
S861
N
N
A
S
R
S
Q
S
S
H
S
Y
D
D
S
Site 112
S862
N
A
S
R
S
Q
S
S
H
S
Y
D
D
S
T
Site 113
S864
S
R
S
Q
S
S
H
S
Y
D
D
S
T
L
P
Site 114
Y865
R
S
Q
S
S
H
S
Y
D
D
S
T
L
P
L
Site 115
S868
S
S
H
S
Y
D
D
S
T
L
P
L
I
D
R
Site 116
T869
S
H
S
Y
D
D
S
T
L
P
L
I
D
R
N
Site 117
S879
L
I
D
R
N
Q
K
S
D
K
K
P
D
R
E
Site 118
S891
D
R
E
E
I
Q
M
S
N
M
G
S
N
T
K
Site 119
S895
I
Q
M
S
N
M
G
S
N
T
K
S
L
D
N
Site 120
T897
M
S
N
M
G
S
N
T
K
S
L
D
N
N
Y
Site 121
S899
N
M
G
S
N
T
K
S
L
D
N
N
Y
S
T
Site 122
Y904
T
K
S
L
D
N
N
Y
S
T
P
N
E
R
G
Site 123
S905
K
S
L
D
N
N
Y
S
T
P
N
E
R
G
D
Site 124
T906
S
L
D
N
N
Y
S
T
P
N
E
R
G
D
H
Site 125
T916
E
R
G
D
H
N
R
T
L
D
R
S
G
D
L
Site 126
S920
H
N
R
T
L
D
R
S
G
D
L
G
D
M
E
Site 127
T933
M
E
P
L
K
G
T
T
P
L
M
Q
D
E
G
Site 128
S943
M
Q
D
E
G
Q
E
S
L
E
E
E
L
D
V
Site 129
S961
D
D
E
G
G
Q
V
S
Y
P
S
M
Q
K
I
Site 130
Y962
D
E
G
G
Q
V
S
Y
P
S
M
Q
K
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation