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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPM1G
Full Name:
Protein phosphatase 1G
Alias:
EC 3.1.3.16; PP2C, gamma; PP2CG; PP2CGAMMA; PP2C-gamma; PPM1C; PPP2CG; Protein phosphatase 1C; Protein phosphatase 1G (formerly 2C) magnesium-dependent, gamma isoform; Protein phosphatase 2C gamma
Type:
EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)
Mass (Da):
59272
Number AA:
546
UniProt ID:
O15355
International Prot ID:
IPI00006167
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0008287
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0030145
GO:0004722
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
A
Y
L
S
Q
P
N
T
V
K
C
S
G
D
G
Site 2
S14
Q
P
N
T
V
K
C
S
G
D
G
V
G
A
P
Site 3
Y27
A
P
R
L
P
L
P
Y
G
F
S
A
M
Q
G
Site 4
T53
I
P
E
L
D
S
E
T
A
M
F
S
V
Y
D
Site 5
S57
D
S
E
T
A
M
F
S
V
Y
D
G
H
G
G
Site 6
Y59
E
T
A
M
F
S
V
Y
D
G
H
G
G
E
E
Site 7
Y70
G
G
E
E
V
A
L
Y
C
A
K
Y
L
P
D
Site 8
T122
A
Q
I
A
G
R
P
T
E
D
E
D
E
K
E
Site 9
T152
L
H
E
E
A
T
M
T
I
E
E
L
L
T
R
Site 10
S171
C
H
K
G
P
P
H
S
K
S
G
G
G
T
G
Site 11
S173
K
G
P
P
H
S
K
S
G
G
G
T
G
E
E
Site 12
T177
H
S
K
S
G
G
G
T
G
E
E
P
G
S
Q
Site 13
S183
G
T
G
E
E
P
G
S
Q
G
L
N
G
E
A
Site 14
S195
G
E
A
G
P
E
D
S
T
R
E
T
P
S
Q
Site 15
T196
E
A
G
P
E
D
S
T
R
E
T
P
S
Q
E
Site 16
T199
P
E
D
S
T
R
E
T
P
S
Q
E
N
G
P
Site 17
S201
D
S
T
R
E
T
P
S
Q
E
N
G
P
T
A
Site 18
T207
P
S
Q
E
N
G
P
T
A
K
A
Y
T
G
F
Site 19
Y211
N
G
P
T
A
K
A
Y
T
G
F
S
S
N
S
Site 20
T212
G
P
T
A
K
A
Y
T
G
F
S
S
N
S
E
Site 21
S216
K
A
Y
T
G
F
S
S
N
S
E
R
G
T
E
Site 22
S218
Y
T
G
F
S
S
N
S
E
R
G
T
E
A
G
Site 23
T222
S
S
N
S
E
R
G
T
E
A
G
Q
V
G
E
Site 24
T234
V
G
E
P
G
I
P
T
G
E
A
G
P
S
C
Site 25
S240
P
T
G
E
A
G
P
S
C
S
S
A
S
D
K
Site 26
S243
E
A
G
P
S
C
S
S
A
S
D
K
L
P
R
Site 27
S254
K
L
P
R
V
A
K
S
K
F
F
E
D
S
E
Site 28
S260
K
S
K
F
F
E
D
S
E
D
E
S
D
E
A
Site 29
S264
F
E
D
S
E
D
E
S
D
E
A
E
E
E
E
Site 30
S274
A
E
E
E
E
E
D
S
E
E
C
S
E
E
E
Site 31
S278
E
E
D
S
E
E
C
S
E
E
E
D
G
Y
S
Site 32
Y284
C
S
E
E
E
D
G
Y
S
S
E
E
A
E
N
Site 33
S285
S
E
E
E
D
G
Y
S
S
E
E
A
E
N
E
Site 34
T298
N
E
E
D
E
D
D
T
E
E
A
E
E
D
D
Site 35
S325
E
G
K
E
E
P
G
S
D
S
G
T
T
A
V
Site 36
S327
K
E
E
P
G
S
D
S
G
T
T
A
V
V
A
Site 37
S363
A
G
K
A
L
D
M
S
Y
D
H
K
P
E
D
Site 38
Y364
G
K
A
L
D
M
S
Y
D
H
K
P
E
D
E
Site 39
S397
V
N
G
G
L
N
L
S
R
A
I
G
D
H
F
Site 40
Y405
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Site 41
S419
P
P
E
E
Q
M
I
S
A
L
P
D
I
K
V
Site 42
T428
L
P
D
I
K
V
L
T
L
T
D
D
H
E
F
Site 43
S461
D
F
I
Q
S
K
I
S
Q
R
D
E
N
G
E
Site 44
T488
D
Q
C
L
A
P
D
T
S
G
D
G
T
G
C
Site 45
S489
Q
C
L
A
P
D
T
S
G
D
G
T
G
C
D
Site 46
T493
P
D
T
S
G
D
G
T
G
C
D
N
M
T
C
Site 47
T510
I
C
F
K
P
R
N
T
A
E
L
Q
P
E
S
Site 48
S517
T
A
E
L
Q
P
E
S
G
K
R
K
L
E
E
Site 49
S527
R
K
L
E
E
V
L
S
T
E
G
A
E
E
N
Site 50
T528
K
L
E
E
V
L
S
T
E
G
A
E
E
N
G
Site 51
S537
G
A
E
E
N
G
N
S
D
K
K
K
K
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation