PhosphoNET

           
Protein Info 
   
Short Name:  PRPF3
Full Name:  U4/U6 small nuclear ribonucleoprotein Prp3
Alias:  HPRP3; HPRP3P; Pre-mRNA-splicing factor 3; PRP3; PRP3 Prp3p; RP18
Type:  RNA processing
Mass (Da):  77529
Number AA:  683
UniProt ID:  O43395
International Prot ID:  IPI00005861
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0005681  GO:0016604 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0005488  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0000375  GO:0000377  GO:0000398 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T18LKPWIEKTVKRVLGF
Site 2S58LKPFLDDSTLRFVDK
Site 3T59KPFLDDSTLRFVDKL
Site 4S75EAVEEGRSSRHSKSS
Site 5S76AVEEGRSSRHSKSSS
Site 6S79EGRSSRHSKSSSDRS
Site 7S81RSSRHSKSSSDRSRK
Site 8S82SSRHSKSSSDRSRKR
Site 9S83SRHSKSSSDRSRKRE
Site 10S86SKSSSDRSRKRELKE
Site 11S99KEVFGDDSEISKESS
Site 12S102FGDDSEISKESSGVK
Site 13S105DSEISKESSGVKKRR
Site 14S106SEISKESSGVKKRRI
Site 15S131EVIPGPPSESPGMLT
Site 16S133IPGPPSESPGMLTKL
Site 17S161EERKKQLSFISPPTP
Site 18S164KKQLSFISPPTPQPK
Site 19T167LSFISPPTPQPKTPS
Site 20T172PPTPQPKTPSSSQPE
Site 21S175PQPKTPSSSQPERLP
Site 22S176QPKTPSSSQPERLPI
Site 23T186ERLPIGNTIQPSQAA
Site 24T194IQPSQAATFMNDAIE
Site 25T254LKDQTKPTPLILDEQ
Site 26T264ILDEQGRTVDATGKE
Site 27T268QGRTVDATGKEIELT
Site 28T275TGKEIELTHRMPTLK
Site 29T280ELTHRMPTLKANIRA
Site 30S302QQLKEKPSEDMESNT
Site 31S307KPSEDMESNTFFDPR
Site 32T309SEDMESNTFFDPRVS
Site 33S316TFFDPRVSIAPSQRQ
Site 34S320PRVSIAPSQRQRRTF
Site 35T326PSQRQRRTFKFHDKG
Site 36T344KIAQRLRTKAQLEKL
Site 37S356EKLQAEISQAARKTG
Site 38T362ISQAARKTGIHTSTR
Site 39S367RKTGIHTSTRLALIA
Site 40T402IPNGFDLTEENPKRE
Site 41Y411ENPKREDYFGITNLV
Site 42T432NPPVDNDTPVTLGVY
Site 43T435VDNDTPVTLGVYLTK
Site 44Y439TPVTLGVYLTKKEQK
Site 45T452QKKLRRQTRREAQKE
Site 46S479PEPKVRISNLMRVLG
Site 47T494TEAVQDPTKVEAHVR
Site 48T521ANAARKLTAEQRKVK
Site 49S538KKLKEDISQGVHISV
Site 50Y546QGVHISVYRVRNLSN
Site 51S552VYRVRNLSNPAKKFK
Site 52T608RIKWDEQTSNTKGDD
Site 53T611WDEQTSNTKGDDDEE
Site 54S619KGDDDEESDEEAVKK
Site 55S642EGTAKDRSFGEMKFK
Site 56S675HYWDLALSESVLEST
Site 57S677WDLALSESVLESTD_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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